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.6004/jnccn.2015.0159 Buying In Winn Rodger J. MD 11 2015 13 13 11 11 1301 1301 1302 1302 0131301 10.6004/jnccn.2015.0160 Ewing Sarcoma in a Patient With Cowden Syndrome Chandhanayingyong Mod C. a b MD Bernthal Nicholas M. a MD

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Young Adults; Chronic Myelogenous Leukemia; Malignant Pleural Mesothelioma; Melanoma; Multiple Myeloma; Lung Cancer Screening; and Soft Tissue Sarcoma. NCCN is committed to developing a comprehensive patient library with support from the NCCN

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J. Sybil Biermann

Ewing’s sarcoma, and chondrosarcoma. Guidelines for managing these bone cancers are especially important, given the rarity of these neoplasms and most clinicians’ lack of familiarity with them, said J. Sybil Biermann, MD, Professor and Medical Director

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Lauren E. Kernochan and Rochelle L. Garcia

Edited by Kerrin G. Robinson

adenocarcinomas . Am J Clin Pathol 2004 ; 122 : 546 – 551 . 32 Jeffers MD Richmond JA Macaulay EM . Overexpression of the c-myc proto-oncogene occurs frequently in uterine sarcomas . Mod Pathol 1995 ; 8 : 701 – 704 . 33 Fujii H Yoshida

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2012 10 10 8 8 939 939 942 942 0100939 10.6004/jnccn.2012.0097 The First Documented Case of High-Grade Synovial Cell Sarcoma of the Rectum Hostetter Richard B. a MD Yan Min b MD Vaghefi Houman c MD, PhD Pennington Kenneth d MD

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Charles J. Gomer

, hypoxia-inducible factor-1α (HIF-1α) is a client protein linked to cancer. 3 Studies in a xenograft model of Kaposi sarcoma and in mouse mammary carcinoma cells and tumors have shown that PDT induces the increased expression of HIF-1α. 4 , 5 “In whatever

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Christopher K. Bichakjian, Thomas Olencki, Murad Alam, James S. Andersen, Daniel Berg, Glen M. Bowen, Richard T. Cheney, Gregory A. Daniels, L. Frank Glass, Roy C. Grekin, Kenneth Grossman, Alan L. Ho, Karl D. Lewis, Daniel D. Lydiatt, William H. Morrison, Kishwer S. Nehal, Kelly C. Nelson, Paul Nghiem, Clifford S. Perlis, Ashok R. Shaha, Wade L. Thorstad, Malika Tuli, Marshall M. Urist, Timothy S. Wang, Andrew E. Werchniak, Sandra L. Wong, John A. Zic, Nicole McMillian, Karin Hoffman and Maria Ho

®. Overview Dermatofibrosarcoma protuberans (DFSP) is an uncommon, low-grade sarcoma of fibroblast origin with an incidence rate of 4.2 to 4.5 cases per million persons per year in the United States. 1 , 2 Because of its slow-growing nature, definitive

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Eve Henry, Victor Villalobos, Lynn Million, Kristin C. Jensen, Robert West, Kristen Ganjoo, Alexandra Lebensohn, James M. Ford and Melinda L. Telli

develop sarcomas, early-onset breast cancer, brain tumors, leukemia, and adrenocortical carcinomas. 1 , 2 The lifetime risk of cancer in these patients is extraordinarily high with 50% of patients having a diagnosis of cancer by the age of 30 and 90% by

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Elizabeth Danielson and Patricia J. Goldsmith

at a major cancer center. This includes individuals: With uncommon and complex cancers such as brain tumors and sarcoma that are infrequently treated by most physicians; With cancers, such as lymphoma, that are difficult to diagnose and for

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updates existing ones. NCCN recently released a refreshed version of the NCCN Guidelines for Patients with Soft Tissue Sarcoma. Sarcomas represent approximately 1% of adults with cancer, with an estimated 13,000 people expected to be diagnosed in 2018. 2