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Jeffrey F. Moley

Patients with established MTC (palpable or present on imaging studies, with elevated calcitonin levels) should undergo total thyroidectomy and central neck dissection, and unilateral or bilateral dissection of levels II through V nodes should be considered

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David M. Brizel, William Lydiatt and A. Dimitrios Colevas

prospectively showed that adjuvant postoperative concurrent chemoradiation is more efficacious than adjuvant radiation alone when extracapsular nodal extension is present. 35 , 36 Adjuvant neck dissection should be performed when residual nodal disease

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Francis P. Worden and Huan Ha

papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial . J Natl Cancer Inst 2008 ; 100 : 261 – 269 . 59. McHam SA Adelstein DJ Rybicki LA . Who merits a neck dissection after definitive chemoradiotherapy for N

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David G. Pfister, Kie-Kian Ang, David M. Brizel, Barbara Burtness, Anthony J. Cmelak, A. Dimitrios Colevas, Frank Dunphy, David W. Eisele, Jill Gilbert, Maura L. Gillison, Robert I. Haddad, Bruce H. Haughey, Wesley L. Hicks Jr., Ying J. Hitchcock, Merrill S. Kies, William M. Lydiatt, Ellie Maghami, Renato Martins, Thomas McCaffrey, Bharat B. Mittal, Harlan A. Pinto, John A. Ridge, Sandeep Samant, Giuseppe Sanguineti, David E. Schuller, Jatin P. Shah, Sharon Spencer, Andrea Trotti III, Randal S. Weber, Gregory Wolf and Frank Worden

surgery combined with radiation are better than those after radiation alone. 30 Treatment of the Neck Neck dissection and postoperative radiation are recommended for clinical nodal disease. 34 , 35 The role of elective neck treatment is unclear

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Michael D. Green and James A. Hayman

used to conformally deliver adjuvant photon RT to a patient with stage IIIB MCC of the left cheek involving the parotid gland (CTV: red) following wide local excision and left neck dissection. Again, bolus (yellow) was used to ensure full dose to the

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Elizabeth G. Grubbs and Douglas B. Evans

. Eur J Surg Oncol 2006 ; 32 : 917 – 921 . 18. Robbins KT Clayman G Levine PA . Neck dissection classification update: revisions proposed by the American Head and Neck Society and the American Academy of Otolaryngology-Head and Neck Surgery

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Shrujal S. Baxi, Lara Dunn and David G. Pfister

cancer. PET/CT after treatment is only specifically mentioned in the context of a decision algorithm for assessing whether to perform a neck dissection or observe the neck after chemoradiation or radiation treatment. 1 Otherwise, the NCCN Guidelines for

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David G. Pfister, Kie-Kian Ang, David M. Brizel, Barbara A. Burtness, Anthony J. Cmelak, A. Dimitrios Colevas, Frank Dunphy, David W. Eisele, Jill Gilbert, Maura L. Gillison, Robert I. Haddad, Bruce H. Haughey, Wesley L. Hicks Jr., Ying J. Hitchcock, Merrill S. Kies, William M. Lydiatt, Ellie Maghami, Renato Martins, Thomas McCaffrey, Bharat B. Mittal, Harlan A. Pinto, John A. Ridge, Sandeep Samant, Giuseppe Sanguineti, David E. Schuller, Jatin P. Shah, Sharon Spencer, Andy Trotti III, Randal S. Weber, Gregory T. Wolf and Frank Worden

of Surgery, pages 620–624. 1 , 39 Resectable disease, neck dissection, postoperative management, and salvage surgery of high-risk disease are discussed in the following sections. Resectable Versus Unresectable Disease The term unresectable

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David G. Pfister, Sharon Spencer, David M. Brizel, Barbara Burtness, Paul M. Busse, Jimmy J. Caudell, Anthony J. Cmelak, A. Dimitrios Colevas, Frank Dunphy, David W. Eisele, Jill Gilbert, Maura L. Gillison, Robert I. Haddad, Bruce H. Haughey, Wesley L. Hicks Jr, Ying J. Hitchcock, Antonio Jimeno, Merrill S. Kies, William M. Lydiatt, Ellie Maghami, Renato Martins, Thomas McCaffrey, Loren K. Mell, Bharat B. Mittal, Harlan A. Pinto, John A. Ridge, Cristina P. Rodriguez, Sandeep Samant, David E. Schuller, Jatin P. Shah, Randal S. Weber, Gregory T. Wolf, Frank Worden, Sue S. Yom, Nicole R. McMillian and Miranda Hughes

surveillance (including posttreatment neck evaluation) are discussed in the algorithm (see “Principles of Surgery” online, in these guidelines, at NCCN.org ). 38 , 39 Resectable disease, neck dissection, postoperative management, and salvage surgery for high

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Chad E. Galer and Merrill S. Kies

or in combination with neck dissection . Int J Radiat Oncol Biol Phys 2001 ; 50 : 55 – 63 . 13. Colletier PJ Garden AS Morrison WH . Postoperative radiation for squamous cell carcinoma metastatic to cervical lymph nodes from an unknown