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Ami Vyas, S. Suresh Madhavan, Usha Sambamoorthi, Xiaoyun (Lucy) Pan, Michael Regier, Hannah Hazard, and Sita Kalidindi

.6 billion USD in the SEER-Medicare population, of which female breast cancer (BC) constituted the highest proportion at 13% ($16.5 billion). Further, it is projected to increase by 32% in 2020, presenting a significant burden to Medicare. 1 Of the $16

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Jing Xi, Aabha Oza, Shana Thomas, Foluso Ademuyiwa, Katherine Weilbaecher, Rama Suresh, Ron Bose, Mathew Cherian, Leonel Hernandez-Aya, Ashley Frith, Lindsay Peterson, Jingqin Luo, Jairam Krishnamurthy, and Cynthia X. Ma

Background It is estimated that >150,000 patients were living with metastatic breast cancer (MBC) in the United States in 2017. 1 Although progress in treatment strategies has led to significant improvement in overall survival in recent years, 1

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Alyssa G. Rieber and Richard L. Theriault

carcinoma of the mamma: suggestions for a new method of treatment, with illustrative cases . Lancet 1896 ; 2 : 104 – 107 . 2 Fisher B Costantino JP Wickerham DL . Tamoxifen for prevention of breast cancer: report of the National Surgical

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Anne A. Eaton, Camelia S. Sima, and Katherine S. Panageas

-label use is associated with increased rates of hospitalization and emergency department (ED) admission in a cohort of elderly Medicare beneficiaries diagnosed with breast cancer. To focus on use that could be considered “inappropriate,” we differentiate

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Michele Dabrowski, Kenneth Boucher, John H. Ward, Margaret M. Lovell, Angela Sandre, Janet Bloch, Lynne Carlquist, Monica Porter, Larry Norman, and Saundra S. Buys

A study was conducted to describe our group's experience using the NCCN Distress Thermometer in an outpatient breast cancer clinic. The NCCN Distress Thermometer was administered to patients attending the breast cancer clinic at Huntsman Cancer Institute during a 4-month period. Effects of disease, treatment, and demographic variables on distress level were analyzed. Patients reporting high distress were contacted by a social worker to determine the cause of the distress. Two hundred and eighty-six (286) subjects completed 403 questionnaires, with 96 patients (34%) reporting high levels of distress (5 or greater on a 10-point scale). No relationship was seen between high distress and stage of disease, type of current treatment, time since diagnosis, age, or other demographic factors. Underlying mental health disorders were associated with a higher level of distress. The Distress Thermometer was a useful method to screen, triage, and prioritize patient interventions. In our experience, the tool promoted communication between the patient and the health care team, which enhanced treating psychosocial and physical symptoms. Methods to optimize the use of this screen are proposed.

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Melinda L. Telli, William J. Gradishar, and John H. Ward

Greater Emphasis on Multigene Testing, Ovarian Suppression The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Breast Cancer now emphasize ovarian suppression in premenopausal women, as described by Melinda L. Telli, MD; the

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Natasha Hunter, Sarah Croessmann, Karen Cravero, Daniel Shinn, Paula J. Hurley, and Ben Ho Park

the feasibility of cfDNA for serial monitoring. 5 For example, we and others have demonstrated that ddPCR can detect MRD using cfDNA in patients with early-stage breast cancer after curative-intent therapies. 1 , 3 In addition, we are testing the

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Andrea K. Ng and Lois B. Travis

F emale breast cancer is a well-documented late effect of exposure to doses of ionizing radiation as low as 0.1 to 0.5 Sievert (Sv). 1 Sievert is the unit dose equivalent and the product of the absorbed dose in gray and quality factors; in this

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Eleni Linos and Walter C. Willett

This research was supported by the National Cancer Institute training grant R25 CA098566. References 1. Stanford JL Herrinton LJ Schwartz SM . Breast cancer incidence in Asian migrants to the United States and their

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William Gradishar and Kilian E. Salerno

Important “Tweaks” in Early-Stage Breast Cancer Guidelines Updates to the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Breast Cancer were relatively minor, according to William Gradishar, MD, the Betsy Bramsen Professor