Importance of Node Dissection in Relation to Neoadjuvant and Adjuvant Therapy

Jemal A, Murray T, Ward E et al.. Cancer statistics, 2005. CA Cancer J Clin 2005;55:10–30.

JemalAMurrayTWardE. Cancer statistics, 2005. CA Cancer J Clin 2005;55:10–30. )| false
• Search Google Scholar
• Export Citation

Colston J, Leadbetter W. Infiltrating carcinoma of the bladder. J Urol 1936;36:669–689.

ColstonJLeadbetterW. Infiltrating carcinoma of the bladder. J Urol 1936;36:669–689. )| false
• Search Google Scholar
• Export Citation

Leadbetter WF, Cooper JF. Regional gland dissection for carcinoma of the bladder; a technique for one-stage cystectomy, gland dissection, and bilateral uretero-enterostomy. J Urol 1950;63:242–260.

LeadbetterWFCooperJF. Regional gland dissection for carcinoma of the bladder; a technique for one-stage cystectomy, gland dissection, and bilateral uretero-enterostomy. J Urol 1950;63:242–260. )| false
• Search Google Scholar
• Export Citation

Mills RD, Turner WH, Fleischmann A et al.. Pelvic lymph node metastases from bladder cancer: outcome in 83 patients after radical cystectomy and pelvic lymphadenectomy. J Urol 2001;166:19–23.

MillsRDTurnerWHFleischmannA. Pelvic lymph node metastases from bladder cancer: outcome in 83 patients after radical cystectomy and pelvic lymphadenectomy. J Urol 2001;166:19–23. )| false
• Search Google Scholar
• Export Citation

Stein JP, Lieskovsky G, Cote R et al.. Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients. J Clin Oncol 2001;19:666–675.

SteinJPLieskovskyGCoteR. Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients. J Clin Oncol 2001;19:666–675. )| false
• Search Google Scholar
• Export Citation

Vieweg J, Gschwend JE, Herr HW et al.. Pelvic lymph node dissection can be curative in patients with node positive bladder cancer. J Urol 1999;161:449–454.

ViewegJGschwendJEHerrHW. Pelvic lymph node dissection can be curative in patients with node positive bladder cancer. J Urol 1999;161:449–454. )| false
• Search Google Scholar
• Export Citation

Leissner J, Ghoneim MA, Abol-Enein H et al.. Extended radical lymphadenectomy in patients with urothelial bladder cancer: results of a prospective multicenter study. J Urol 2004;171:139–144.

LeissnerJGhoneimMAAbol-EneinH. Extended radical lymphadenectomy in patients with urothelial bladder cancer: results of a prospective multicenter study. J Urol 2004;171:139–144. )| false
• Search Google Scholar
• Export Citation

Abol-Enein H, El-Baz M, Abd El-Hameed MA et al.. Lymph node involvement in patients with bladder cancer treated with radical cystectomy: a patho-anatomical study—a single center experience. J Urol 2004;172:1818–1821.

Abol-EneinHEl-BazMAbd El-HameedMA. Lymph node involvement in patients with bladder cancer treated with radical cystectomy: a patho-anatomical study—a single center experience. J Urol 2004;172:1818–1821. )| false
• Search Google Scholar
• Export Citation

Jewett HJ, Strong GH. Infiltrating carcinoma of the bladder: relation of depth and penetration of the bladder wall to incidence of local extension and metastasis. J Urol 1946;55:366–372.

JewettHJStrongGH. Infiltrating carcinoma of the bladder: relation of depth and penetration of the bladder wall to incidence of local extension and metastasis. J Urol 1946;55:366–372. )| false
• Search Google Scholar
• Export Citation

Ghoneim MA, el-Mekresh MM, el-Baz MA et al.. Radical cystectomy for carcinoma of the bladder: critical evaluation of the results in 1,026 cases. J Urol 1997;158:393–399.

GhoneimMAel-MekreshMMel-BazMA. Radical cystectomy for carcinoma of the bladder: critical evaluation of the results in 1,026 cases. J Urol 1997;158:393–399. )| false
• Search Google Scholar
• Export Citation

Leissner J, Hohenfellner R, Thuroff JW et al.. Lymphadenectomy in patients with transitional cell carcinoma of the urinary bladder; significance for staging and prognosis. BJU Int 2000;85:817–823.

LeissnerJHohenfellnerRThuroffJW. Lymphadenectomy in patients with transitional cell carcinoma of the urinary bladder; significance for staging and prognosis. BJU Int 2000;85:817–823. )| false
• Search Google Scholar
• Export Citation

International Bladder Cancer Nomogram Consortium. Postoperative nomogram predicting risk of recurrence following radical cystectomy for bladder cancer. J Clin Oncol 2006;24:3967–3972.

