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Robert A. Figlin, Elizabeth Brown, Andrew J. Armstrong, Wallace Akerley, Al B. Benson III, Harold J. Burstein, David S. Ettinger, Phillip G. Febbo, Matthew G. Fury, Gary R. Hudes, Merrill S. Kies, Eunice L. Kwak, Robert J. Morgan Jr., Joanne Mortimer, Karen Reckamp, Alan P. Venook, Frank Worden and Yun Yen

of more than 1.5 times the upper limit of the normal range Hemoglobin level below the lower limit of the normal range A corrected serum calcium level of more than 10 mg/dL (2.5 mmol/L) Less than 1 year from initial diagnosis of renal cell carcinoma to

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Localized Renal Cell Carcinoma Alpa Nick, MD, The University of Texas MD Anderson Cancer Center, Matched Pair Pharmacodynamics and Feasibility Study of Pembrolizumab in Combination with Chemotherapy in Frontline Ovarian Cancer The awardees responded to

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with Bortezomib in Previously Untreated Patients with Waldenström Macroglobulinemia.” Pazopanib is currently approved by the FDA to treat patients with advanced renal cell carcinoma. The research grant to NCCN will evaluate the effectiveness of

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Lainie Martin and Russell J. Schilder

): 455s . Abstract 5000 . 25. Hainsworth JD Sosman JA Spigel DR . Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib . J Clin Oncol 2005 ; 23 : 7889 – 7896 . 26. Herbst RS Johnson DH

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Louis Burt Nabors, Jana Portnow, Mario Ammirati, Henry Brem, Paul Brown, Nicholas Butowski, Marc C. Chamberlain, Lisa M. DeAngelis, Robert A. Fenstermaker, Allan Friedman, Mark R. Gilbert, Jona Hattangadi-Gluth, Deneen Hesser, Matthias Holdhoff, Larry Junck, Ronald Lawson, Jay S. Loeffler, Paul L. Moots, Maciej M. Mrugala, Herbert B. Newton, Jeffrey J. Raizer, Lawrence Recht, Nicole Shonka, Dennis C. Shrieve, Allen K. Sills Jr, Lode J. Swinnen, David Tran, Nam Tran, Frank D. Vrionis, Patrick Yung Wen, Nicole R. McMillian and Maria Ho

from SRS regardless of the number of brain metastases present. 10 , 11 Some brain metastases of radioresistant primary tumors, such as melanoma and renal cell carcinoma, have also been shown to achieve good local control with SRS. 12 Other predictors

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Muhammad Shaalan Beg, Sadia Saleem, Aslan Turer, Colby Ayers, James A. de Lemos, Amit Khera, Philipp E. Scherer and Susan G. Lakoski

. 17. Liao LM Weinstein SJ Pollak M . Prediagnostic circulating adipokine concentrations and risk of renal cell carcinoma in male smokers . Carcinogenesis 2013 ; 34 : 109 – 112 . 18. Aleksandrova K Boeing H Nothlings U . Inflammatory

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Andrew W. Hahn, Smith Giri, Dilan Patel, Heather Sluder, Ari Vanderwalde and Mike G. Martin

metastatic renal cell carcinoma and soft tissue sarcoma. 22 The results of 3 small clinical trials evaluating pazopanib in the treatment of metastatic UC are summarized in Table 2 . 23 – 25 The contrasting results of the trials evaluating pazopanib alone

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Katy K. Tsai, Neharika Khurana, Timothy McCalmont, Adil Daud, Boris Bastian and Iwei Yeh

off-label use of mTOR inhibitors currently approved for other indications (eg, everolimus in renal cell carcinoma, pancreatic neuroendocrine tumors, and breast cancer; temsirolimus in renal cell carcinoma) may have been a viable option. The splice site

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Endocrinopathies Associated With the Use of Immune Checkpoint Inhibitors in the First-Line Treatment of Advanced Renal Cell Carcinoma: a Systematic Review and Meta-Analysis Jahan Nusrat MD Mogollon-Duffo Francis MD Quirch Miguel MD Ball Somedeb MD Hardwicke Fred MD

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Antoni Ribas

. J Clin Invest 1996 ; 97 : 515 – 521 . 76. Figlin RA Thompson JA Bukowski RM . Multicenter, randomized, phase III trial of CD8(+) tumor-infiltrating lymphocytes in combination with recombinant interleukin-2 in metastatic renal cell