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Nanruoyi Zhou, Maria A. Velez, Dwight Owen and Aaron E. Lisberg

chemotherapy (NSCLC: KN189), radiation (NSCLC: PACIFIC), or multikinase inhibitors (renal cell carcinoma: KN426). 25 – 27 A better understanding of the diagnosis and management of irAEs would be especially helpful in settings where treatment modalities have

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Daniel B. Brown

, radioembolization with yttrium-90 ( 90 Y) microspheres, and thermal ablation, are increasingly being used in the United States. Current indications for these treatments are part of several NCCN Guidelines. Ablation is the preferred treatment modality in renal cell

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Andrew b MD Lin Doris D.M. c MD, PhD Eberhart Charles G. b MD, PhD Grossman Stuart A. d MD 4 2018 16 16 4 4 343 343 347 347 10.6004/jnccn.2017.7052 Biallelic TSC2 Mutations in a Patient With Chromophobe Renal Cell Carcinoma

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People—An Underserved, Understudied Cancer Risk Population Obedin-Maliver Juno MD, MPH, MAS 11 2017 15 15 11 11 1305 1305 1308 1308 10.6004/jnccn.2017.7050 Exceptional Response to Temsirolimus in a Metastatic Clear Cell Renal Cell Carcinoma

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Sumanta K. Pal, Matthew I. Milowsky and Elizabeth R. Plimack

Over the past decade, several advances in systemic therapy for genitourinary cancers have occurred. Since 2005, a total of 7 agents have been approved for metastatic renal cell carcinoma (RCC) based on positive phase III trials. 1 Similarly, 4

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Agda Karina Eterovic, Ossama M. Maher, Joya Chandra, Ken Chen, Jason Huse and Wafik Zaky

. 19. Kato K Ijiri R Tanaka Y ., Metachronous renal cell carcinoma in a child cured of neuroblastoma . Med Pediatr Oncol 1999 ; 33 : 432 – 433 . 20. Tanaka M Kato K Gomi K . Perivascular epithelioid cell tumor with SFPQ/PSF-TFE3 gene

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Aatur D. Singhi, Siraj M. Ali, Jill Lacy, Andrew Hendifar, Khanh Nguyen, Jamie Koo, Jon H. Chung, Joel Greenbowe, Jeffrey S. Ross, Marina N. Nikiforova, Herbert J. Zeh, Inderpal S. Sarkaria, Anil Dasyam and Nathan Bahary

. ALK fusion genes, including EML4-ALK and STRN-ALK , have been identified in multiple cancer types, including lung adenocarcinoma, colorectal adenocarcinoma, breast cancer, renal cell carcinoma, renal medullary carcinoma, and papillary thyroid

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Donald A. Podoloff, Douglas W. Ball, Edgar Ben-Josef, Al B. Benson III, Steven J. Cohen, R. Edward Coleman, Dominique Delbeke, Maria Ho, David H. Ilson, Gregory P. Kalemkerian, Richard J. Lee, Jay S. Loeffler, Homer A. Macapinlac, Robert J. Morgan Jr., Barry Alan Siegel, Seema Singhal, Douglas S. Tyler and Richard J. Wong

cancer . Urology 2001 ; 57 : 108 – 111 . 70 Kang DE White RL Jr Zuger JH . Clinical use of fluorodeoxyglucose F 18 positron emission tomography for detection of renal cell carcinoma . J Urol 2004 ; 171 : 1806 – 1809 . 71

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Charles J. Ryan and Eric J. Small

patients with advanced renal cell carcinoma . Cancer Treat Rep 1980 ; 64 : 343 – 344 . 29 Pienta K Redman BG Esper PS . A phase II evaluation of oral tamoxifen and intermittent intravenous vinblastine in hormone-refractory adenocarcinoma of

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Peter E. Clark

appreciation of tumor heterogeneity. Ground-breaking work in renal cell carcinoma has shown significant differences in the molecular profile of the primary tumor and metastatic foci within the same patient. 5 Indeed, even within the primary tumor, the