Biobehavioral Factors in Chemotherapy-Induced Nausea and Vomiting

Authors:
Joseph A. Roscoe Cancer Control Program, James P. Wilmot Cancer Center, University of Rochester Medical Center, Rochester, New York

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 PhD
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Gary R. Morrow Cancer Control Program, James P. Wilmot Cancer Center, University of Rochester Medical Center, Rochester, New York

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Jane T. Hickok Cancer Control Program, James P. Wilmot Cancer Center, University of Rochester Medical Center, Rochester, New York

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Karen M. Mustian Cancer Control Program, James P. Wilmot Cancer Center, University of Rochester Medical Center, Rochester, New York

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Abhay R. Shelke Cancer Control Program, James P. Wilmot Cancer Center, University of Rochester Medical Center, Rochester, New York

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Volume/Issue:
Volume 2: Issue 5
Online Publication Date:
Sep 2004
DOI:
https://doi.org/10.6004/jnccn.2004.0039
Full access

Although emesis can be considered a reflex to clear toxins from the body and involves mostly lower brain structures, nausea's purpose appears to be a warning signal to the individual to not engage in behaviors that he or she was doing at the time. As such, it involves the functioning of cognition and memory from higher developed neural structures. Given this, it should not be surprising that biobehavioral factors are important in predicting and controlling nausea. This article reviews the individual characteristics that are clinically useful in predicting which patients will have an increased probability of experiencing nausea or emesis during chemotherapy treatment, and also briefly review psychologic and biobehavioral treatments that can be useful in managing chemotherapy-related nausea.

Correspondence: Joseph Roscoe, PhD, University of Rochester Cancer Center, 601 Elmwood Avenue, Box 704, Rochester, New York 14642. E-mail: Joseph_Roscoe@urmc.rochester.edu
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Copyright:
Copyright © 2004 by the National Comprehensive Cancer Network 2004
Page Numbers:
8
Article Category:
Research Article
Received:
19 May 2004
Accepted:
12 Jul 2004
Print Publication Date:
01 Sep 2004
Online Publication Date:
Sep 2004
Keywords:
Nausea; emesis; chemotherapy; biobehavioral; expectancy
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