International Bladder Cancer Nomogram Consortium. Postoperative nomogram predicting risk of recurrence following radical cystectomy for bladder cancer. J Clin Oncol 2006;24:3967–3972. )| false
• Search Google Scholar
• Export Citation

Galsky MD, Bajorin DF. Chemotherapy for metastatic bladder, alone or in combination with other treatment. In: Vogelzang NJ, Scardino P, Shipley WU, et al., eds. Comprehensive Textbook of Genitourinary Oncology, 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2006:527–532.

GalskyMDBajorinDF. Chemotherapy for metastatic bladder, alone or in combination with other treatment. In: Vogelzang NJ, Scardino P, Shipley WU, et al., eds. Comprehensive Textbook of Genitourinary Oncology, 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2006:527–532. )| false
• Search Google Scholar
• Export Citation

Yagoda A. Phase II trials with cis-dichlorodiammineplatinum(II) in the treatment of urothelial cancer. Cancer Treat Rep 1979;63:1565–1572.

YagodaA. Phase II trials with cis-dichlorodiammineplatinum(II) in the treatment of urothelial cancer. Cancer Treat Rep 1979;63:1565–1572. )| false
• Search Google Scholar
• Export Citation

Sternberg CN, Yagoda A, Scher HI et al.. M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) for advanced transitional cell carcinoma of the urothelium. J Urol 1988;139:461–469.

SternbergCNYagodaAScherHI. M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) for advanced transitional cell carcinoma of the urothelium. J Urol 1988;139:461–469. )| false
• Search Google Scholar
• Export Citation

Loehrer PJ Sr, Einhorn LH, Elson PJ et al.. A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study. J Clin Oncol 1992;10:1066–1073.

LoehrerPJSrEinhornLHElsonPJ. A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study. J Clin Oncol 1992;10:1066–1073. )| false
• Search Google Scholar
• Export Citation

Logothetis CJ, Dexeus FH, Finn L et al.. A prospective randomized trial comparing MVAC and CISCA chemotherapy for patients with metastatic urothelial tumors. J Clin Oncol 1990;8:1050–1055.

LogothetisCJDexeusFHFinnL. A prospective randomized trial comparing MVAC and CISCA chemotherapy for patients with metastatic urothelial tumors. J Clin Oncol 1990;8:1050–1055. )| false
• Search Google Scholar
• Export Citation

von der Maase H, Hansen SW, Roberts JT et al.. Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III study. J Clin Oncol 2000;18:3068–3077.

von der MaaseHHansenSWRobertsJT. Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III study. J Clin Oncol 2000;18:3068–3077. )| false
• Search Google Scholar
• Export Citation

Grossman HB, Natale RB, Tangen CM et al.. Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer. N Engl J Med 2003;349:859–866.

GrossmanHBNataleRBTangenCM. Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer. N Engl J Med 2003;349:859–866. )| false
• Search Google Scholar
• Export Citation

Advanced Bladder Cancer Meta-Analysis Collaboration. Neoadjuvant chemotherapy in invasive bladder cancer: a systematic review and meta-analysis. Lancet 2003;361:1927–1934.

Advanced Bladder Cancer Meta-Analysis Collaboration. Neoadjuvant chemotherapy in invasive bladder cancer: a systematic review and meta-analysis. Lancet 2003;361:1927–1934. )| false
• Search Google Scholar
• Export Citation

Winquist E, Kirchner TS, Segal R et al.. Neoadjuvant chemotherapy for transitional cell carcinoma of the bladder: a systematic review and meta-analysis. J Urol 2004;171:561–569.

WinquistEKirchnerTSSegalR. Neoadjuvant chemotherapy for transitional cell carcinoma of the bladder: a systematic review and meta-analysis. J Urol 2004;171:561–569. )| false
• Search Google Scholar
• Export Citation

Skinner DG, Daniels JR, Russell CA et al.. The role of adjuvant chemotherapy following cystectomy for invasive bladder cancer: a prospective comparative trial. J Urol 1991;145:459–464; discussion 464–467.

SkinnerDGDanielsJRRussellCA. The role of adjuvant chemotherapy following cystectomy for invasive bladder cancer: a prospective comparative trial. J Urol 1991;145:459–464; discussion 464–467. )| false
• Search Google Scholar
• Export Citation

Stockle M, Meyenburg W, Wellek S et al.. Adjuvant polychemotherapy of nonorgan-confined bladder cancer after radical cystectomy revisited: long-term results of a controlled prospective study and further clinical experience. J Urol 1995;153:47–52.

