Combined Modality Therapy of Esophageal Cancer

Authors:
Rosalyn A. JuergensFrom The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

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Arlene ForastiereFrom The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

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Editor:
Kerrin G. RobinsonMedical/Scientific Editor, Journal of the National Comprehensive Cancer Network

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Esophageal cancer is a deadly disease. Only one third of patients with localized disease experience long-term survival. Over the past 20 years, investigators have evaluated neoadjuvant strategies to improve the outcomes of surgical management. Chemotherapy and radiation have been evaluated individually and in combination for preoperative management of patients with localized esophageal cancer. This article provides a critical review of the data on multimodality approaches to the management of esophageal cancer.

Correspondence: Rosalyn A. Juergens, MD, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Harry and Jeanette Weinberg Building, 401 North Broadway, Baltimore, MD 21231-2410. E-mail: rjuergens@jhmi.edu

Disclosure: Kerrin G. Robinson, MA, has disclosed no relevant financial relationships.

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