New treatment pathways for giant cell tumor of bone (GCTB) and chordoma make their debut in the updated version of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for bone cancer, joining those for osteosarcoma, nonmetastatic Ewing’s sarcoma, and chondrosarcoma. Guidelines for managing these bone cancers are especially important, given the rarity of these neoplasms and most clinicians’ lack of familiarity with them, said J. Sybil Biermann, MD, Professor and Medical Director of the Sarcoma Program at the University of Michigan Comprehensive Cancer Center in Ann Arbor, and Chair of the NCCN Guidelines Panel on Bone Cancer. Although metastatic osteosarcoma was also newly added to the guidelines, it was not included in Dr. Biermann’s presentation, as it generally follows the previous recommendations for osteosarcoma.
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