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Principles of Surgical Management of Peritoneal Mesothelioma

Jessica A. Steadman and Travis E. Grotz

, 2 Radical resection with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) remains the primary curative therapy for malignant peritoneal mesothelioma (MPeM), and the strongest predictor of long-term survival is

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HSR19-110: Predicting Candidates for Cytoreductive Surgery and HIPEC: The Role of Computed Tomography and Diagnostic Laparoscopy

Leigh Selesner, Gabrielle Gauvin, Dorotea Mutabdzic, Eileen O’Halloran, Maxwell Kilcoyne, Kwan-Keat Ang, Jeffrey Farma, Elin Sigurdson, and Sanjay Reddy

Introduction: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CS/HIPEC) has led to improved survival in select patients with peritoneal surface malignancies. Predicting the volume of disease and any unresectable disease is

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CLO23-050: Total Neoadjuvant Chemotherapy Followed by HIPEC and Curative Surgery in Treatment of Locally Advanced Gastric Cancer

Veronika Patsko, Oleksii Dobrzhankiy, and Yurii Kondratsky

Objectives: HIPEC shows promising results in treatment of patients with ovarian and colorectal cancer. It showed significant improvement of overall survival (OS) and progression free survival (PFS) in selected patients. We aimed to research

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Healthcare Access Dimensions and Guideline-Concordant Ovarian Cancer Treatment: SEER-Medicare Analysis of the ORCHiD Study

Mary Katherine Montes de Oca, Lauren E. Wilson, Rebecca A. Previs, Anjali Gupta, Ashwini Joshi, Bin Huang, Maria Pisu, Margaret Liang, Kevin C. Ward, Maria J. Schymura, Andrew Berchuck, and Tomi F. Akinyemiju

Guidelines) for Ovarian Cancer, Version 2.2013. This diagram does not reflect the full NCCN recommendations and is limited to clinical information and treatments that can be assessed in the SEER-Medicare database. Abbreviations: HIPEC, hyperthermic

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Current Concepts in the Evaluation and Treatment of Patients With Diffuse Malignant Peritoneal Mesothelioma

Keli Turner, Sheelu Varghese, and H. Richard Alexander

intraperitoneal chemotherapy (HIPEC), usually with mitomycin C or cisplatin, has been largely established as the best initial therapeutic intervention in selected patients with DMPM. The intent of operation with CRS and HIPEC is to remove all gross disease and

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NCCN Guidelines Insights: Ovarian Cancer, Version 1.2019

Featured Updates to the NCCN Guidelines

Deborah K. Armstrong, Ronald D. Alvarez, Jamie N. Bakkum-Gamez, Lisa Barroilhet, Kian Behbakht, Andrew Berchuck, Jonathan S. Berek, Lee-may Chen, Mihaela Cristea, Marie DeRosa, Adam C. ElNaggar, David M. Gershenson, Heidi J. Gray, Ardeshir Hakam, Angela Jain, Carolyn Johnston, Charles A. Leath III, Joyce Liu, Haider Mahdi, Daniela Matei, Michael McHale, Karen McLean, David M. O’Malley, Richard T. Penson, Sanja Percac-Lima, Elena Ratner, Steven W. Remmenga, Paul Sabbatini, Theresa L. Werner, Emese Zsiros, Jennifer L. Burns, and Anita M. Engh

disease is unable to be optimally debulked using minimally invasive techniques should be converted to an open procedure ( supplemental eTable 4 ). Hyperthermic Intraperitoneal Chemotherapy at the Time of IDS Hyperthermic intraperitoneal chemotherapy (HIPEC

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Have We Been Down This Road Before?

Harold J. Burstein

of chemotherapy, warmed to supraphysiologic temperatures so as to more effectively kill residual cancer cells. This simmering chemotherapy is called HIPEC . The procedure is sufficiently controversial as to have generated debate at the ASCO meeting

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CLO23-047: Ivosidenib as a Novel Treatment for Patients With Isocitrate Dehydrogenase-1 Positive Advanced Colon Cancer

Krishna Desai, Kristal Pereira, Akhil Jain, Sabah Iqbal, and Rajesh Thirumaran

a large mass in the ascending colon. Biopsy was diagnostic for metastatic-moderately differentiated mucinous adenocarcinoma. He underwent total colectomy, end ileostomy, & hyperthermic intraperitoneal chemotherapy (HIPEC). FOLFOX (folinic acid

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Mesothelioma: Peritoneal, Version 2.2023, NCCN Clinical Practice Guidelines in Oncology

David S. Ettinger, Douglas E. Wood, James Stevenson, Dara L. Aisner, Wallace Akerley, Jessica R. Bauman, Ankit Bharat, Debora S. Bruno, Joe Y. Chang, Lucian R. Chirieac, Malcolm DeCamp, Thomas J. Dilling, Jonathan Dowell, Gregory A. Durm, Scott Gettinger, Travis E. Grotz, Matthew A. Gubens, Aparna Hegde, Rudy P. Lackner, Michael Lanuti, Jules Lin, Billy W. Loo Jr, Christine M. Lovly, Fabien Maldonado, Erminia Massarelli, Daniel Morgensztern, Trey C. Mullikin, Thomas Ng, Gregory A. Otterson, Sandip P. Patel, Tejas Patil, Patricio M. Polanco, Gregory J. Riely, Jonathan Riess, Theresa A. Shapiro, Aditi P. Singh, Alda Tam, Tawee Tanvetyanon, Jane Yanagawa, Stephen C. Yang, Edwin Yau, Kristina M. Gregory, and Miranda Hughes

disease recurs following CRS with or without hyperthermic intraperitoneal chemotherapy (HIPEC). Similar to pleural mesothelioma, the histologic subtypes of PeM include epithelioid (most common), sarcomatoid, and biphasic (also known as mixed, containing

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Metastatic Colon Cancer, Version 3.2013

Featured Updates to the NCCN Guidelines

Al B. Benson III, Tanios Bekaii-Saab, Emily Chan, Yi-Jen Chen, Michael A. Choti, Harry S. Cooper, Paul F. Engstrom, Peter C. Enzinger, Marwan G. Fakih, Moon J. Fenton, Charles S. Fuchs, Jean L. Grem, Steven Hunt, Ahmed Kamel, Lucille A. Leong, Edward Lin, Kilian Salerno May, Mary F. Mulcahy, Kate Murphy, Eric Rohren, David P. Ryan, Leonard Saltz, Sunil Sharma, David Shibata, John M. Skibber, William Small Jr, Constantinos T. Sofocleous, Alan P. Venook, Christopher G. Willett, Kristina M. Gregory, and Deborah A. Freedman-Cass

cytoreductive surgery (ie, peritoneal stripping surgery) and perioperative hyperthermic intraperitoneal chemotherapy (HIPEC) for the treatment of peritoneal carcinomatosis without extraabdominal metastases. Several surgical series have addressed the role of this