The NCCN Oncology Research Program (ORP) strives to improve the quality of life for patients and reduce cancer-related deaths by advancing cancer therapies through research. Since the program’s establishment in 1999, the NCCN ORP has brought millions of dollars in research grants to investigators at NCCN Member Institutions. Research grants are provided to NCCN through collaborations with pharmaceutical and biotechnology companies; these grants are in turn used to support scientifically meritorious cancer research efforts.
NCCN ORP studies typically explore new avenues of clinical investigation and seek answers to important cancer-related questions. All studies are approved and funded through a scientific peer-review process and are overseen by the ORP.
This feature highlights an NCCN study funded through the grant mechanism.
The Cardiovascular Risk Evaluation in Men with Prostate Cancer Study (CARE-PC): Pilot Feasibility Study to Assess Patient Awareness and Risk Mitigation
Principal Investigator: Vivek Narayan, MD, MSCE
Condition: Prostate cancer/quality study
Institution: University of Pennsylvania, Abramson Cancer Center
The overarching goal of this trial is to develop mechanisms to improve cardiovascular (CV) care among patients with prostate cancer receiving androgen deprivation therapy (ADT) by increasing patient awareness of individualized CV risk estimates and personalized CV risk mitigation opportunities. Patients will be provided access to a web-based quality improvement tool to educate patients of CV risks in prostate cancer and to inform them of their individualized, estimated CV risk and guideline-based risk mitigation recommendations.
The study will assess the feasibility of this web-based application as a CV education tool for patients with prostate cancer receiving and/or initiating ADT.
The study will also evaluate if completion of the web-based tool improves CV care access and utilization of CV risk–reducing medications for patients with prostate cancer.
Primary Objective/Aim:
• Evaluate the feasibility and acceptability of a pragmatic, patient-oriented, web-based application that enables the education of patients regarding CV risks and collects CV and prostate cancer–related risk variables and CV care access data from patients with prostate cancer receiving ADT
Secondary Objectives/Aims:
• Evaluate the data quality of the web-based application among patients with prostate cancer receiving ADT
• Preliminarily assess the impact of the web-based application on CV care access and risk mitigation among men with prostate cancer receiving ADT
Contact: Matthew Doyle • matthew.doyle@pennmedicine.upenn.edu
Vivek Narayan, MD, MSCE • VNarayan@pennmedicine.upenn.edu
ClinicalTrials.gov Identifier: NCT06064149
