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Lynne I. Wagner, David Spiegel and Timothy Pearman

cancer patients: a meta-analysis . Cancer 2009 ; 115 : 5349 – 5361 . 33 Cohen L Cole SW Sood AK . Depressive symptoms and cortisol rhythmicity predict survival in patients with renal cell carcinoma: role of inflammatory signaling . PLoS

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Douglas Arenberg and Ella A. Kazerooni

upper abdominal malignancies. 23 In a recent study of more than 5200 individuals undergoing annual lung cancer screening with CT, 0.5% were diagnosed with an unsuspected extrapulmonary malignancy, most of which were renal cell carcinomas (44%), followed

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David Cella, Sarah K. Rosenbloom, Jennifer L. Beaumont, Susan E. Yount, Diane Paul, Debra Hampton, Amy P. Abernethy, Paul B. Jacobsen, Karen Syrjala and Jamie H. Von Roenn

. A comparison of the Renal Cell Carcinoma Symptom Index (RCC-SI) and the Functional Assessment of Cancer Therapy-Kidney Symptom Index (FKSI) . J Pain Symptom Manage 2009 ; 32 : 291 – 298 .

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Yuefeng Wang, Xinhua Yu, Nan Zhao, Jiajing Wang, Chi Lin, Enrique W. Izaguirre, Michael Farmer, Gary Tian, Bradley Somer, Nilesh Dubal, David L. Schwartz, Matthew T. Ballo and Noam A. VanderWalde

-cell lung cancer: a phase 3 randomised controlled trial . Lancet 2015 ; 385 : 36 – 42 . 11. Mickisch GH Garin A van Poppel H . Radical nephrectomy plus interferon-alfa-based immunotherapy compared with interferon alfa alone in metastatic renal-cell

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Amanda Putri Rahmadian, Seanthel Delos Santos, Shruti Parshad, Louis Everest, Matthew C. Cheung and Kelvin K. Chan

after stem-cell transplantation for multiple myeloma . N Engl J Med 2012 ; 366 : 1770 – 1781 . 10.1056/NEJMoa1114083 22571201 46. Motzer RJ , Escudier B , McDermott DF , . Nivolumab versus everolimus in advanced renal-cell carcinoma . N

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Michelle B. Riba, Kristine A. Donovan, Barbara Andersen, IIana Braun, William S. Breitbart, Benjamin W. Brewer, Luke O. Buchmann, Matthew M. Clark, Molly Collins, Cheyenne Corbett, Stewart Fleishman, Sofia Garcia, Donna B. Greenberg, Rev. George F. Handzo, Laura Hoofring, Chao-Hui Huang, Robin Lally, Sara Martin, Lisa McGuffey, William Mitchell, Laura J. Morrison, Megan Pailler, Oxana Palesh, Francine Parnes, Janice P. Pazar, Laurel Ralston, Jaroslava Salman, Moreen M. Shannon-Dudley, Alan D. Valentine, Nicole R. McMillian and Susan D. Darlow

, significant improvements in depression and self-reported aspects of quality of life were seen. An RCT for patients with renal cell carcinoma (n=277) showed that expressive writing reduces self-reported cancer-related symptoms (eg, pain, nausea, fatigue) and

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-term cohort, we identified 57 patients with a median of 36.7 months follow-up after aPD-1 treatment initiation, including 31 with melanoma, 12 with non–small cell lung cancer (NSCLC), and 14 with renal cell carcinoma (RCC). Of these, only 4 died during the

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George D. Demetri, Scott Antonia, Robert S. Benjamin, Marilyn M. Bui, Ephraim S. Casper, Ernest U. Conrad III, Thomas F. DeLaney, Kristen N. Ganjoo, Martin J. Heslin, Raymond J. Hutchinson, John M. Kane III, G. Douglas Letson, Sean V. McGarry, Richard J. O'Donnell, I. Benjamin Paz, John D. Pfeifer, Raphael E. Pollock, R. Lor Randall, Richard F. Riedel, Karen D. Schupak, Herbert S. Schwartz, Katherine Thornton, Margaret von Mehren and Jeffrey Wayne

sunitinib targets vascular endothelial growth factor receptor. However, the risk is higher in patients with renal cell carcinoma than in those with non–renal cell carcinoma. 160 Recent reports have shown that sunitinib is also associated with cardiotoxicity

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Kelly G. Paulson and Shailender Bhatia

renal cell carcinoma, 56 this strategy by itself is highly unlikely to be successful in overcoming MCC resistance to the PD-1/PD-L1 pathway blockade. Hence, we do not recommend trying the same outside of a clinical trial. However, there may be value in

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Mellar P. Davis

– 131 . 64. Van den Hove LE Van Gool SW Van Poppel H . Phenotype, cytokine production and cytolytic capacity of fresh (uncultured) tumour-infiltrating T lymphocytes in human renal cell carcinoma . Clin Exp Immunol 1997 ; 109 : 501 – 509