StockleMMeyenburgWWellekS. Adjuvant polychemotherapy of nonorgan-confined bladder cancer after radical cystectomy revisited: long-term results of a controlled prospective study and further clinical experience. J Urol 1995;153:47–52. )| false
• Search Google Scholar
• Export Citation

Freiha F, Reese J, Torti FM. A randomized trial of radical cystectomy versus radical cystectomy plus cisplatin, vinblastine and methotrexate chemotherapy for muscle invasive bladder cancer. J Urol 1996;155:495–499; discussion 499–500.

FreihaFReeseJTortiFM. A randomized trial of radical cystectomy versus radical cystectomy plus cisplatin, vinblastine and methotrexate chemotherapy for muscle invasive bladder cancer. J Urol 1996;155:495–499; discussion 499–500. )| false
• Search Google Scholar
• Export Citation

Sylvester R, Sternberg C. The role of adjuvant combination chemotherapy after cystectomy in locally advanced bladder cancer: what we do not know and why. Ann Oncol 2000;11:851–856.

SylvesterRSternbergC. The role of adjuvant combination chemotherapy after cystectomy in locally advanced bladder cancer: what we do not know and why. Ann Oncol 2000;11:851–856. )| false
• Search Google Scholar
• Export Citation

Kerr W, Colby F. Pelvic lymph node dissection and total cystectomy in the treatment of carcinoma of the bladder. J Urol 1950;63:842–851.

KerrWColbyF. Pelvic lymph node dissection and total cystectomy in the treatment of carcinoma of the bladder. J Urol 1950;63:842–851. )| false
• Search Google Scholar
• Export Citation

Whitmore WF Jr, Marshall VF. Radical total cystectomy for cancer of the bladder: 230 consecutive cases five years later. J Urol 1962;87:853–868.

WhitmoreWFJrMarshallVF. Radical total cystectomy for cancer of the bladder: 230 consecutive cases five years later. J Urol 1962;87:853–868. )| false
• Search Google Scholar
• Export Citation

Dretler SP, Ragsdale BD, Leadbetter WF. The value of pelvic lymphadenectomy in the surgical treatment of bladder cancer. J Urol 1973;109:414–416.

DretlerSPRagsdaleBDLeadbetterWF. The value of pelvic lymphadenectomy in the surgical treatment of bladder cancer. J Urol 1973;109:414–416. )| false
• Search Google Scholar
• Export Citation

Skinner DG. Management of invasive bladder cancer: a meticulous pelvic node dissection can make a difference. J Urol 1982;128:34–36.

SkinnerDG. Management of invasive bladder cancer: a meticulous pelvic node dissection can make a difference. J Urol 1982;128:34–36. )| false
• Search Google Scholar
• Export Citation

Konety BR, Joslyn SA, O'Donnell MA. Extent of pelvic lymphadenectomy and its impact on outcome in patients diagnosed with bladder cancer: analysis of data from the Surveillance, Epidemiology and End Results Program data base. J Urol 2003;169:946–950.

KonetyBRJoslynSAO'DonnellMA. Extent of pelvic lymphadenectomy and its impact on outcome in patients diagnosed with bladder cancer: analysis of data from the Surveillance, Epidemiology and End Results Program data base. J Urol 2003;169:946–950. )| false
• Search Google Scholar
• Export Citation

Herr HW, Faulkner JR, Grossman HB et al.. Surgical factors influence bladder cancer outcomes: a cooperative group report. J Clin Oncol 2004;22:2781–2789.

HerrHWFaulknerJRGrossmanHB. Surgical factors influence bladder cancer outcomes: a cooperative group report. J Clin Oncol 2004;22:2781–2789. )| false
• Search Google Scholar
• Export Citation

Vazina A, Dugi D, Shariat SF et al.. Stage specific lymph node metastasis mapping in radical cystectomy specimens. J Urol 2004;171:1830–1834.

VazinaADugiDShariatSF. Stage specific lymph node metastasis mapping in radical cystectomy specimens. J Urol 2004;171:1830–1834. )| false
• Search Google Scholar
• Export Citation

Wishnow KI, Johnson DE, Ro JY et al.. Incidence, extent and location of unsuspected pelvic lymph node metastasis in patients undergoing radical cystectomy for bladder cancer. J Urol 1987;137:408–410.

