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James L. Mohler and the NCCN Prostate Cancer Panel

as “very low” risk and many men with “low” risk cancer are best served by careful “active surveillance.” Active surveillance seeks to deliver treatment only to those men who require it while avoiding the side effects of operation or radiation that was

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Randall W. Burt

defined genetically, and this genetic definition has allowed the elucidation of precise phenotypes for each of the conditions and the development of precise screening and surveillance guidelines based on both investigation and expert opinion. However, a

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Alison M. Lake and William W. Roberts

Clayman RV . Incision of the ureterovesical junction for endoscopic surveillance of transitional cell cancer of the upper urinary tract . J Urol 1993 ; 150 : 1440 – 1443 . 4. Lam JS Gupta M . Ureteroscopic management of upper tract

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James L. Mohler and Emmanuel S. Antonarakis

need to apply caution here. We believe active surveillance should be offered to men with favorable intermediate-risk prostate cancer, but this needs to be considered carefully,” he told the audience. Active surveillance in this setting may include a

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Randall W. Burt

syndrome have been identified, leaving the vast majority at great risk without appropriate screening. Proper physician knowledge concerning the application of testing and surveillance in inherited colon cancer is of great importance for cancer prevention

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Crystal S. Denlinger, Robert W. Carlson, Madhuri Are, K. Scott Baker, Elizabeth Davis, Stephen B. Edge, Debra L. Friedman, Mindy Goldman, Lee Jones, Allison King, Elizabeth Kvale, Terry S. Langbaum, Jennifer A. Ligibel, Mary S. McCabe, Kevin T. McVary, Michelle Melisko, Jose G. Montoya, Kathi Mooney, Mary Ann Morgan, Tracey O’Connor, Electra D. Paskett, Muhammad Raza, Karen L. Syrjala, Susan G. Urba, Mark T. Wakabayashi, Phyllis Zee, Nicole McMillian and Deborah Freedman-Cass

at NCCN.org ).These guidelines are not intended to provide guidance on the surveillance and follow-up requirements of a survivor’s primary cancer (see NCCN disease-specific guidelines, available at NCCN.org ), nor are they intended to provide

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Stacy Loeb and H. Ballentine Carter

Vickers et al 16 included heterogeneous studies of PSA kinetics both before and after a prostate cancer diagnosis to predict diverse outcomes ranging from biopsy outcome to progression on active surveillance. Studies have since shown that PSA kinetics may

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Thai H. Ho and Eric Jonasch

small tumors (<3 cm), independent of location or number of tumors, was developed to guide surveillance based on a 10-year follow-up study of parenchymal-sparing surgery in hereditary RCC. 28 Papillary RCC is hypoechoic and can be missed by ultrasound

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Samir Gupta, Dawn Provenzale, Scott E. Regenbogen, Heather Hampel, Thomas P. Slavin Jr, Michael J. Hall, Xavier Llor, Daniel C. Chung, Dennis J. Ahnen, Travis Bray, Gregory Cooper, Dayna S. Early, James M. Ford, Francis M. Giardiello, William Grady, Amy L. Halverson, Stanley R. Hamilton, Jason B. Klapman, David W. Larson, Audrey J. Lazenby, Patrick M. Lynch, Arnold J. Markowitz, Robert J. Mayer, Reid M. Ness, Niloy Jewel Samadder, Moshe Shike, Shajanpeter Sugandha, Jennifer M. Weiss, Mary A. Dwyer and Ndiya Ogba

with CRC, the panel recommends colonoscopy surveillance based on NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Colon Cancer and for Rectal Cancer (to view the most recent version of these guidelines, visit NCCN.org ). For carriers

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Kahee A. Mohammed, Leslie Hinyard, Martin W. Schoen, Christian J. Geneus, Eric S. Armbrecht, Fred R. Buckhold and Thomas E. Burroughs

VTE in hospitalized patients with cancer, ranging from 0.6% to 7.8%. 5 , 8 , 9 This inconsistency is likely due to heterogeneity of the cancer, sampling variability, and variation in VTE surveillance and outcome measures. 10 – 13 Major risk factors