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Neal J. Meropol, Joanne S. Buzaglo, Jennifer Millard, Nevena Damjanov, Suzanne M. Miller, Caroline Ridgway, Eric A. Ross, John D. Sprandio, and Perry Watts

Although clinical trial research is required for the development of improved treatment strategies, very few cancer patients participate in these studies. The purpose of this study was to describe psychosocial barriers to clinical trial participation among oncologists and their cancer patients. A survey was distributed to all medical oncologists in Pennsylvania and a subset of their patients. Relevant background information and assessment of practical and psychosocial barriers to clinical trial participation were assessed. Among 137 oncologists and 170 patients who completed the surveys, 84% of patients were aware of clinical trials, and oncologists and patients generally agreed that clinical trials are important to improving cancer treatment. However, oncologists and patients were more likely to consider clinical trials in advanced or refractory disease. When considering 7 potential barriers to clinical trials, random assignment and fear of receiving a placebo were ranked highly by both patients and oncologists. Patients identified fear of side effects as the greatest barrier to clinical trial participation, whereas oncologists ranked this psychosocial barrier as least important to their patients. Overall, the study found that although oncologists and patients are aware of clinical trials and have favorable attitudes toward them, psychosocial barriers exist for patients that may impact participation in clinical trials. Furthermore, important discrepancies exist between the perceptions of oncologists and those of patients regarding what the psychosocial barriers are. We concluded that characterizing oncologist and patient perceived barriers can help improve communication and decision making about clinical trials, such that participation may be optimized.

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Narek Shaverdian, Erin F. Gillespie, Elaine Cha, Soo Young Kim, Stephanie Benvengo, Fumiko Chino, Jung Julie Kang, Yuelin Li, Thomas M. Atkinson, Nancy Lee, Charles M. Washington, Oren Cahlon, and Daniel R. Gomez

telemedicine in a rural clinic . Am J Public Health 1994 ; 84 : 1693 . 10.2105/AJPH.84.10.1693 11. Ong LML , Visser MRM , Lammes FB , Doctor-patient communication and cancer patients’ quality of life and satisfaction . Patient Educ

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Kristine A. Donovan, George Handzo, Cheyenne Corbett, Jessica Vanderlan, Benjamin W. Brewer, and Kauser Ahmed

. Psychooncology 2012 ; 21 : 1346 – 1356 . 21905157 10.1002/pon.2045 7. Ha JF , Longnecker N . Doctor-patient communication: a review . Ochsner J 2010 ; 10 : 38 – 43 . 21603354 8. Carrera PM , Kantarjian HM , Blinder VS . The

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Romy M. van Amelsfoort, Iris Walraven, Jacobien Kieffer, Edwin P.M. Jansen, Annemieke Cats, Nicole C.T. van Grieken, Elma Meershoek-Klein Kranenbarg, Hein Putter, Johanna W. van Sandick, Karolina Sikorska, Cornelis J.H. van de Velde, Neil K. Aaronson, Marcel Verheij, and on behalf of the CRITICS Investigators

predicted survival. These findings provide consistent evidence supporting the potential usefulness of taking baseline HRQoL into account in doctor–patient communication and in shared decision-making about the choice of treatment. We are the first to apply

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Tara M. Mackay, Lennart B. van Rijssen, Jurr O. Andriessen, Mustafa Suker, Geert-Jan Creemers, Ferry A. Eskens, Ignace H. de Hingh, Lonneke V. van de Poll-Franse, Mirjam A.G. Sprangers, Olivier R. Busch, Johanna W. Wilmink, Casper H. van Eijck, Marc G. Besselink, Hanneke W. van Laarhoven, and on behalf of the Dutch Pancreatic Cancer Group

, Visser MR , Lammes FB , . Doctor–patient communication and cancer patients’ quality of life and satisfaction . Patient Educ Couns 2000 ; 41 : 145 – 156 . 10.1016/S0738-3991(99)00108-1 12024540 30. Vashisht A , Domoney CL , Handscomb K