With photodynamic therapy (PDT), clinicians often forget that it is not just the drug and the light that are important but also how tissue oxygen is managed, stated Gary S. Rogers, MD, Director, Dermatologic Surgery & Oncology, Tufts University School of Medicine, Tufts Medical Center, Boston, Massachusetts. “How we administer the energy will determine whether you get tumor apoptosis, tumor necrosis, exactly which vasculature you are going to affect, and how you will affect the immune system by giving the light at a lower dose,” he explained.
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