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Andrew D. Boyd and Michelle Riba

1968 ; 55 : 191 – 198 . 3. Yaskin JC . Nervous symptoms as earliest manifestations of carcinoma of the pancreas . JAMA 1931 ; 96 : 1664 – 1668 . 4. Shakin E Holland J . Depression and pancreatic cancer . J Pain Symptom Manage

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Sylvie D. Lambert, Kerrie Clover, Julie F. Pallant, Benjamin Britton, Madeleine T. King, Alex J. Mitchell and Gregory Carter

Background Approximately 15% of patients with cancer report clinically significant depression, with prevalence rates ranging from 0% to 58% 1 – 6 —this makes depression one of the most common psychological symptoms for this patient population

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Alex J. Mitchell

distress, which had previously received little attention compared with depression. 1 Distress is a very common complication of cancer at any stage and often occurs when multiple needs are unmet. 2 , 3 The presence of distress is also linked with reduced

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Monira Alwhaibi, Usha Sambamoorthi, Suresh Madhavan, Thomas Bias, Kimberly Kelly and James Walkup

Background Depression is a highly prevalent mental health condition among elderly cancer survivors (age >65 years). According to the CDC, “cancer survivor refers to a person who has been diagnosed with cancer, from the time of diagnosis

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Archna Sarwal and Andrew J. Roth

& Febiger , 1982 : 1175 – 1203 . 3 Wells KB Rogers W Burnham MA . Course of depression in patients with hypertension, myocardial infarction, or insulin-dependent diabetes . Am J Psychiatry 1993 ; 150 : 632 – 638 . 4 Passik

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Jimmie C. Holland, Barbara Andersen, William S. Breitbart, Bruce Compas, Moreen M. Dudley, Stewart Fleishman, Caryl D. Fulcher, Donna B. Greenberg, Carl B. Greiner, George F. Handzo, Laura Hoofring, Paul B. Jacobsen, Sara J. Knight, Kate Learson, Michael H. Levy, Matthew J. Loscalzo, Sharon Manne, Randi McAllister-Black, Michelle B. Riba, Kristin Roper, Alan D. Valentine, Lynne I. Wagner and Michael A. Zevon

, pain, anxiety, and depression are the most frequently reported cancer-related symptoms that interfere with the patient's ability to perform daily activities. 13 The prevalence of psychological distress in individuals varies by cancer type. In a study

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Claudia S.E.W. Schuurhuizen, Annemarie M.J. Braamse, Aartjan T.F. Beekman, Pim Cuijpers, Mecheline H.M. van der Linden, Adriaan W. Hoogendoorn, Hans Berkhof, Dirkje W. Sommeijer, Vera Lustig, Suzan Vrijaldenhoven, Haiko J. Bloemendal, Cees J. van Groeningen, Annette A. van Zweeden, Maurice J.D.L. van der Vorst, Ron Rietbroek, Cathrien S. Tromp-van Driel, Machteld N.W. Wymenga, Peter W. van der Linden, Aart Beeker, Marco B. Polee, Erdogan Batman, Maartje Los, Aart van Bochove, Jan A.C. Brakenhoff, Inge R.H.M. Konings, Henk M.W. Verheul and Joost Dekker

and 18 weeks thereafter. Screening was performed using the Hospital Anxiety and Depression Scale (HADS) 15 and Distress Thermometer/Problem List (DT/PL). 16 , 17 Scores of ≥13 on the HADS 15 or ≥5 on the DT 16 were seen as indicators of elevated

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Siew Tzuh Tang, Jen-Shi Chen, Fur-Hsing Wen, Wen-Chi Chou, John Wen-Cheng Chang, Chia-Hsun Hsieh and Chen Hsiu Chen

, 16 but also does not detrimentally affect patients’ anxiety, depression, and QoL. 14 , 18 , 19 However, the robustness and validity of these ACP RCT findings are threatened by several methodological insufficiencies. 3 , 20 First, all but one 13 of

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Chunkit Fung, Paul C. Dinh Jr, Sophie D. Fossa and Lois B. Travis

-related complications, including second malignant neoplasms (SMNs), cardiovascular disease (CVD), ototoxicity, neurotoxicity, nephrotoxicity, pulmonary toxicity, hypogonadism, infertility, anxiety, depression, cognitive impairment, and chronic cancer-related fatigue

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Daniel C. McFarland, Heather Polizzi, John Mascarenhas, Marina Kremyanskaya, Jimmie Holland and Ronald Hoffman

that is frequently encountered in patients with MPNs over the course of many years. In many malignancies and advanced cancers, symptom burden tends to correlate with the prevalence of distress, anxiety, and depression. 1 , 2 In fact, the severity of