WishnowKIJohnsonDERoJY. Incidence, extent and location of unsuspected pelvic lymph node metastasis in patients undergoing radical cystectomy for bladder cancer. J Urol 1987;137:408–410. )| false
• Search Google Scholar
• Export Citation

Ravery V, Chopin DK, Abbou CC. [Surgical anatomy of the lymphatic drainage of the bladder]. Ann Urol (Paris) 1993;27:9–11.

RaveryVChopinDKAbbouCC. [Surgical anatomy of the lymphatic drainage of the bladder]. Ann Urol (Paris) 1993;27:9–11. )| false
• Search Google Scholar
• Export Citation

Lerner SP, Skinner DG, Lieskovsky G et al.. The rationale for en bloc pelvic lymph node dissection for bladder cancer patients with nodal metastases: long-term results. J Urol 1993;149:758–764; discussion 764–765.

LernerSPSkinnerDGLieskovskyG. The rationale for en bloc pelvic lymph node dissection for bladder cancer patients with nodal metastases: long-term results. J Urol 1993;149:758–764; discussion 764–765. )| false
• Search Google Scholar
• Export Citation

Poulsen AL, Horn T, Steven K. Radical cystectomy: extending the limits of pelvic lymph node dissection improves survival for patients with bladder cancer confined to the bladder wall. J Urol 1998;160:2015–2019; discussion 2020.

PoulsenALHornTStevenK. Radical cystectomy: extending the limits of pelvic lymph node dissection improves survival for patients with bladder cancer confined to the bladder wall. J Urol 1998;160:2015–2019; discussion 2020. )| false
• Search Google Scholar
• Export Citation

Bochner BH, Cho D, Herr HW et al.. Prospectively packaged lymph node dissections with radical cystectomy: evaluation of node count variability and node mapping. J Urol 2004;172:1286–1290.

BochnerBHChoDHerrHW. Prospectively packaged lymph node dissections with radical cystectomy: evaluation of node count variability and node mapping. J Urol 2004;172:1286–1290. )| false
• Search Google Scholar
• Export Citation

Paik ML, Scolieri MJ, Brown SL et al.. Limitations of computerized tomography in staging invasive bladder cancer before radical cystectomy. J Urol 2000;163:1693–1696.

PaikMLScolieriMJBrownSL. Limitations of computerized tomography in staging invasive bladder cancer before radical cystectomy. J Urol 2000;163:1693–1696. )| false
• Search Google Scholar
• Export Citation

Voges GE, Tauschke E, Stockle M et al.. Computerized tomography: an unreliable method for accurate staging of bladder tumors in patients who are candidates for radical cystectomy. J Urol 1989;142:972–974.

VogesGETauschkeEStockleM. Computerized tomography: an unreliable method for accurate staging of bladder tumors in patients who are candidates for radical cystectomy. J Urol 1989;142:972–974. )| false
• Search Google Scholar
• Export Citation

Herr HW, Bochner BH, Dalbagni G et al.. Impact of the number of lymph nodes retrieved on outcome in patients with muscle invasive bladder cancer. J Urol 2002;167:1295–1298.

HerrHWBochnerBHDalbagniG. Impact of the number of lymph nodes retrieved on outcome in patients with muscle invasive bladder cancer. J Urol 2002;167:1295–1298. )| false
• Search Google Scholar
• Export Citation

Stein JP, Cai J, Groshen S et al.. Risk factors for patients with pelvic lymph node metastases following radical cystectomy with en bloc pelvic lymphadenectomy: concept of lymph node density. J Urol 2003;170:35–41.

SteinJPCaiJGroshenS. Risk factors for patients with pelvic lymph node metastases following radical cystectomy with en bloc pelvic lymphadenectomy: concept of lymph node density. J Urol 2003;170:35–41. )| false
• Search Google Scholar
• Export Citation

Herr HW. Superiority of ratio based lymph node staging for bladder cancer. J Urol 2003;169:943–945.

HerrHW. Superiority of ratio based lymph node staging for bladder cancer. J Urol 2003;169:943–945. )| false
• Search Google Scholar
• Export Citation

Herr H, Lee C, Chang S et al.. Standardization of radical cystectomy and pelvic lymph node dissection for bladder cancer: a collaborative group report. J Urol 2004;171:1823–1828; discussion 1827–1828.

HerrHLeeCChangS. Standardization of radical cystectomy and pelvic lymph node dissection for bladder cancer: a collaborative group report. J Urol 2004;171:1823–1828; discussion 1827–1828. )| false
• Search Google Scholar
• Export Citation

Koppie T, Vickers A, Vora K et al.. Standardization of pelvic lymphadenectomy performed at radical cystectomy: can we establish a minimum number of lymph nodes that should be removed? Cancer 2006; in press.

