Chemo- and Radiotherapy in Adjuvant Management of Optimally Debulked Endometrial Cancer

Authors: David Scott Miller MDa, Gini Fleming MDa, and Marcus E. Randall MDa
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  • a From the University of Texas Southwestern Medical Center, Dallas, Texas; University of Chicago Medical Center, Chicago, Illinois; and Department of Radiation Medicine, University of Kentucky School of Medicine, Lexington, Kentucky.
Volume/Issue:
Volume 7: Issue 5
Online Publication Date:
May 2009
DOI:
https://doi.org/10.6004/jnccn.2009.0036
Full access

The role of chemotherapy and radiotherapy in adjuvant management of optimally debulked endometrial cancer with extrauterine involvement is evolving. Recent studies have suggested an expanded role for chemotherapy and questioned the benefit of radiation therapy. Ongoing and planned clinical trials should provide clarification.

Dr. Miller is a principal investigator for Gynecologic Oncology Group (GOG) Protocol 209. Dr. Fleming is a principal investigator for a study partially funded by Wyeth, and is a principal investigator for 2 GOG trials; she is also on the GOG board of directors and Gynecologic Cancer Steering Committee. Dr. Randall has no financial interests, arrangement, or affiliations with the manufacturers of any products discussed in the article or their competitors.

Correspondence: Marcus E. Randall, MD, Department of Radiation Medicine, University of Kentucky School of Medicine, 800 Rose Street, Room N14, Lexington, KY 40536-0293. E-mail: merand2@email.uky.edu
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Copyright:
Copyright © 2009 by the National Comprehensive Cancer Network 2009
Page Numbers:
7
Article Category:
Research Article
Received:
03 Feb 2009
Accepted:
16 Mar 2009
Print Publication Date:
01 May 2009
Online Publication Date:
May 2009
Keywords:
Endometrial cancer; surgery; surgical staging; adjuvant radiotherapy; adjuvant chemotherapy; chemoradiotherapy
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