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Bryan J. Schneider, Ashish Saxena and Robert J. Downey

Committee recommended that the TNM staging system be used to stage SCLC in both routine practice and clinical trial design. 4 The standard treatment for LS-SCLC is definitive chemoradiation therapy without surgery; however, whether surgery has a role in

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Benjamin E. Greer, Ron E. Swensen and Heidi J. Gray

experience . J Clin Oncol 1991 ; 9 : 1138 – 1150 . 19 Hacker NF Berek JS Lagasse LD . Primary cytoreductive surgery for epithelial ovarian cancer . Obstet Gynecol 1983 ; 61 : 413 – 420 . 20 Hoskins WJ Bundy BN Thigpen JT . The

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Robert J. Downey and Lee M. Krug

. Philadelphia, PA : Lippincott Williams and Wilkins , 2000 . 2 Passlick B . Can surgery improve local control in small cell lung cancer? Lung Cancer 2001 ; 33 ( Suppl 1 ): S147 – S151 . 3 Kohman LJ . Is there a place for surgery in

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David Y. T. Chen and Robert G. Uzzo

Edited by Kerrin G. Robinson

Viterbo R Greenberg RE Al-Saleem T Uzzo RG . Prior abdominal surgery and radiation do not complicate the retroperitoneoscopic approach to the kidney or adrenal gland . J Urol 2005 ; 174 : 446 – 450 . 14 Nelson CP Wolf JS Jr . Comparison

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Michael J. Hassett, Wei Jiang, Melissa E. Hughes, Stephen Edge, Sara H. Javid, Joyce C. Niland, Richard Theriault, Yu-Ning Wong, Deborah Schrag and Rinaa S. Punglia

As the incidence of ductal carcinoma in situ (DCIS) has increased, so has the number of DCIS survivors. 1 Most patients with DCIS are treated with breast-conserving surgery (BCS). 2 Radiation therapy (RT) and antiestrogen therapy (AET) have been

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Kathryn P. Pennington, Renata R. Urban and Heidi J. Gray

Use of minimally invasive surgery (MIS) in the management of early-stage cervical cancer (ESCC), previously considered an acceptable alternative to open surgery, 1 was recently challenged by results of the Laparoscopic Approach to Cervical

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Ashwin Shinde, Richard Li, Arya Amini, Yi-Jen Chen, Mihaela Cristea, Wenge Wang, Mark Wakabyashi, Ernest Han, Catheryn Yashar, Kevin Albuquerque, Sushil Beriwal and Scott Glaser

Cancer suggest consideration of radiation therapy (RT) with concurrent chemotherapy in larger T2 or T3 lesions not amenable to up-front organ-sparing surgery. 3 However, minimal published data, either retrospective or prospective, exists for patients

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Alfredo A. Santillan, Jeffrey M. Farma, Kenneth L. Meredith, Nilay R. Shah and Scott T. Kelley

, 2007 . CA Cancer J Clin 2007 ; 57 : 43 – 66 . 3. Kelsen DP Ginsberg R Pajak TF . Chemotherapy followed by surgery compared with surgery alone for localized esophageal cancer . N Engl J Med 1998 ; 339 : 1979 – 1984 . 4

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Richard Li, Ashwin Shinde, Marwan Fakih, Stephen Sentovich, Kurt Melstrom, Rebecca Nelson, Scott Glaser, Yi-Jen Chen, Karyn Goodman and Arya Amini

recommendations. No randomized trials exist, and the results of small retrospective case series have led to contradictory conclusions. A study by the Rare Cancer Network showed improved survival with CRT alone compared with surgery/radiotherapy (RT) or surgery

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Stephen B. Edge

clinical trials. Early trials showed that extended surgery (“local therapy”) does not improve mortality over less aggressive surgery. Trials conducted in the 1970s and 1980s clearly showed that radical surgery involving removal of the breast provides no