KoppieTVickersAVoraK. Standardization of pelvic lymphadenectomy performed at radical cystectomy: can we establish a minimum number of lymph nodes that should be removed? Cancer 2006; in press. )| false
• Search Google Scholar
• Export Citation

Fleischmann A, Thalmann GN, Markwalder R et al.. Extracapsular extension of pelvic lymph node metastases from urothelial carcinoma of the bladder is an independent prognostic factor. J Clin Oncol 2005;23:2358–2365.

FleischmannAThalmannGNMarkwalderR. Extracapsular extension of pelvic lymph node metastases from urothelial carcinoma of the bladder is an independent prognostic factor. J Clin Oncol 2005;23:2358–2365. )| false
• Search Google Scholar
• Export Citation

Schultz PK, Herr HW, Zhang ZF et al.. Neoadjuvant chemotherapy for invasive bladder cancer: prognostic factors for survival of patients treated with M-VAC with 5-year follow-up. J Clin Oncol 1994;12:1394–1401.

SchultzPKHerrHWZhangZF. Neoadjuvant chemotherapy for invasive bladder cancer: prognostic factors for survival of patients treated with M-VAC with 5-year follow-up. J Clin Oncol 1994;12:1394–1401. )| false
• Search Google Scholar
• Export Citation

Bajorin DF, Dodd PM, Mazumdar M et al.. Long-term survival in metastatic transitional-cell carcinoma and prognostic factors predicting outcome of therapy. J Clin Oncol 1999;17:3173–3181.

BajorinDFDoddPMMazumdarM. Long-term survival in metastatic transitional-cell carcinoma and prognostic factors predicting outcome of therapy. J Clin Oncol 1999;17:3173–3181. )| false
• Search Google Scholar
• Export Citation

Dimopoulos MA, Finn L, Logothetis CJ. Pattern of failure and survival of patients with metastatic urothelial tumors relapsing after cis-platinum-based chemotherapy. J Urol 1994;151:598–600; discussion 600–601.

DimopoulosMAFinnLLogothetisCJ. Pattern of failure and survival of patients with metastatic urothelial tumors relapsing after cis-platinum-based chemotherapy. J Urol 1994;151:598–600; discussion 600–601. )| false
• Search Google Scholar
• Export Citation

Dodd PM, McCaffrey JA, Herr H et al.. Outcome of postchemotherapy surgery after treatment with methotrexate, vinblastine, doxorubicin, and cisplatin in patients with unresectable or metastatic transitional cell carcinoma. J Clin Oncol 1999;17:2546–2552.

DoddPMMcCaffreyJAHerrH. Outcome of postchemotherapy surgery after treatment with methotrexate, vinblastine, doxorubicin, and cisplatin in patients with unresectable or metastatic transitional cell carcinoma. J Clin Oncol 1999;17:2546–2552. )| false
• Search Google Scholar
• Export Citation

Herr HW, Donat SM, Bajorin DF. Post-chemotherapy surgery in patients with unresectable or regionally metastatic bladder cancer. J Urol 2001;165:811–814.

HerrHWDonatSMBajorinDF. Post-chemotherapy surgery in patients with unresectable or regionally metastatic bladder cancer. J Urol 2001;165:811–814. )| false
• Search Google Scholar
• Export Citation

Mathiesen O, Carl J, Bonderup O et al.. Axillary sampling and the risk of erroneous staging of breast cancer. An analysis of 960 consecutive patients. Acta Oncol 1990;29:721–725.

MathiesenOCarlJBonderupO. Axillary sampling and the risk of erroneous staging of breast cancer. An analysis of 960 consecutive patients. Acta Oncol 1990;29:721–725. )| false
• Search Google Scholar
• Export Citation

Caplin S, Cerottini JP, Bosman FT et al.. For patients with Dukes' B (TNM Stage II) colorectal carcinoma, examination of six or fewer lymph nodes is related to poor prognosis. Cancer 1998;83:666–672.

CaplinSCerottiniJPBosmanFT. For patients with Dukes' B (TNM Stage II) colorectal carcinoma, examination of six or fewer lymph nodes is related to poor prognosis. Cancer 1998;83:666–672. )| false
• Search Google Scholar
• Export Citation

Siewert JR, Bottcher K, Stein HJ et al.. Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study. Ann Surg 1998;228:449–461.

SiewertJRBottcherKSteinHJ. Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study. Ann Surg 1998;228:449–461. )| false
• Search Google Scholar
• Export Citation