To Dream the Possible Dream

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Rodger J. Winn
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Rodger J. Winn is the Editor-in-Chief of JNCCN. His past positions include Associate Professor of Clinical Medicine at the University of Texas M. D. Anderson Cancer Center. Dr. Winn received his medical degree from Jefferson Medical College of Philadelphia. His postgraduate training includes an internship and residency at Jefferson Medical College, and he also completed a medical oncology fellowship at Memorial Sloan-Kettering Cancer Center in New York. He is board certified in internal medicine and holds subspecialty certification in oncology.

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  • 1

    Jemal A, Murray T, Ward E et al.. Cancer statistics, 2005. CA Cancer J Clin 2005;55:1030.

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    Demetri GC, vonMehren M, Blanke CD et al.. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 2002;347:472480.

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    Demetri GD, Benjamin R, Blanke CD et al.. NCCN Task Force Report: Optimal Management of Patients with Gastrointestinal Stromal Tumor (GIST) — Expansion and Update of NCCN Clinical Practice Guidelines. JNCCN 2004; 2[Suppl 1]: S-1S-26.

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  • 4

    Sawyers CL. Imatinib GIST keeps finding new indications: Successful treatment of dermatofibrosarocoma protuberans by targeted inhibition of the platelet-derived growth factor receptor. J Clin Oncol 2002;20:35683569.

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  • 5

    Rubin BP, Schuetze SM, Eary JF et al.. Molecular targeting of platelet derived growth factor by imatinib mesylate in a patient with metastatic dermatofibrosarcoma protuberans. J Clin Oncol 2002;20:35863591.

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  • 6

    Joensuu H, Roberts PJ, Sarlomo-Rikala M et al.. Effect of tyrosine kinase inhibitor ST1571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med 2001;344:10521056.

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  • 7

    Tejeda HA, Green SB, Trimble EL et al.. Representation of African-Americans, Hispanics, and whites in National Cancer Institute cancer treatment trials. J Nat Cancer Inst 1996;88:812816.

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  • 8

    Buchkowsky SS, Jewesson PJ. Industry sponsorship and authorship of clinical trials over 20 years. Ann Pharmacother 2004;38:714716.

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    Hillner BE. Trends in clinical trials reports in common cancers between 1989–2000. J Clin Oncol 2003;21:18501858.

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    Petrioli R, Coratti A, Correale P et al.. Adjuvant epirubicin with or without ifosfamide for adult soft-tissue sarcoma. Am J Clin Oncol 2002;25:468473.

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    Lara PN, Higdon R, Lim N et al.. Prospective evaluation of cancer clinical trial accrual patterns: identifying potential barriers to enrollment. J Clin Oncol 2001;19:17281733.

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  • 12

    Winn RJ. Obstacles to the accrual of patients to clinical trials in the community setting. Semin Oncol 1994;21(Suppl 7):112117.

  • 13

    Comis RLl, Miller JD, Aldige CR et al.. Public attitudes toward participation in cancer clinical trials. J Clin Oncol 2003;21:830835.

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    Martel CL, Beckett L, Chew H et al.. An evaluation of barriers to accrual in the era of legislation requiring insurance coverage of cancer clinical trials in California. Cancer J 2004;10:294300.

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  • 15

    Bennett CL, Adams JR, Knox KS et al.. Clinical trials: are they a good buy? J Clin Oncol 2001;19:43304339.

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    Cohen GI. Clinical research by community oncologists. CA Cancer J Clin 2003;53:7381.

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    Taylor KM, Feldstein ML, Skeel RT et al.. Fundamental dilemmas of the randomized clinical trial process: results of a survey of the 1,737 Eastern Cooperative Oncology Group investigators. J Clin Oncol 1994;12:17961805.

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  • 18

    Taylor KM, Margolese RG, Soskolne CL. Physicians' reasons for not entering eligible patients in a randomized clinical trial for surgery for breast cancer. N Engl J Med 1984;310:13631367.

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  • 19

    Emanuel EJ, Schnipper LE, Kamin DY et al.. The costs of conducting clinical research. J Clin Oncol 2003;21:41454150.

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    Batshaw ML, Plotnick LP, Petty BG et al.. Academic promotion at a medical school. Experience at Johns Hopkins University School of Medicine. N Engl J Med 1988;318:741747.

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