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Stanford Comprehensive Cancer Center

Cervical carcinoma remains a health issue for women worldwide. Cervical cytology screening is the current method for early detection, and the NCCN Cervical Cancer Screening Clinical Practice Guidelines in Oncology provide direction for evaluating and managing this process, including clarified and revised recommendations on screening techniques and intervals and follow-up of abnormal screening results, including colposcopy. Human papillomavirus (HPV) DNA testing for primary cervical cancer has been approved by the FDA, and HPV DNA testing for high-risk virus types can also be used as a component of both primary screening and workup of abnormal cytology results. Colposcopy, along with colposcopically directed biopsies, has become the primary method for evaluating women with abnormal cervical cytologies. Special considerations for colposcopy performed during pregnancy are also discussed.

For the most recent version of the guidelines, please visit

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Dayna S. Early and Darrell M. Gray II

Colorectal cancer (CRC) is largely preventable using screening, primarily through detecting and removing adenomatous polyps during flexible sigmoidoscopy (FS) and colonoscopy, but also through identifying early-stage cancers with fecal occult

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Randall W. Burt

Screening for colon cancer in the general population 50 years of age and older, as outlined in the NCCN Clinical Practice Guidelines in Oncology in this volume, has been shown to substantially decrease mortality from this malignancy. 1 – 3

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Kristine A. Donovan, Teresa L. Deshields, Cheyenne Corbett and Michelle B. Riba

NCCN was among the first voices calling for routine screening of distress in patients with cancer. The first NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Distress Management were published in 1999. 1 Since then, a number of

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Warner K. Huh

With the introduction of widespread Pap smear screening starting in the 1940s, the United States has seen at least a 50% reduction in the incidence and mortality of invasive cervical cancer. In light of the ease of sampling, the long pre

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Elizabeth A. Rohan, Beth Slotman, Amy DeGroff, Kerry Grace Morrissey, Jennifer Murillo and Paul Schroy

colonoscopy screening in a medically disadvantaged population Ascertain PN intervention activities during colonoscopy screening most valued by patients that potentially improve patient outcomes Background Oncology patient navigation (PN) is

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James Mohler, Robert R. Bahnson, Barry Boston, J. Erik Busby, Anthony D'Amico, James A. Eastham, Charles A. Enke, Daniel George, Eric Mark Horwitz, Robert P. Huben, Philip Kantoff, Mark Kawachi, Michael Kuettel, Paul H. Lange, Gary MacVicar, Elizabeth R. Plimack, Julio M. Pow-Sang, Mack Roach III, Eric Rohren, Bruce J. Roth, Dennis C. Shrieve, Matthew R. Smith, Sandy Srinivas, Przemyslaw Twardowski and Patrick C. Walsh

cancer in men. 1 Experts generally believe that these changes resulted from prostate-specific antigen (PSA) screening that detected many early-stage prostate cancers. For example, the percentage of patients with low-risk disease has increased (45.3% in

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Sylvie D. Lambert, Brian Kelly, Allison Boyes, Alexander Cameron, Catherine Adams, Anthony Proietto and Afaf Girgis

distress screening programs in cancer care as a way of improving the management of distress. Routine distress screening at periods of increased vulnerability is now an integral part of international cancer control plans 7 , 8 and best practice guidelines

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Nila Alsheik, Zhaohui Su, Anna Lafontant, Gregory Donadio, Kathleen Troeger, Scott Pohlman, Melinda Talley, Vandana Menon and Emily Conant

Introduction: Screening mammography is a key component of secondary prevention programs targeting reductions in breast cancer mortality. The early detection of cancers facilitates treatment at a more curable, locoregionally limited stage. We

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Dawn J. Brooks

screening mammography and the benefits of adjuvant systemic therapies, the mortality rate due to breast cancer has decreased over the past 25 years. 2 Nonetheless, considerable professional disagreement exists over the most appropriate age at which to begin