Multiple Myeloma Clinical Practice Guidelines in Oncology

Multiple myeloma will account for an estimated 15,270 (1.1%) new cancer cases in the United States in the year 2004, including 8,090 cases in men (1.2%) and 7,180 (1.1%) cases in women. It will also be responsible for approximately 11,070 (2.0%) cancer deaths in 2004. Although multiple myeloma is sensitive to both chemotherapy and radiation therapy, it remains incurable at present. However, treatment algorithms such as this one (based on published data and clinical experience) can optimize therapy, not only for the underlying disease but also supportive therapy to enhance quality of life. Because myeloma is incurable, these guidelines prominently identify the clinical settings appropriate for treatment of patients on clinical research protocols.

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