clinical stage II/III rectal cancer (T3/4N1-2 based on endorectal ultrasound or MRI) who had been treated with initial chemotherapy followed by chemoradiation at MSKCC between 2007 and 2012. Patients were chosen based on the treating physician’s comfort
Search Results
Neoadjuvant Chemotherapy First, Followed by Chemoradiation and Then Surgery, in the Management of Locally Advanced Rectal Cancer
Andrea Cercek, Karyn A. Goodman, Carla Hajj, Emily Weisberger, Neil H. Segal, Diane L. Reidy-Lagunes, Zsofia K. Stadler, Abraham J. Wu, Martin R. Weiser, Philip B. Paty, Jose G. Guillem, Garrett M. Nash, Larissa K. Temple, Julio Garcia-Aguilar, and Leonard B. Saltz
Short-Course Radiation Versus Long-Course Chemoradiation for Rectal Cancer
Bruce D. Minsky, Claus Rödel, and Vincenzo Valentini
The 2 broad approaches to preoperative therapy for rectal cancer are chemoradiation and short-course radiation. The evolution to preoperative therapy is based on data from 2 randomized trials in which patients received preoperative therapy
Evolving Treatment Options for Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma
Pelin Cinar and Andrew H. Ko
treatment options for patients with locally advanced unresectable PDAC Explain the roles of systemic therapy and chemoradiation for locally advanced PDAC including optimal sequencing, recent improvements in chemotherapy, and whether radiotherapy improves
Chemoradiation Improves Survival Compared With Chemotherapy Alone in Unresected Nonmetastatic Gastric Cancer
Richard Li, Wei-Hsien Hou, Joseph Chao, Yanghee Woo, Scott Glaser, Arya Amini, Rebecca A. Nelson, and Yi-Jen Chen
dissection, has been established as the primary curative treatment modality for locally advanced gastric cancer. 3 , 4 Perioperative chemotherapy, adjuvant chemotherapy, or adjuvant chemoradiation (CRT) are given in conjunction with surgery based on data
Disparate Use of Chemoradiation in Elderly Patients With Localized Anal Cancer
Eric D. Miller, Ansel P. Nalin, Dayssy A. Diaz Pardo, Andrea L. Arnett, Emily Huang, Alessandra C. Gasior, Pannaga Malalur, Hui-Zi Chen, Terence M. Williams, and Jose G. Bazan
increase in mortality has been observed, with a nearly 5% increase in SCCA-based mortality in patients aged 60 to 69 years. 2 The current standard of care (SOC) for treatment of localized SCCA is definitive chemoradiation (CRT) with concurrent multiagent
Controversies in the Locoregional Management of Head and Neck Cancer
David M. Brizel, William Lydiatt, and A. Dimitrios Colevas
, elimination of cisplatin-based concurrent systemic therapy, use of alternative systemic agents such as cetuximab, or an increased reliance on primary surgical therapy instead of (chemo)radiation have all been proposed. The crux of the debate is whether
Relationship Between Hemoglobin Levels and Quality of Life During Radiation Therapy Plus Concomitant or Sequential Chemotherapy in Patients With Cancer and Anemia Treated With Epoetin Alfa
Daniel Shasha, Pierre Cremieux, and Louis Harrison
chemoradiation for resectable rectal cancer . Cancer 2001 ; 92 ( suppl 6 ): 1725 – 1732 . 9 Sobrero A Puglisi F Guglielmi A . Fatigue: A main component of anemia symptomatology . Semin Oncol 2001 ; 28 ( suppl 8 ): 15 – 18 . 10 Vigario
Acute and Chronic Complications After Treatment of Locoregional Anal Cancer: Prevention and Management Strategies
Leah Katz, David P. Horowitz, and Lisa A. Kachnic
-Montefiore D , Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I) . Br J Cancer 2010 ; 102 : 1123 – 1128 . 9. UKCCCR Anal Cancer Trial Working Party . Epidermoid anal
Post-Chemoradiation Surgical Pathology Stage Can Customize the Surveillance Strategy in Patients With Esophageal Adenocarcinoma
Takashi Taketa, Kazuki Sudo, Arlene M. Correa, Roopma Wadhwa, Hironori Shiozaki, Elena Elimova, Maria-Claudia Campagna, Mariela A. Blum, Heath D. Skinner, Ritsuko U. Komaki, Jeffrey H. Lee, Manoop S. Bhutani, Brian R. Weston, David C. Rice, Stephen G. Swisher, Dipen M. Maru, Wayne L. Hofstetter, and Jaffer A. Ajani
surgery, the most common recommendation is chemoradiation followed by surgery, or trimodality therapy (TMT). 5 , 6 Despite advances in the treatment of localized EAC, the cure rate remains at 30% to 45% for patients with clinical stage II or III, and
Comparison of Pathologic Stage in Patients Receiving Esophagectomy With and Without Preoperative Chemoradiation Therapy for Esophageal SCC
Bing-Yen Wang, Ping-Yi Lin, Shiao-Chi Wu, Hui-Shan Chen, Po-Kuei Hsu, Chih-Shiun Shih, Chao-Yu Liu, Chia-Chuan Liu, and Yao-Li Chen
Clinical Practice Guidelines for Oncology (NCCN Guidelines) for Esophageal and Esophagogastric Junction Cancers, treatment options for patients with locoregional cancer (T1b,N+, T2–T4a,N0–N+) include esophagectomy with or without preoperative chemoradiation
