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Timothy Paul Hanna, Geoffrey Paul Delaney and Michael Bernard Barton

Background Radiotherapy (RT) is vital to the management of primary malignant brain tumors. It has been estimated that 80% of patients with malignant brain tumors have an indication for RT because of superior local control (LC), survival, or

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Mary F. Mulcahy, Andrew O. Wahl and William Small Jr.

: 1705 – 1710 . 16 Gastrointestinal Tumor Study Group . Treatment of locally unresectable carcinoma of the pancreas: comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone . J Natl Cancer Inst 1988

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Roy H. Decker and Lynn D. Wilson

-cell carcinoma of the skin . Lancet Oncol 2004 ; 5 : 593 – 599 . 16. Veness MJ Perera L McCourt J . Merkel cell carcinoma: improved outcome with adjuvant radiotherapy . Aust N Z J Surg 2005 ; 75 : 275 – 281 . 17. Veness MJ . Merkel

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Hans Theodor Eich, Jan Kriz and Rolf-Peter Müller

Radiotherapy (RT) is a key modality in the treatment of Hodgkin lymphoma (HL), and clinical trials are increasing the understanding of its role in the management of this disease. The German Hodgkin Study Group (GHSG), based at the University of

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Daniel R. Simpson, Parag Sanghvi and Ajay P. Sandhu

Approximately 15% of these patients are diagnosed at an early stage, 1 but because of medical comorbidities, many of these patients are not candidates for surgical resection. Stereotactic body radiotherapy (SBRT) has been shown to be an excellent alternative to

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Michael D. Green and James A. Hayman

paucity of prospective randomized studies to guide clinical practice. This review explores the role of radiotherapy (RT) as part of the multimodality management of MCC and presents current areas of consensus and controversy. MCC arises from epidermal

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Matthew D. Callister and Leonard L. Gunderson

different advanced radiation therapy techniques in patients with gastric cancer Adjuvant Chemoradiation in Gastric Cancer The rationale and benefit of radiotherapy (RT) for managing nonmetastatic gastric and gastroesophageal junction (GEJ

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Puneeth Iyengar and Robert D. Timmerman

The concept of stereotactic ablative radiotherapy (SABR), known in older reports as stereotactic body radiation therapy (SBRT), for the treatment of lung cancer traces its roots back to the use of stereotactic radiosurgery in the treatment of

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Vivek Verma, Pamela K. Allen, Charles B. Simone II, Hiram A. Gay and Steven H. Lin

with unknown receipt of chemotherapy and/or radiotherapy (RT) were excluded, as were patients who did not undergo chemotherapy. For the purposes of this study, definitive RT referred to doses ≥60 Gy; although ≥66 Gy to gross disease is recommended, 21

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Michael Xiang and Elizabeth A. Kidd

, 12 and a meta-analysis 13 have shown that concurrent chemoradiation (CRT) increases survival compared with definitive radiotherapy (RT) alone, but the fraction of patients aged >65 years was only 6% to 7%. 13 This finding precludes drawing robust