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Karam Khaddour, Michael R. Chicoine, Jiayi Huang, Sonika Dahiya, and George Ansstas

, the BRAF V600E mutation has also been identified in primary intracranial tumors, albeit with an overall lower frequency, with the highest incidence reported in ganglioglioma, pleomorphic xanthoastrocytoma, and papillary craniopharyngioma ( Figure 1

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Steven G. Waguespack and Gary Francis

during adolescence that is not seen in young children. 2 – 7 Most thyroid cancers in children are papillary (PTC), followed by follicular (FTC) and, more rarely, medullary carcinoma. 5 , 8 – 10 Subtypes of PTC include follicular variant, tall cell

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Dwight H. Owen, Bhavana Konda, Jennifer Sipos, Tom Liu, Amy Webb, Matthew D. Ringel, Cynthia D. Timmers, and Manisha H. Shah

, differentiated thyroid cancer (DTC). Yet, for both of these MKIs, acquired resistance is universal, adverse events are common, and no overall survival benefit has been demonstrated. Papillary thyroid cancer (PTC) is primarily driven by constitutive activation of

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Daniel Y. C. Heng and Toni K. Choueiri

and prognostic features among histologic subtypes of renal cell carcinoma . Am J Surg Pathol 2003 ; 27 : 612 – 624 . 5 Beck SD Patel MI Snyder ME . Effect of papillary and chromophobe cell type on disease-free survival after nephrectomy

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Maria A. Kouvaraki, Suzanne E. Shapiro, Jeffrey E. Lee, Douglas B. Evans, and Nancy D. Perrier

therapy for papillary and follicular thyroid cancer . J Clin Endocrinol Metab 2001 ; 86 : 1447 – 1463 . 3 Hay ID Thompson GB Grant CS . Papillary thyroid carcinoma managed at the Mayo Clinic during six decades (1940-1999): temporal trends in

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Angela Pecoraro, Giuseppe Rosiello, Stefano Luzzago, Marina Deuker, Franciska Stolzenbach, Zhe Tian, Shahrokh F. Shariat, Fred Saad, Alberto Briganti, Anil Kapoor, Cristian Fiori, Francesco Porpiglia, and Pierre I. Karakiewicz

clear-cell or papillary histologic subtype, and that a small minority harbored FG3–4 tumors. Our second hypothesis was that variant histology may be found in few if any such patients. Methods Data Source and Patient Selection Within the SEER database, 10

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Presenter: Lori J. Wirth

cancers (DTCs) fall under this category, and include follicular thyroid cancer, Hürthle cell carcinoma, poorly differentiated thyroid cancer (PDTC), and, the most common subtype, papillary thyroid cancer (PTC). ATC also falls under the classification of

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Robert I. Haddad, Christian Nasr, Lindsay Bischoff, Naifa Lamki Busaidy, David Byrd, Glenda Callender, Paxton Dickson, Quan-Yang Duh, Hormoz Ehya, Whitney Goldner, Megan Haymart, Carl Hoh, Jason P. Hunt, Andrei Iagaru, Fouad Kandeel, Peter Kopp, Dominick M. Lamonica, Bryan McIver, Christopher D. Raeburn, John A. Ridge, Matthew D. Ringel, Randall P. Scheri, Jatin P. Shah, Rebecca Sippel, Robert C. Smallridge, Cord Sturgeon, Thomas N. Wang, Lori J. Wirth, Richard J. Wong, Alyse Johnson-Chilla, Karin G. Hoffmann, and Lisa A. Gurski

, thyroid carcinoma occurs 2 to 3 times more often in women than in men and is currently the fifth most common malignancy diagnosed in women. 6 The main histologic types of thyroid carcinoma are (1) differentiated thyroid carcinoma (DTC; including papillary

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Elizabeth G. Grubbs and Douglas B. Evans

: demographic, clinical, and pathologic predictors of survival in 1252 cases . Cancer 2006 ; 107 : 2134 – 2142 . 2. Frazell EL Foote FW Jr . Papillary cancer of the thyroid; a review of 25 years of experience . Cancer 1958 ; 11 : 895 – 922

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R. Michael Tuttle, Douglas W. Ball, David Byrd, Gilbert H. Daniels, Raza A. Dilawari, Gerard M. Doherty, Quan-Yang Duh, Hormoz Ehya, William B. Farrar, Robert I. Haddad, Fouad Kandeel, Richard T. Kloos, Peter Kopp, Dominick M. Lamonica, Thom R. Loree, William M. Lydiatt, Judith McCaffrey, John A. Olson Jr., Lee Parks, John A. Ridge, Jatin P. Shah, Steven I. Sherman, Cord Sturgeon, Steven G. Waguespack, Thomas N. Wang, and Lori J. Wirth

Overview There are 3 main histologic types of thyroid carcinoma: differentiated (including papillary, follicular, and Hürthle), medullary, and anaplastic (aggressive undifferentiated tumor). Of 53,856 patients treated for thyroid carcinoma