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Catriona Parker, Raymond Snyder, Michael Jefford, David Dilts, Rory Wolfe and Jeremy Millar

. In 1999, a systematic review identified factors limiting the quality, number, and progress of randomized controlled trials (RCTs). 1 Recruitment was identified as one of these factors, and participation barriers were classified as clinician

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Nawin Kuntaraksa

formation. Materials and Methods: A randomized control trial was conducted between January 2014 and November 2017. 68 consecutive patients undergoing mastectomy with axillary lymph node dissection by one experienced surgeon. The patients were randomly

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Thomas W. LeBlanc and Amy P. Abernethy

evidence base to guide interventions and practice. This article focuses on the issue of evidence base development in palliative cancer care, using the example of a recently published randomized controlled trial of a commonly used palliative intervention

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Kerry Schaffer, Narmadha Panneerselvam, Kah Poh Loh, Rachel Herrmann, Ian R. Kleckner, Richard Francis Dunne, Po-Ju Lin, Charles E. Heckler, Nicholas Gerbino, Lauren B. Bruckner, Eugene Storozynsky, Bonnie Ky, Andrea Baran, Supriya Gupta Mohile, Karen Michelle Mustian and Chunkit Fung

behavior change intervention: randomized controlled trial . J Med Internet Res 2014 ; 16 : e54 . 31. Haggerty AF Huepenbecker S Sarwer DB . The use of novel technology-based weight loss interventions for obese women with endometrial

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Kyaw Z. Thein, Sriman Swarup, Anita Sultan, Subhanudh Thavaraputta, Myo H. Zaw, Nicholas D’Cunha, Sanjay Awasthi, Fred Hardwicke and Lukman Tijani

, there are notable toxicities. We performed a systematic review and meta-analysis of randomized controlled trials (RCT) to determine the risk of palmar-plantar erythrodysesthesia (PPE) and hypertension in patients with metastatic solid tumors treated with

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Anita Sultan, Sriman Swarup, Francis Mogollon-Duffo, Ye Aung, Yin M. Myat, Myo H. Zaw, Rachana Yendala, Nicholas D’Cunha and Kyaw Z. Thein

. These pathways are implicated in several tumor development and progression. We performed a systematic review and meta-analysis of randomized controlled trials (RCT) to determine the risk of gastrointestinal (GI) and hepatic toxicities among patients with

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Davide Mauri, Antonis Valachis, Nikolaos P. Polyzos, Lamprini Tsali, Dimitris Mavroudis, Vassilis Georgoulias and Giovanni Casazza

Many randomized controlled trials have evaluated the role of bisphosphonates in the adjuvant setting of breast cancer and have shown a beneficial effect on bone loss prevention. 9 However, the overall clinical impact of bisphosphonates on the disease

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Giovambattista Zeppetella

analgesia. This article describes the randomized controlled trials that have led to the support of the use of transmucosal fentanyl therapies for BTPc, starting in 1999 with oral transmucosal fentanyl citrate (OTFC) formulations through to the end of 2011

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Tarek Haykal, Babikir Kheiri, Varun Samji, Yazan Zayed, Ragheed Al-Dulaimi, Inderdeep Gakhal, Areeg Bala, Jason Sotzen, Ahmed Abdalla and Ghassan Bachuwa

-related AEs in a pooled analysis from all available randomized controlled trials (RCTs). Methods: A comprehensive electronic database search was conducted for all RCTs comparing the clinical outcomes and adverse events of sunitinib versus all other available

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Kyaw Z. Thein, Somedeb Ball, Sriman Swarup, Anita Sultan, Myo H. Zaw, Lukman Tijani, Sanjay Awasthi, Fred Hardwicke and Catherine Jones

, potential cardiac toxicities remain a concern. We undertook a combined analysis of randomized controlled trials (RCT) to estimate the incidence of prolongation of corrected QT interval (QTcF) associated with ribociclib. Methods: We performed systematic