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Amy Ly, Jill C. Ono, Kevin S. Hughes, Martha B. Pitman and Ronald Balassanian

Background The American Cancer Society estimated that 232,670 new cases of female breast cancer would occur in 2014, with more than 1 million women undergoing breast biopsy. 1 , 2 The prediagnosis period in particular is a time of acute

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Patricia Ellen Goldhoff, Poonam Vohra, Kanti Pallav Kolli and Britt-Marie Ljung

Background Image-guided percutaneous biopsy is one of the most common procedures performed in radiology departments, 1 and the volume of these procedures is increasing. 2 At the same time, rapid advances in both molecular diagnostic testing of

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Badar M. Mian

. CA Cancer J Clin 2003 ; 53 : 5 – 26 . 2 Hodge KK McNeal JE Terris MK .: Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate . J Urol 1989 ; 142 : 71 – 74 . 3 Stamey TA . Making the

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Hiram S. Cody III and Kimberly J. Van Zee

1994 ; 220 : 391 – 401 . 3 Cody HS . Clinical aspects of sentinel node biopsy . Breast Cancer Res 2001 ; 3 : 104 – 108 . 4 Giuliano AE Dale PS Turner RR . Improved staging of breast cancer with sentinel lymphadenectomy . Ann

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Robert H. I. Andtbacka and Jeffrey E. Gershenwald

patients: validation of the American Joint Committee on Cancer melanoma staging system . J Clin Oncol 2001 ; 19 : 3622 – 3634 . 5 Thompson JF Shaw HM . Is sentinel lymph node biopsy appropriate in patients with thin melanomas: too early to

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Stephen B. Edge and David G. Sheldon

The authors have no financial interests, arrangement, or affiliations with the manufacturers of any products discussed in the article or with their competitors. References 1 Pendas S Dauway E Giuliano R . Sentinel node biopsy in

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Kevin S. Scher, Juan-Sebastian Saldivar, Michael Fishbein, Alberto Marchevsky and Karen L. Reckamp

found to have enlarged right hilar, paratracheal, subcarinal, and subcentimeter supraclavicular lymph nodes. CT-guided biopsy results of the lung mass indicated moderately differentiated adenocarcinoma ( Table 1 ). PET scan showed increased

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Daniel G. Coit and Anthony J. Olszanski

outcomes. Diagnosis, Workup, and Initial Management For the initial diagnosis of melanoma, an excisional biopsy with 1- to 3-mm margins is preferred, but shave biopsy is acceptable, especially when the index of suspicion of malignancy is low. However

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Edward E. Partridge, Nadeem R. Abu-Rustum, Susan M. Campos, Patrick J. Fahey, Michael Farmer, Rochelle L. Garcia, Anna Giuliano, Howard W. Jones III, Subodh M. Lele, Richard W. Lieberman, Stewart L. Massad, Mark A. Morgan, R. Kevin Reynolds, Helen E. Rhodes, Diljeet K. Singh, Karen Smith-McCune, Nelson Teng, Cornelia Liu Trimble, Fidel Valea and Sharon Wilczynski

Testing on page 1378 for more detail about these tests.) Colposcopy, along with colposcopically directed biopsies, is the primary method for evaluating women with abnormal cervical cytologies. During a colposcopic examination, the cervix is viewed

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Paul F. Engstrom, Juan Pablo Arnoletti, Al B. Benson III, Jordan D. Berlin, J. Michael Berry, Yi-Jen Chen, Michael A. Choti, Harry S. Cooper, Raza A. Dilawari, Dayna S. Early, Peter C. Enzinger, Marwan G. Fakih, James Fleshman Jr., Charles Fuchs, Jean L. Grem, James A. Knol, Lucille A. Leong, Edward Lin, Mary F. Mulcahy, Eric Rohren, David P. Ryan, Leonard Saltz, David Shibata, John M. Skibber, William Small Jr., Constantinos Sofocleous, James Thomas, Alan P. Venook and Christopher Willett

not involve a surgical excision, most tumors are staged clinically, with an emphasis on the primary tumor size determined through direct examination and microscopic confirmation. 14 An incisional tumor biopsy is required. Rectal ultrasound to