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Scott M. Schuetze

for patients aged under 40 years with bone sarcoma in Britain, 1980–1994 . Br J Cancer 2006 ; 94 : 22 – 29 . 4. Bacci G Mercuri M Longhi A . Neoadjuvant chemotherapy for the treatment of osteosarcoma of the extremities: a comparison of

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Carol D. Morris

these difficult cases as they pertain to the pelvis are highlighted. Osteogenic Sarcoma Osteogenic sarcoma (also called osteosarcoma ) is the most common primary tumor of bone, with approximately 900 cases diagnosed in the United States annually

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Borislav Hristov, Ori Shokek and Deborah A. Frassica

metastatic Ewing's sarcoma . Cancer 2006 ; 106 : 1790 - 1793 . 23. Ozaki T Flege S Kevric M . Osteosarcoma of the pelvis: experience of the Cooperative Osteosarcoma Study Group . J Clin Oncol 2003 ; 21 : 334 – 341 . 24. Gaitan

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Rashmi Chugh

are sarcomas, specifically osteosarcoma, chondrosarcoma, and Ewing's sarcoma (EWS). Survival has improved for osteosarcoma and EWS, with cure rates increasing almost 4-fold (∼ 15%–60%) over the past 30 years, as multidisciplinary management has

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J. Sybil Biermann, Douglas R. Adkins, Mark Agulnik, Robert S. Benjamin, Brian Brigman, James E. Butrynski, David Cheong, Warren Chow, William T. Curry, Deborah A. Frassica, Frank J. Frassica, Kenneth R. Hande, Francis J. Hornicek, Robin L. Jones, Joel Mayerson, Sean V. McGarry, Brian McGrath, Carol D. Morris, Richard J. O'Donnell, R. Lor Randall, Victor M. Santana, Robert L. Satcher, Herrick J. Siegel, Margaret von Mehren, Mary Anne Bergman and Hema Sundar

the United States and 1440 people will die of the disease. 3 Primary bone cancers demonstrate wide clinical heterogeneity and are often curable with proper treatment. Osteosarcoma (35%), chondrosarcoma (30%), and Ewing sarcoma (16%) are the most

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J. Sybil Biermann, Warren Chow, Damon R. Reed, David Lucas, Douglas R. Adkins, Mark Agulnik, Robert S. Benjamin, Brian Brigman, G. Thomas Budd, William T. Curry, Aarati Didwania, Nicola Fabbri, Francis J. Hornicek, Joseph B. Kuechle, Dieter Lindskog, Joel Mayerson, Sean V. McGarry, Lynn Million, Carol D. Morris, Sujana Movva, Richard J. O'Donnell, R. Lor Randall, Peter Rose, Victor M. Santana, Robert L. Satcher, Herbert Schwartz, Herrick J. Siegel, Katherine Thornton, Victor Villalobos, Mary Anne Bergman and Jillian L. Scavone

the disease. 2 Primary bone cancers demonstrate wide clinical heterogeneity and are often curable with proper treatment. Osteosarcoma (35%), chondrosarcoma (30%), and Ewing sarcoma (16%) are the 3 most common forms of bone cancer. Various types of

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Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance

Primary bone cancers are extremely rare neoplasms, accounting for less than 0.2% of all cancers. Primary bone cancers show wide clinical heterogeneity and, perhaps most importantly, are often curable. With current multimodality treatment, including multi-agent chemotherapy, approximately three quarters of all patients diagnosed with osteosarcoma are cured. Updates for 2007 include changes in recommendations for treating chondrosarcoma, Ewing's sarcoma, and osteosarcoma.

For the most recent version of the guidelines, please visit NCCN.org

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Jorge Casas-Ganem and John H. Healey

Marina N Gebhardt M Teot L Gorlick R . Biology and therapeutic advances for pediatric osteosarcoma . Oncologist 2004 ; 9 : 422 – 441 . 4 Marec-Berard P Philip T . Ewing sarcoma: the pediatrician's point of view . Pediatr Blood Cancer

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J. Sybil Biermann, Douglas R. Adkins, Robert S. Benjamin, Brian Brigman, Warren Chow, Ernest U. Conrad III, Deborah A. Frassica, Frank J. Frassica, Suzanne George, Kenneth R. Hande, Francis J. Hornicek, G. Douglas Letson, Joel Mayerson, Sean V. McGarry, Brian McGrath, Carol D. Morris, Richard J. O'Donnell, R. Lor Randall, Victor M. Santana, Robert L. Satcher, Herrick J. Siegel, Neeta Somaiah and Alan W. Yasko

. Osteosarcoma (35%), chondrosarcoma (30%), and Ewing's sarcoma (16%) are the 3 most common forms of bone cancer. Malignant fibrous histiocytoma (MFH) and fibrosarcoma of the bone constitute fewer than 1% of all primary bone tumors. Chondrosarcoma is usually

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Judd E. Cummings, J. Andrew Ellzey and Robert K. Heck

in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols . J Clin Oncol 2002 ; 20 : 776 – 790 . 2. Bacci G Ferrari S Bertoni F . Long