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Wui-Jin Koh, Benjamin E. Greer, Nadeem R. Abu-Rustum, Sachin M. Apte, Susana M. Campos, Kathleen R. Cho, Christina Chu, David Cohn, Marta Ann Crispens, Don S. Dizon, Oliver Dorigo, Patricia J. Eifel, Christine M. Fisher, Peter Frederick, David K. Gaffney, Suzanne George, Ernest Han, Susan Higgins, Warner K. Huh, John R. Lurain III, Andrea Mariani, David Mutch, Amanda Nickles Fader, Steven W. Remmenga, R. Kevin Reynolds, Todd Tillmanns, Fidel A. Valea, Catheryn M. Yashar, Nicole R. McMillian and Jillian L. Scavone

, participants will be able to: Integrate into professional practice the updates to the NCCN Guidelines for Uterine Sarcoma Describe the rationale behind the decision-making process for developing the NCCN Guidelines for Uterine Sarcoma NCCN

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Benjamin E. Greer, Wui-Jin Koh, Nadeem Abu-Rustum, Michael A. Bookman, Robert E. Bristow, Susana M. Campos, Kathleen R. Cho, Larry Copeland, Marta Ann Crispens, Patricia J. Eifel, Warner K. Huh, Wainwright Jaggernauth, Daniel S. Kapp, John J. Kavanagh, John R. Lurain III, Mark Morgan, Robert J. Morgan Jr, C. Bethan Powell, Steven W. Remmenga, R. Kevin Reynolds, Angeles Alvarez Secord, William Small Jr and Nelson Teng

. 2 Olah K Gee H Blunt S . Retrospective analysis of 318 cases of uterine sarcoma . Eur J Cancer 1991 ; 27 : 1095 – 1099 . 3 Ueda SM Kapp DS Cheung MK . Trends in demographic and clinical characteristics in women diagnosed with

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Wui-Jin Koh, Benjamin E. Greer, Nadeem R. Abu-Rustum, Sachin M. Apte, Susana M. Campos, John Chan, Kathleen R. Cho, David Cohn, Marta Ann Crispens, Nefertiti DuPont, Patricia J. Eifel, Amanda Nickles Fader, Christine M. Fisher, David K. Gaffney, Suzanne George, Ernest Han, Warner K. Huh, John R. Lurain III, Lainie Martin, David Mutch, Steven W. Remmenga, R. Kevin Reynolds, William Small Jr, Nelson Teng, Todd Tillmanns, Fidel A. Valea, Nicole McMillian and Miranda Hughes

will occur in 2013, with 8190 deaths resulting from the disease. 1 Uterine sarcomas (stromal/mesenchymal tumors) are uncommon malignancies, accounting for approximately 3% of all uterine cancers. 2 The NCCN Clinical Practice Guidelines in Oncology

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Wui-Jin Koh, Nadeem R. Abu-Rustum, Sarah Bean, Kristin Bradley, Susana M. Campos, Kathleen R. Cho, Hye Sook Chon, Christina Chu, David Cohn, Marta Ann Crispens, Shari Damast, Oliver Dorigo, Patricia J. Eifel, Christine M. Fisher, Peter Frederick, David K. Gaffney, Suzanne George, Ernest Han, Susan Higgins, Warner K. Huh, John R. Lurain III, Andrea Mariani, David Mutch, Christa Nagel, Larissa Nekhlyudov, Amanda Nickles Fader, Steven W. Remmenga, R. Kevin Reynolds, Todd Tillmanns, Stefanie Ueda, Emily Wyse, Catheryn M. Yashar, Nicole R. McMillian and Jillian L. Scavone

Uterine Neoplasms describe malignant epithelial tumors and uterine sarcomas; each of these major categories contains specific histologic groups that require different management (see “Initial Clinical Findings” in the NCCN Guidelines for Uterine Neoplasms

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Lauren E. Kernochan and Rochelle L. Garcia

Edited by Kerrin G. Robinson

adenocarcinomas . Am J Clin Pathol 2004 ; 122 : 546 – 551 . 32 Jeffers MD Richmond JA Macaulay EM . Overexpression of the c-myc proto-oncogene occurs frequently in uterine sarcomas . Mod Pathol 1995 ; 8 : 701 – 704 . 33 Fujii H Yoshida

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Ungarreevittaya Piti c d MD Nelson Scott D. c MD Chawla Sant P. e MD Singh Arun S. f MD 11 2015 13 13 11 11 1310 1310 1314 1314 0131310 10.6004/jnccn.2015.0161 Uterine Sarcoma, Version 1.2016 Koh Wui-Jin 1 MD/Co-Chair Greer

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Srinivas K. Tantravahi, and Theresa L. Werner

-based analysis, 4% of the endometrial cancers occurred in women aged 40 years or younger. 4 Endometrial cancer includes epithelial and nonepithelial tumors, such as sarcomas. Uterine sarcomas are highly aggressive and rare tumors, accounting for approximately 3

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Irene Dy, Rangaswamy Chintapatla, Isabel Preeshagul and Daniel Becker

response of the underlying cancer to therapy and visual abnormalities. Eltabbakh et al 5 reported on a 65-year-old woman with uterine sarcoma whose CAR resolved after surgical debulking and chemotherapy. Sekiguchi et al, 6 however, reported on a 60-year

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rising for the most common type of uterine cancer—endometrial cancer. The newest NCCN Guidelines for Patients focuses on uterine cancers (endometrial cancer and a much rarer type called uterine sarcoma). Uterine cancers are by far the most prevalent type

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Andrew Wagner

triazenoimidazole carboxamide in advanced uterine sarcomas . Cancer 1983 ; 52 : 626 – 632 . 30. Elias A Ryan L Sulkes A . Response to mesna, doxorubicin, ifosfamide, and dacarbazine in 108 patients with metastatic or unresectable sarcoma and no prior