NIH: Grants & Funding. NIH’s definition of a clinical trial. Available at: https://grants.nih.gov/policy/clinical-trials/definition.htm. Accessed January 16, 2019.
National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines). Available at: NCCN.org. Accessed September 13, 2019.
Murthy VH, Krumholz HM, Gross CP. Participation in cancer clinical trials: race-, sex-, and age-based disparities. JAMA 2004;291:2720–2726.
Lara PN Jr, Higdon R, Lim N, et al.. Prospective evaluation of cancer clinical trial accrual patterns: identifying potential barriers to enrollment. J Clin Oncol 2001;19:1728–1733.
Peppercorn JM, Weeks JC, Cook EF, et al.. Comparison of outcomes in cancer patients treated within and outside clinical trials: conceptual framework and structured review. Lancet 2004;363:263–270.
von Elm E, Altman DG, Egger M, et al.. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol 2008;61:344–349.
Boffa DJ, Rosen JE, Mallin K, et al.. Using the National Cancer Database for outcomes research: a review. JAMA Oncol 2017;3:1722–1728.
American College of Surgeons. National Cancer Database. Participant User Files. Available at: https://www.facs.org/quality-programs/cancer/ncdb/puf. Accessed October 5, 2019.
Bleyer A. In and out, good and bad news, of generalizability of SWOG treatment trial results. J Natl Cancer Inst 2014;106:dju027.
Wood WA, Lee SJ. Malignant hematologic diseases in adolescents and young adults. Blood 2011;117:5803–5815.
Hay AE, Rae C, Fraser GA, et al.. Accrual of adolescents and young adults with cancer to clinical trials. Curr Oncol 2016;23:e81–85.
Wuthrick EJ, Zhang Q, Machtay M, et al.. Institutional clinical trial accrual volume and survival of patients with head and neck cancer. J Clin Oncol 2015;33:156–164.
Arrieta O, Carmona A, Ramírez-Tirado LA, et al.. Survival of patients with advanced non-small cell lung cancer enrolled in clinical trials. Oncology 2016;91:185–193.
Chow CJ, Habermann EB, Abraham A, et al.. Does enrollment in cancer trials improve survival? J Am Coll Surg 2013;216:774–780, discussion 780–781.
Ohri N, Shen X, Dicker AP, et al.. Radiotherapy protocol deviations and clinical outcomes: a meta-analysis of cooperative group clinical trials. J Natl Cancer Inst 2013;105:387–393.
Temel JS, Greer JA, Muzikansky A, et al.. Early palliative care for patients with metastatic non-small-cell lung cancer. N Engl J Med 2010;363:733–742.
Unger JM, Barlow WE, Martin DP, et al.. Comparison of survival outcomes among cancer patients treated in and out of clinical trials. J Natl Cancer Inst 2014;106:dju002.