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Sujana Movva, Margaret von Mehren, Eric A. Ross and Elizabeth Handorf

Background Soft tissue sarcomas (STS) are uncommon tumors of the connective tissues. According to the current AJCC staging system, patients with stage III disease (large, deep, high-grade) have an expected overall survival (OS) of

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Rashmi Chugh

Sarcomas originating in the bone represent a challenge for physicians and patients. Because they constitute only 0.2% of all adult malignancies and 6% of pediatric malignancies, resources for studying this disease are often limited. 1 , 2 In the

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Brian P. Rubin and John R. Goldblum

manufacturers of any products discussed in the article or their competitors. References 1. Singh HK Kilpatrick SE Silverman JF . Fine needle aspiration biopsy of soft tissue sarcomas: utility and diagnostic challenges . Adv Anat Pathol 2004

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Judd E. Cummings, J. Andrew Ellzey and Robert K. Heck

2004 ; 429 : 286 – 291 . 8. Marcus RB Berrey BH Graham-Pole J . The treatment of Ewing's sarcoma of bone at the University of Florida: 1969 to 1998 . Clin Orthop Rel Res 2002 ; 397 : 290 – 297 . 9. Meyers PA Heller G Healey J

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Scott M. Schuetze and Michael E. Ray

Cancer J Clin 2004 ; 54 : 8 – 29 . 2 Pisters PW Leung DH Woodruff J . Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities . J Clin Oncol 1996 ; 14 : 1679 – 1689 . 3 Yang JC

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Justin M. M. Cates

Considerable changes in the clinical and pathologic staging of soft tissue sarcoma (STS) are presented in the 8th edition of the AJCC Cancer Staging Manual. 1 There are some obvious improvements, such as the creation of separate staging schemes

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James Saller, Christine M. Walko, Sherri Z. Millis, Evita Henderson-Jackson, Rikesh Makanji and Andrew S. Brohl

Background Kaposi sarcoma (KS) is an uncommon angioproliferative malignancy that is associated with human herpesvirus 8 (HHV-8). KS is most commonly observed in patients affected by HIV/AIDS, and is one of several AIDS-defining illnesses. It

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Scott M. Schuetze

for patients aged under 40 years with bone sarcoma in Britain, 1980–1994 . Br J Cancer 2006 ; 94 : 22 – 29 . 4. Bacci G Mercuri M Longhi A . Neoadjuvant chemotherapy for the treatment of osteosarcoma of the extremities: a comparison of

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Suzanne George

The past year has seen major changes in the treatment of soft tissue sarcomas (STSs), according to Suzanne George, MD, Associate Professor of Medicine, Harvard Medical School, and Co-Clinical Director, Center for Sarcoma and Bone Oncology, Dana

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David M. Thomas and Andrew J. Wagner

/print certificate. Learning Objectives Upon completion of this activity, participants will be able to: Identify molecular markers of giant-cell tumors of bone Describe the relevance of the p53 pathway in sarcoma Specify tumors that may