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Jane Apperley

to have functions that may be important in gonadal development, implantation, and fetal development. 1 - 5 An international registry of pregnancy outcome was recently established by Novartis to compile pregnancy outcomes in women who have been

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Lauren Nye, Timothy K. Huyck, and William J. Gradishar

Breast cancer is the most common malignancy associated with pregnancy and is a rare but well-recognized complication. 1 A California registry study showed an incidence of 1.3 breast cancers diagnosed per 10,000 live births. 2 It is hypothesized

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Kevin M. Elias, Ross S. Berkowitz, and Neil S. Horowitz

pregnancy but may develop after any gestation. Molar Pregnancy: Complete Versus Partial CHM and PHM differ based on their chromosomal pattern, gross morphology, and histopathology ( Table 1 ). 5 CHM is generally diploid, and the molar chromosomes are

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Annika M. Gustafson, Deborah J. Goldfrank, William A. Dunson, Daniel L. Mulkerin, Rebecca L. Caires, and Keith D. Eaton

Unknowingly treating a pregnant patient is a preventable harm. Screening appropriate patient populations for pregnancy is a preventive measure that can help avoid this “never” event. Yet, pregnancy screening is not consistently integrated into

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Ellin Berman

%) received imatinib. Approximately one-quarter (n=38) received imatinib throughout pregnancy. The investigators reported 8 cases (5%) of congenital abnormalities, including craniosynostosis, hypoplastic lung, duplex kidneys, hemivertebrae, cerebellar

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Lindsey M. Charo, Adam M. Burgoyne, Paul T. Fanta, Hitendra Patel, Juliann Chmielecki, Jason K. Sicklick, and Michael T. McHale

adnexal mass. We also review the genomics of GIST, and present a novel tumor mutation to highlight the emerging importance of molecular profiling in dictating personalized cancer treatment, especially during pregnancy. Case A 34-year-old Hispanic G3P

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Grace Choong, Lisa E. Vaughan, Amy L. Weaver, Michelle Mielke, Wendy White, Andrea Kattah, and Vesna Garovic

Introduction: Breast cancer (BCa) is the second leading cause of cancer in women [1]. Estrogen exposure is an established risk factor for developing BCa. Hypertensive disorders of pregnancy (HDP) have been associated with hormonal changes that

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Arnel Pallera, Jessica K. Altman, Ellin Berman, Camille N. Abboud, Bhavana Bhatnagar, Peter Curtin, Daniel J. DeAngelo, Jason Gotlib, R. Tanner Hagelstrom, Gabriela Hobbs, Madan Jagasia, Hagop M. Kantarjian, Patricia Kropf, Leland Metheny, Joseph O. Moore, Evelena Ontiveros, Enkhtsetseg Purev, Albert Quiery, Vishnu V.B. Reddy, Michal G. Rose, Neil P. Shah, B. Douglas Smith, David S. Snyder, Kendra L. Sweet, Raoul Tibes, David T. Yang, Kristina Gregory, Hema Sundar, Michael Deininger, and Jerald P. Radich

. Management of Chronic Myeloid Leukemia During Pregnancy Tyrosine kinase inhibitor (TKI) therapy with small molecule inhibitors of BCR-ABL tyrosine kinase (imatinib, dasatinib, and nilotinib) is the standard first-line therapy for patients with newly

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Nadeem R. Abu-Rustum, Catheryn M. Yashar, Sarah Bean, Kristin Bradley, Susana M. Campos, Hye Sook Chon, Christina Chu, David Cohn, Marta Ann Crispens, Shari Damast, Oliver Dorigo, Patricia J. Eifel, Christine M. Fisher, Peter Frederick, David K. Gaffney, Ernest Han, Warner K. Huh, John R. Lurain III, Andrea Mariani, David Mutch, Christa Nagel, Larissa Nekhlyudov, Amanda Nickles Fader, Steven W. Remmenga, R. Kevin Reynolds, Rachel Sisodia, Todd Tillmanns, Stefanie Ueda, Emily Wyse, Nicole R. McMillian, and Jillian Scavone

diagnostic criteria, reporting practices, quality of epidemiologic data, and diet and nutrition. In the United States, the reported incidence of GTD is approximately one of every 1,000 pregnancies. 1 – 3 The most common form of GTD is hydatidiform mole (HM

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Peter F. Coccia, Alberto S. Pappo, Jessica Altman, Smita Bhatia, Scott C. Borinstein, Joseph Flynn, A. Lindsay Frazier, Suzanne George, Robert Goldsby, Robert Hayashi, Mary S. Huang, Rebecca H. Johnson, Lynda Kwon Beaupin, Michael P. Link, Kevin C. Oeffinger, Kathleen M. Orr, Damon Reed, Holly L. Spraker, Deborah A. Thomas, Margaret von Mehren, Daniel S. Wechsler, Kimberly F. Whelan, Brad Zebrack, Dorothy A. Shead, and Hema Sundar

with cancer. 2 The distinct biology of the disease and developmental issues specific to the AYA population (eg, fertility; family planning; pregnancy; education; career development; employment; sexually transmitted diseases; tobacco, alcohol, and