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David C. Dale

References 1 Dale DC . Nonmalignant disorders of leukocytes . In: Dale DC Federman DD , eds. ACP Medicine 2006. New York : WebMD, Inc. ; 2006 : 1030 – 1037 . 2 Dale DC Boxer LA Liles WC . The phagocytes: neutrophils

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Marina Stasenko, R. Kevin Reynolds, Carolyn Johnston, Melissa Brackman, Karen McLean, and Shitanshu Uppal

-0262 used hematologic hold parameters that were lower than the conventional regimen hold parameters. Chemotherapy day 1 absolute neutrophil count (ANC) hold parameters were decreased to 1.0 × 10 9 cells/L from conventional levels of 1.5 × 10 9 cells

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Arjan A. van de Loosdrecht and Theresia M. Westers

45 expression on myeloid progenitor cells compared with that of reference lymphocytes (≤4.0 or ≥7.5) A decreased sideward light scatter (SSC) of neutrophils compared with that of reference lymphocytes (≤6.0) Displayed reference ranges were

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Gary H. Lyman and David C. Dale

have blood neutrophil counts that are chronically or intermittently less than 0.5 × 10 9 /L for several years or their lifetime. SCN can be inherited or acquired and is usually categorized as cyclic, congenital, or idiopathic based on clinical and

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Rafael Bejar

-risk disease ( Figure 1 ). Figure 1. Revised IPSS-R. Abbreviations: ANC, absolute neutrophil count; AML, acute myeloid leukemia; IPSS-R, Revised International Prognostic Scoring System. Adapted from Schanz J, Tüchler H, Solé F, et al. New comprehensive

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Michelle T. Ashworth and Adil Daud

with mild residual nodularity, and no new lesions; MRI of the brain was also negative for new or progressive disease. A decreased absolute neutrophil/lymphocyte ratio was observed in correlation with response to treatment with ipilimumab ( Figure 2

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Nirmala K. Manjappachar, John A. Cuenca, Claudia M. Ramírez, Mike Hernandez, Peyton Martin, Maria P. Reyes, Alba J. Heatter, Cristina Gutierrez, Nisha Rathi, Charles L. Sprung, Kristen J. Price, and Joseph L. Nates

of septic shock diagnosis, maximum SOFA score during the ICU stay, length of stay (pre-ICU, ICU, hospital), neutropenia (absolute neutrophil count [ANC] ≤1,500/mm 3 ), severe neutropenia (ANC <500/mm 3 ), therapeutic interventions during the ICU stay

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Kavea Panneerselvam, Rajan N. Amin, Dongguang Wei, Dongfeng Tan, Phillip J. Lum, Hao Chi Zhang, David M. Richards, Mehmet Altan, Petros Grivas, John A. Thompson, Anusha S. Thomas, and Yinghong Wang

magnification ×20) of esophageal mucosa showing chronic active esophagitis, with increased numbers of neutrophils in the squamous epithelium and lamina propria. Granulation tissue, clusters of lymphocytes, and plasma cells are shown in the lamina propria (arrows

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Jeffrey Crawford, James Armitage, Lodovico Balducci, Charles Bennett, Douglas W. Blayney, Spero R. Cataland, David C. Dale, George D. Demetri, Harry P. Erba, James Foran, Alison G. Freifeld, Marti Goemann, Mark L. Heaney, Sally Htoy, Susan Hudock, Dwight D. Kloth, David J. Kuter, Gary H. Lyman, Laura Boehnke Michaud, Sarah C. Miyata, Martin S. Tallman, Saroj Vadhan-Raj, Peter Westervelt, and Michael K. Wong

Park) 2003 ; 17 : 8 – 13 . 37 Azoulay E Attalah H Harf A . Granulocyte colony-stimulating factor or neutrophil-induced pulmonary toxicity: myth or reality? Systematic review of clinical case reports and experimental data . Chest 2001

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Pamala A. Pawloski, Cara L. McDermott, James H. Marshall, Vanita Pindolia, Catherine M. Lockhart, Catherine A. Panozzo, Jeffrey S. Brown, and Bernadette Eichelberger

subsequent meta-analysis of clinical trials demonstrated no significant differences in the mean duration of severe neutropenia, absolute neutrophil count (ANC) nadir depth or time to ANC recovery, FN incidence, or safety. 29 Data regarding G-CSF biosimilar