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Timothy Paul Hanna, Geoffrey Paul Delaney, and Michael Bernard Barton

Background Radiotherapy (RT) is vital to the management of primary malignant brain tumors. It has been estimated that 80% of patients with malignant brain tumors have an indication for RT because of superior local control (LC), survival, or

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Vishruth K. Reddy, Varsha Jain, Sriram Venigalla, William P. Levin, Robert J. Wilson II, Kristy L. Weber, Anusha Kalbasi, Ronnie A. Sebro, and Jacob E. Shabason

factors were associated with RT use. Figure 1. Trends in receipt of surgery alone or surgery in addition to perioperative RT. Abbreviation: RT, radiation therapy. Table 1. Factors Associated With Receipt of Radiotherapy Factors Associated With Receipt of

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Mary F. Mulcahy, Andrew O. Wahl, and William Small Jr.

: 1705 – 1710 . 16 Gastrointestinal Tumor Study Group . Treatment of locally unresectable carcinoma of the pancreas: comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone . J Natl Cancer Inst 1988

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Roy H. Decker and Lynn D. Wilson

-cell carcinoma of the skin . Lancet Oncol 2004 ; 5 : 593 – 599 . 16. Veness MJ Perera L McCourt J . Merkel cell carcinoma: improved outcome with adjuvant radiotherapy . Aust N Z J Surg 2005 ; 75 : 275 – 281 . 17. Veness MJ . Merkel

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Hans Theodor Eich, Jan Kriz, and Rolf-Peter Müller

Radiotherapy (RT) is a key modality in the treatment of Hodgkin lymphoma (HL), and clinical trials are increasing the understanding of its role in the management of this disease. The German Hodgkin Study Group (GHSG), based at the University of

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Daniel R. Simpson, Parag Sanghvi, and Ajay P. Sandhu

Approximately 15% of these patients are diagnosed at an early stage, 1 but because of medical comorbidities, many of these patients are not candidates for surgical resection. Stereotactic body radiotherapy (SBRT) has been shown to be an excellent alternative to

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Michael D. Green and James A. Hayman

paucity of prospective randomized studies to guide clinical practice. This review explores the role of radiotherapy (RT) as part of the multimodality management of MCC and presents current areas of consensus and controversy. MCC arises from epidermal

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Matthew D. Callister and Leonard L. Gunderson

different advanced radiation therapy techniques in patients with gastric cancer Adjuvant Chemoradiation in Gastric Cancer The rationale and benefit of radiotherapy (RT) for managing nonmetastatic gastric and gastroesophageal junction (GEJ

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Soumyajit Roy, Paul Hoskins, Anna Tinker, Harinder Brar, Gale Bowering, and Gaurav Bahl

radiotherapy (RT) in this patient population. 10 – 12 RT has been explored as a salvage or adjuvant treatment option in OCCC. Retrospective studies have shown durable local control rates with salvage limited-field RT after first-line chemotherapy. 11 , 13 A

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Emily J. Martin, Andrew R. Bruggeman, Vinit V. Nalawade, Reith R. Sarkar, Edmund M. Qiao, Brent S. Rose, and James D. Murphy

provide rapid and durable relief of dysphagia and pain while minimizing the risk of toxicity. Multiple palliative treatment modalities are available for patients with metastatic esophageal cancer, though palliative radiotherapy (RT) to the esophagus and