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James L. Mohler and Emmanuel S. Antonarakis

need to apply caution here. We believe active surveillance should be offered to men with favorable intermediate-risk prostate cancer, but this needs to be considered carefully,” he told the audience. Active surveillance in this setting may include a

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Randall W. Burt

syndrome have been identified, leaving the vast majority at great risk without appropriate screening. Proper physician knowledge concerning the application of testing and surveillance in inherited colon cancer is of great importance for cancer prevention

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Crystal S. Denlinger, Robert W. Carlson, Madhuri Are, K. Scott Baker, Elizabeth Davis, Stephen B. Edge, Debra L. Friedman, Mindy Goldman, Lee Jones, Allison King, Elizabeth Kvale, Terry S. Langbaum, Jennifer A. Ligibel, Mary S. McCabe, Kevin T. McVary, Michelle Melisko, Jose G. Montoya, Kathi Mooney, Mary Ann Morgan, Tracey O’Connor, Electra D. Paskett, Muhammad Raza, Karen L. Syrjala, Susan G. Urba, Mark T. Wakabayashi, Phyllis Zee, Nicole McMillian and Deborah Freedman-Cass

at NCCN.org ).These guidelines are not intended to provide guidance on the surveillance and follow-up requirements of a survivor’s primary cancer (see NCCN disease-specific guidelines, available at NCCN.org ), nor are they intended to provide

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Stacy Loeb and H. Ballentine Carter

Vickers et al 16 included heterogeneous studies of PSA kinetics both before and after a prostate cancer diagnosis to predict diverse outcomes ranging from biopsy outcome to progression on active surveillance. Studies have since shown that PSA kinetics may

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Thai H. Ho and Eric Jonasch

small tumors (<3 cm), independent of location or number of tumors, was developed to guide surveillance based on a 10-year follow-up study of parenchymal-sparing surgery in hereditary RCC. 28 Papillary RCC is hypoechoic and can be missed by ultrasound

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Samir Gupta, Dawn Provenzale, Scott E. Regenbogen, Heather Hampel, Thomas P. Slavin Jr, Michael J. Hall, Xavier Llor, Daniel C. Chung, Dennis J. Ahnen, Travis Bray, Gregory Cooper, Dayna S. Early, James M. Ford, Francis M. Giardiello, William Grady, Amy L. Halverson, Stanley R. Hamilton, Jason B. Klapman, David W. Larson, Audrey J. Lazenby, Patrick M. Lynch, Arnold J. Markowitz, Robert J. Mayer, Reid M. Ness, Niloy Jewel Samadder, Moshe Shike, Shajanpeter Sugandha, Jennifer M. Weiss, Mary A. Dwyer and Ndiya Ogba

with CRC, the panel recommends colonoscopy surveillance based on NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Colon Cancer and for Rectal Cancer (to view the most recent version of these guidelines, visit NCCN.org ). For carriers

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Kahee A. Mohammed, Leslie Hinyard, Martin W. Schoen, Christian J. Geneus, Eric S. Armbrecht, Fred R. Buckhold and Thomas E. Burroughs

VTE in hospitalized patients with cancer, ranging from 0.6% to 7.8%. 5 , 8 , 9 This inconsistency is likely due to heterogeneity of the cancer, sampling variability, and variation in VTE surveillance and outcome measures. 10 – 13 Major risk factors

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Constance D. Lehman and Robert A. Smith

surveillance protocols appropriate to this elevated risk. However, clinicians were then faced with having to counsel women regarding options if a genetic mutation was identified, when few options were available at that time. Bilateral prophylactic mastectomies

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Eric Jonasch

is partial or radical nephrectomy or, in select patients, active surveillance. Further treatment is typically not recommended. “Following nephrectomy, adjuvant therapy for RCC has been an exercise in frustration,” he pointed out. Recent studies

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Masaki Shiota

guidelines, including the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Prostate Cancer, recommend active surveillance, radical therapy, or observation for nonmetastatic prostate cancer based on disease status and patient life expectancy