trials of ESAs among patients with cancer Distinguish the benefits of ESAs among patients with cancer Evaluate when to use ESAs among patients with cancer Anemia is frequently encountered in patients with cancer and is often multifactorial, with
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Young D. Chang, Jae-Woo Jung, Ritika Oberoi-Jassal, Jongphil Kim, Sahana Rajasekhara, Meghan Haas, Joshua Smith, Vijay Desai, Kristine A. Donovan, and Diane Portman
Assessment Scale (ESAS) has well-established reliability and validity when used in patients with cancer as a routine self-assessment tool. 22 Patients use the ESAS to score their average symptom severity during the 24 hours before presenting for an
Jennifer M. Hinkel, Edward C. Li, and Stephen L. Sherman
(ESAs), blood transfusions, and iron supplementation to maintain hemoglobin levels in patients with cancer. Each of these interventions has complexities and, in some cases, controversies. Moreover, anemia and the interventions used to counter it can have
Camilla Zimmermann, Ashley Pope, Breffni Hannon, Monika K. Krzyzanowska, Gary Rodin, Madeline Li, Doris Howell, Jennifer J. Knox, Natasha B. Leighl, Srikala Sridhar, Amit M. Oza, Rebecca Prince, Stephanie Lheureux, Aaron R. Hansen, Anne Rydall, Brittany Chow, Leonie Herx, Christopher M. Booth, Deborah Dudgeon, Neesha Dhani, Geoffrey Liu, Philippe L. Bedard, Jean Mathews, Nadia Swami, and Lisa W. Le
Edmonton Symptom Assessment System-revised (ESAS-r) 32 on computers or tablets in clinic waiting areas before appointments. 33 Scores are available for review and potential intervention by oncologists and oncology nurses. Participants were recruited
George M. Rodgers
Cancer- and Chemotherapy-Induced Anemia during its early years and have chaired it since 2004. Major changes in the NCCN Guidelines on anemia over the years have focused on 2 topics: erythropoiesis-stimulating agent (ESA) safety and the increasing use of
Linda Watson, Siwei Qi, Claire Link, Andrea DeIure, Arfan Afzal, and Lisa Barbera
Assessment System–Revised (ESAS-r) 14 and the Canadian Problem Checklist (CPC). 15 These measures align with national reporting requirements and provide a comprehensive overview of common symptoms and concerns that patients with cancer experience. 16 The
Anat Gafter-Gvili, David P. Steensma, and Michael Auerbach
More than a decade has passed since Auerbach et al 1 presented the first study demonstrating synergy of intravenous (IV) iron with erythropoiesis-stimulating agents (ESAs) for correcting anemia in patients receiving chemotherapy for malignant
Jeffrey Crawford and George M. Rodgers
Iron for Cancer-Related Anemia Dr. Rodgers discussed the use of IV iron to optimize erythropoietic growth factor therapy or to minimize the need for it. Cancer-related anemia can be treated with erythropoiesis-stimulating agents (ESAs), red blood cell
George M. Rodgers III, Pamela Sue Becker, Morey Blinder, David Cella, Asher Chanan-Khan, Charles Cleeland, Peter F. Coccia, Benjamin Djulbegovic, Jeffrey A. Gilreath, Eric H. Kraut, Ursula A. Matulonis, Michael M. Millenson, Denise Reinke, Joseph Rosenthal, Rowena N. Schwartz, Gerald Soff, Richard S. Stein, Gordana Vlahovic, and Alva B. Weir III
-stimulating agents (ESAs), with or without iron supplementation. Recent studies showing detrimental health effects of ESAs sparked a series of FDA label revisions and a sea change in the perception of these once commonly used agents. In light of this, these
Linda Watson, Siwei Qi, Andrea DeIure, Eclair Photitai, Lindsi Chmielewski, and Louise Smith
Assessment System (ESAS-r) 8 , 9 and the Canadian Problem Checklist (CPC), 10 selected in alignment with the national reporting criteria established by the Canadian Partnership Against Cancer (CPAC). 11 In the process of integrating these patient
