A Brief Review of Pharmacotherapies for Smoking Cessation

Authors:
Cho Y. LamFrom The University of Texas M. D. Anderson Cancer Center, Houston, Texas.

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Jennifer A. MinnixFrom The University of Texas M. D. Anderson Cancer Center, Houston, Texas.

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Jason D. RobinsonFrom The University of Texas M. D. Anderson Cancer Center, Houston, Texas.

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Paul M. CinciripiniFrom The University of Texas M. D. Anderson Cancer Center, Houston, Texas.

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Volume/Issue:
Volume 4: Issue 6
Online Publication Date:
Jul 2006
DOI:
https://doi.org/10.6004/jnccn.2006.0047
Full access

The U.S. Department of Health and Human Services' Clinical Practice Guidelines have established both nicotine and nonnicotine-based pharmacotherapies as efficacious treatments for smoking cessation. Smokers attempting to quit smoking can significantly increase their chances by using one of several first-line agents, including nicotine transdermal patches, gum, nasal spray, inhalers, tablets, and the antidepressant bupropion. Those who cannot use either bupropion or nicotine replacement therapy because of contraindications or lack of effectiveness may benefit from the second-line treatment nortriptyline. This article also discusses several novel compounds for smoking cessation.

Correspondence: Cho Y. Lam, PhD, Department of Behavioral Science – Unit 1330, The University of Texas M. D. Anderson Cancer Center, P. O. Box 301439, Houston, TX 77230-1439. E-mail: cholam@mdanderson.org
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Copyright:
Copyright © 2006 by the National Comprehensive Cancer Network
Page Numbers:
7
Article Category:
Research Article
Received:
14 Feb 2006
Accepted:
24 Mar 2006
Print Publication Date:
01 Jul 2006
Online Publication Date:
Jul 2006
Keywords:
Smoking cessation; pharmacotherapy; nicotine replacement treatment; antidepressant
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