Cancer pain is unfortunately very prevalent, with opioids the mainstay of treatment. Knowledge of the types of pain caused by cancer and the effects of various opioids would be expected to improve pain therapy. This article addresses the use, side effects, formulations, and metabolism of the most commonly used opioids in cancer pain management, including morphine, codeine, hydrocodone, hydromorphone, fentanyl, and methadone. The role of opioid conversion and equipotent dosing when changing from one opioid to another is also described.
Andrea M. Trescot
Michael D. Stubblefield, Harold J. Burstein, Allen W. Burton, Christian M. Custodio, Gary E. Deng, Maria Ho, Larry Junck, G. Stephen Morris, Judith A. Paice, Sudhakar Tummala and Jamie H. Von Roenn
Neuropathy is a common, often debilitating complication of cancer and its treatment. Effective management of this disorder depends on early diagnosis and an understanding of its underlying causes in the individual patient. In January 2009, NCCN gathered a multidisciplinary group to review the literature and discuss intervention strategies currently available to patients as well as areas that require research efforts. The task force, which comprised experts in anesthesiology, medical oncology, neurology, neuro-oncology, neurophysiology, nursing, pain management, and rehabilitation, was charged with the goal of outlining recommendations for the possible prevention, diagnosis, and management of neuropathy. This report documents the proceedings of this meeting with a general background on neuropathy and neuropathy in oncology, followed by discussions on challenges and research issues, evaluation criteria, and management of different symptoms associated with this disorder.
Jimmie C. Holland and Barry D. Bultz
Lisa M. Stearns, Shane E. Brogan, Krisstin Hammond and Robert J. Spencer
Introduction World Health Organization guidelines identified inadequate cancer pain management as a global health concern, with the analgesic ladder developed to support stepwise progression to strong opioids as necessary. The 2018 National
Updates in Version 2.2013 of the NCCN Guidelines for Adult Cancer Pain from Version 2.2012 include: PAIN-1 Principles of Cancer Pain Management 1st bullet was modified as: “There is increasing evidence in oncology that survival is linked to
Judith A. Paice
“ Unrelieved pain is a public health crisis, and opioid misuse and overdose deaths are emergencies. These 2 crises have converged, and unintended consequences of efforts to squelch the opioid crisis have led to challenges in pain management
Raymond b MD Serrie Alain c MD, PhD 03 2013 11 11 suppl_1 suppl_1 S-11 S-11 S-16 S-16 011S-11 10.6004/jnccn.2013.0209 Provision of Palliative Care and Pain Management Services for Oncology Patients Marchetti Paolo a MD Voltz Raymond
compared with only 37.2% of the group whose pain was not as well controlled ( P =.06). Therefore, given the influence of pain as an independent predictor for survival, pain management, like hematologic parameters, should be controlled for in the conduct and
Pain Management: Important Adjuvants to Systemic Analgesics Eidelman Anthony MD White Traci MD Swarm Robert A. MD 09 2007 5 5 8 8 851 851 858 858 0050851 10.6004/jnccn.2007.0075