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John A. Thompson

of these novel treatments, with recommendations for managing related toxicities. Importantly, the recommended systemic treatment options for metastatic or unresectable melanoma now include (depending on patient and disease characteristics

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Robert J. Morgan Jr

those things. Just like acupuncture. But I like to take vitamins. I read in Woman’s Day that some actresses recommend them.” The tools available to an oncologist for the purpose of treating cancer include surgery, radiation, and systemic treatments

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Peyman Haghighat and Tanios Bekaii-Saab

fluorouracil as systemic treatment for advanced gastric carcinoma: a randomized phase II trial of the Swiss Group for Clinical Cancer Research . J Clin Oncol 2007 ; 25 : 3217 – 3223 . 17. Ajani JA Fodor MB Tjulandin SA . Phase II multi

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Corey Cutler and Steven Z. Pavletic

-line systemic treatment of acute graft-versus-host disease: recommendations of the American Society of Blood and Marrow Transplantation . Biol Blood Marrow Transplant 2012 ; 18 : 1150 – 1163 . 10.1016/j.bbmt.2012.04.005 6. Harris AC , Young R , Devine

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Yi-Jen Chen

ablative RT to improve survival in patients with oligometastatic breast, lung, colorectal, and prostate cancers. Some experts believe that with effective systemic treatment, patients with oligometastases may not experience disease progression or may only

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Robert W. Carlson and on behalf of the NCCN Breast Cancer Panel

The past 10 years have witnessed multiple important advances in the systemic treatment of breast cancer ( Table 1 ). These advances have resulted from a better understanding of the underlying biology of breast cancer, the development of new

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James L. Mohler, Philip W. Kantoff, Andrew J. Armstrong, Robert R. Bahnson, Michael Cohen, Anthony Victor D’Amico, James A. Eastham, Charles A. Enke, Thomas A. Farrington, Celestia S. Higano, Eric Mark Horwitz, Mark H. Kawachi, Michael Kuettel, Richard J. Lee, Gary R. MacVicar, Arnold W. Malcolm, David Miller, Elizabeth R. Plimack, Julio M. Pow-Sang, Sylvia Richey, Mack Roach III, Eric Rohren, Stan Rosenfeld, Eric J. Small, Sandy Srinivas, Cy Stein, Seth A. Strope, Jonathan Tward, Patrick C. Walsh, Dorothy A. Shead and Maria Ho

eventually experience progression and require further treatment in the form of androgen deprivation therapy (ADT), chemotherapy, or other systemic treatments. Researchers estimate that prostate cancer will account for 29,720 deaths in 2013. ADT is the

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Presenters : Chad A. LaGrange, M. Dror Michaelson and Colleen H. Tetzlaff

receiving systemic treatment for metastatic RCC is complex and often entails multidisciplinary collaboration, emphasized Colleen H. Tetzlaff, MHS, PA-C, Fox Chase Cancer Center. To illustrate this, she discussed a case report of a 58-year-old man who

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Richard I. Fisher

III trial of R 2 versus rituximab/chemotherapy followed by rituximab maintenance in previously untreated, advanced FL requiring systemic treatment. Patients in the study were randomized to 1.5 years of R 2 followed by a third year of rituximab (n=513

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Sara E. Nunnery, Andrew E. Fintel, W. Clay Jackson, Jason C. Chandler, Michael O. Ugwueke and Mike G. Martin

States. CML can be well controlled with systemic treatment, but the cost can be daunting. 10 Oral tyrosine kinase inhibitors (TKIs) such as imatinib can control the disease long-term and are the initial treatment of choice. However, in the United