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Edward C. Li and Jessica DeMartino

practice is a necessary last step in the evidence-based medicine process of caring for patients. The clinical application of these studies could considerably aid the clinical decision-making process, which currently judges and evaluates the available data

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Margaret Tempero

practice guidelines. The diversity part was a bit trickier. Guidelines and quality care beg for evidence-based medicine to guide the process, and health services research to ensure dissemination and assess outcomes. But at the same time, our ability to

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Margaret Tempero

payers and determinants of cost of care. Evidence-based medicine will always remain best practice, but defining best of care for increasingly small subsets based on molecular, not clinical, findings will be a challenge. As for the business of medical

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-of-care access to the NCCN Guidelines and an ability to incorporate patient-specific factors through novel technology that assists clinical decision-making.” “The collaboration between Proventys and NCCN represents the perfect blend of evidence-based medicine

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Michael A. Kolodziej

comparative effectiveness will actually look like, I asked in exasperation, “As a provider, what do you want me to do?” I offer here a modest proposal for what we can and should do. Commitment to Evidence-Based Medicine The rapid rise in the costs

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Laurie Elit, Gregory R. Pond, and Mark N. Levine

Wilkins; 2005 . 7. Laupacis A , Wells , G , Richardson WS , Tugwell P . Users’ guides to the medical literature. V. How to use an article about prognosis. Evidence-Based Medicine Working Group . JAMA 1994 ; 272 : 234 – 237 . 10.1001/jama.1994

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Fikri İçli, Hakan Akbulut, Shouki Bazarbashi, Mehmet Ayhan Kuzu, Mohandas K. Mallath, Kakil Ibrahim Rasul, Scott Strong, Aamir Ali Syed, Faruk Zorlu, and Paul F. Engstrom

colorectal cancer should ideally be based on evidence-based medicine, standardized practices do not exist in other parts of the world. The social, cultural, and economic differences among the countries may be responsible for this lack of standard management

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Harold J. Burstein

. Levels of Evidence: Many commercial pathways developers tout their reliance on evidence-based medicine, and in particular, level 1 evidence. Level 1 usually implies data from randomized trials, often even requiring meta-analyses of multiple randomized

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Frederic W. Grannis Jr

, and research experience in medicine is increasingly considered an impediment rather than a virtue in the search for scientific truth. The methods espoused by the McMaster University evidence-based medicine (EBM) group and, most recently, in the pages

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Margaret Tempero

-cutter approach. Arguably, because of evidence-based medicine, that’s probably the right choice for most patients. But exceptions and outliers always exist. Every day we see patients with certain comorbidities or disease features for whom deviation from a