Gastric Cancer Clinical Practice Guidelines in Oncology NCCN Categories of Evidence and Consensus Category 1: The recommendation is based on high-level evidence (e.g., randomized controlled trials) and there is uniform NCCN consensus
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Jaffer A. Ajani, James S. Barthel, Tanios Bekaii-Saab, David J. Bentrem, Thomas A. D'Amico, Prajnan Das, Crystal Denlinger, Charles S. Fuchs, Hans Gerdes, James A. Hayman, Lisa Hazard, Wayne L. Hofstetter, David H. Ilson, Rajesh N. Keswani, Lawrence R. Kleinberg, Michael Korn, Kenneth Meredith, Mary F. Mulcahy, Mark B. Orringer, Raymond U. Osarogiagbon, James A. Posey, Aaron R. Sasson, Walter J. Scott, Stephen Shibata, Vivian E. M. Strong, Mary Kay Washington, Christopher Willett, Douglas E. Wood, Cameron D. Wright, and Gary Yang
Prajnan Das, Yixing Jiang, Jeffrey H. Lee, Manoop S. Bhutani, William A. Ross, Paul F. Mansfield, and Jaffer A. Ajani
T he incidence and mortality of gastric cancer in the United States in 2009 was estimated to be 21,100 and 10,600, respectively. 1 The overall incidence of gastric cancer has decreased during the past several decades, although the incidence of
Matthew D. Callister and Leonard L. Gunderson
/print certificate. Learning Objectives Upon completion of this activity, participants will be able to: • Review locoregional recurrence rates for gastric cancer after surgery alone • List the limitations of radiation therapy for gastric cancer
Jaffer A. Ajani, Thomas A. D'Amico, Khaldoun Almhanna, David J. Bentrem, Joseph Chao, Prajnan Das, Crystal S. Denlinger, Paul Fanta, Farhood Farjah, Charles S. Fuchs, Hans Gerdes, Michael Gibson, Robert E. Glasgow, James A. Hayman, Steven Hochwald, Wayne L. Hofstetter, David H. Ilson, Dawn Jaroszewski, Kimberly L. Johung, Rajesh N. Keswani, Lawrence R. Kleinberg, W. Michael Korn, Stephen Leong, Catherine Linn, A. Craig Lockhart, Quan P. Ly, Mary F. Mulcahy, Mark B. Orringer, Kyle A. Perry, George A. Poultsides, Walter J. Scott, Vivian E. Strong, Mary Kay Washington, Benny Weksler, Christopher G. Willett, Cameron D. Wright, Debra Zelman, Nicole McMillian, and Hema Sundar
States. 1 The proximal lesser curvature, cardia, and the EGJ are the most common sites of gastric cancer in Western countries. 1 Changes in histology and location of upper GI tract tumors have also been observed in some parts of Europe. 2 , 3 It is
Manish A. Shah and David P. Kelsen
, Eastern Europe, and Central America. Gastric cancer is the second most common cause of cancer-related deaths worldwide, with 700,349 deaths annually, 2 and is the third most common malignancy worldwide, with 974,000 new cases in 2000. Gastric cancers are
Quan P. Ly and Aaron R. Sasson
Cancer J Clin . 2008 ; 58 : 71 – 96 . 2. Wilkinson NW Howe J Gay G . Differences in the pattern of presentation and treatment of proximal and distal gastric cancer: results of the 2001 gastric patient care evaluation . Ann Surg Oncol 2008
Jaffer A. Ajani, David J. Bentrem, Stephen Besh, Thomas A. D’Amico, Prajnan Das, Crystal Denlinger, Marwan G. Fakih, Charles S. Fuchs, Hans Gerdes, Robert E. Glasgow, James A. Hayman, Wayne L. Hofstetter, David H. Ilson, Rajesh N. Keswani, Lawrence R. Kleinberg, W. Michael Korn, A. Craig Lockhart, Kenneth Meredith, Mary F. Mulcahy, Mark B. Orringer, James A. Posey, Aaron R. Sasson, Walter J. Scott, Vivian E. Strong, Thomas K. Varghese Jr, Graham Warren, Mary Kay Washington, Christopher Willett, Cameron D. Wright, Nicole R. McMillian, and Hema Sundar
: Describe the postoperative treatment options for patients with resectable gastric cancer. Discuss the role of HER-2 testing and trastuzumab for patients with metastatic cancer. NCCN Guidelines Insights : Gastric Cancer, Version 2.2013 Version 2
David J. Worhunsky, Yifei Ma, Yulia Zak, George A. Poultsides, Jeffrey A. Norton, Kim F. Rhoads, and Brendan C. Visser
Although multiple quality indicators have been studied for the management of gastric cancer, notably surgical technique and the extent of lymph node dissection, 12 – 14 limited data exist regarding implementation and effectiveness of clinical guidelines
Elena Elimova, Roopma Wadhwa, Hironori Shiozaki, Kazuki Sudo, Jeannelyn S. Estrella, Brian D. Badgwell, Prajnan Das, Aurelio Matamoros Jr, Shumei Song, and Jaffer A. Ajani
Gastric cancer (GC) represents a serious health problem on a global scale. It is the second leading cause of cancer-related death worldwide. 1 In the United States, GC is relatively less frequent, with 22,220 new cases and 13,730 cancer deaths
Kohei Shitara and Atsushi Ohtsu
Systemic chemotherapy is a standard treatment for metastatic or unresectable advanced or recurrent gastric cancer (AGC). Effective cytotoxic agents for AGC include 5-fluorouracil (5-FU), oral fluoropyrimidine, platinum agents, taxanes, irinotecan
