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John Fanikos and Samuel Z. Goldhaber

Haire WD Feldstein ML . Alteplase versus heparin in acute pulmonary embolism: randomised trial assessing right-ventricular function and pulmonary perfusion . Lancet 1993 ; 341 : 501 – 511 . 55. Wan S Quinlan DJ Agnelli G . Thrombolysis

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Gerald A. Soff

of rivaroxaban for treatment of cancer-associated venous thromboembolic disease: a prospective cohort study. J Thromb Thrombolysis 2017;43:166–171. could be someone who was post-gastrectomy, or had nephrostomy or urostomy tubes, any kind of

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Michael B. Streiff

for deep vein thrombosis and pulmonary embolism: a population-based case-control study . Arch Intern Med 2000 ; 160 : 809 – 815 . 2. Deitcher SR . Cancer and thrombosis: mechanisms and treatment . J Thromb Thrombolysis 2003 ; 16 : 21

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Myron Goldsmith, George Whitelaw and Denise A. Cannaday

. Electronic alerts for hospitalized high-VTE risk patients not receiving prophylaxis: a cohort study . J Thromb Thrombolysis 2008 ; 25 : 146 – 150 . 7. Health Grades, Inc. The Fifth Annual HealthGrades Patient Safety in American Hospitals Study

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Michael L. Linenberger

. 105. Frank DA Meuse J Hirsch D . The treatment and outcome of cancer patients with thromboses on central venous catheters . J Thromb Thrombolysis 2000 ; 10 : 271 – 275 . 106. Hingorani A Ascher E Lorenson E . Upper extremity deep

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Jeffrey A. Kline and David W. Miller

Scalzo S Maringhini G . Six-month echocardiographic study in patients with submassive pulmonary embolism and right ventricle dysfunction: comparison of thrombolysis with heparin . Am J Med Sci 2011 ; 341 : 33 - 39 . 80 Crowther MA Berry LR

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Erin R. Weeda, Jonathan T. Caranfa, Simon B. Zeichner, Craig I. Coleman, Elaine Nguyen and Christine G. Kohn

high-risk group that requires more aggressive care and a low-risk group that may qualify for deescalation of treatment, biomarkers and imaging were originally studied to identify patients with PE who might benefit from thrombolysis and embolectomy. 21

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Michael B. Streiff, Paula L. Bockenstedt, Spero R. Cataland, Carolyn Chesney, Charles Eby, John Fanikos, Patrick F. Fogarty, Shuwei Gao, Julio Garcia-Aguilar, Samuel Z. Goldhaber, Hani Hassoun, Paul Hendrie, Bjorn Holmstrom, Kimberly A. Jones, Nicole Kuderer, Jason T. Lee, Michael M. Millenson, Anne T. Neff, Thomas L. Ortel, Judy L. Smith, Gary C. Yee and Anaadriana Zakarija

nature. Rarely, this method is combined with catheter-directed thrombectomy or thrombolysis. These measures should be planned before and executed simultaneously with conventional pulmonary angiography. Fatality caused by PE primarily occurs through

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Michael B. Streiff, Bjorn Holmstrom, Aneel Ashrani, Paula L. Bockenstedt, Carolyn Chesney, Charles Eby, John Fanikos, Randolph B. Fenninger, Annemarie E. Fogerty, Shuwei Gao, Samuel Z. Goldhaber, Paul Hendrie, Nicole Kuderer, Alfred Lee, Jason T. Lee, Mirjana Lovrincevic, Michael M. Millenson, Anne T. Neff, Thomas L. Ortel, Rita Paschal, Sanford Shattil, Tanya Siddiqi, Kristi J. Smock, Gerald Soff, Tzu-Fei Wang, Gary C. Yee, Anaadriana Zakarija, Nicole McMillian and Anita M. Engh

Risk Manag 2015 ; 11 : 153 – 160 . 54. Leung A Heal C Perera M Pretorius C . A systematic review of patient-related risk factors for catheter-related thrombosis . J Thromb Thrombolysis 2015 ; 40 : 363 – 373 . 55. Blaivas M

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Michael B. Streiff, Bjorn Holmstrom, Dana Angelini, Aneel Ashrani, Paula L. Bockenstedt, Carolyn Chesney, John Fanikos, Randolph B. Fenninger, Annemarie E. Fogerty, Shuwei Gao, Samuel Z. Goldhaber, Krishna Gundabolu, Paul Hendrie, Alfred I. Lee, Jason T. Lee, Janelle Mann, Brandon McMahon, Michael M. Millenson, Colleen Morton, Thomas L. Ortel, Sadat Ozair, Rita Paschal, Sanford Shattil, Tanya Siddiqi, Kristi J. Smock, Gerald Soff, Tzu-Fei Wang, Eliot Williams, Anaadriana Zakarija, Lydia Hammond, Mary A. Dwyer and Anita M. Engh

-Perdomo HA . Risk of intracranial hemorrhage associated with therapeutic anticoagulation for venous thromboembolism in cancer patients: a systematic review and meta-analysis . J Thromb Thrombolysis 2017 ; 43 : 233 – 240 . 11. Kahale