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Daniëlle D. Huijts, Onno R. Guicherit, Jan Willem T. Dekker, Julia T. van Groningen, Leti van Bodegom-Vos, Esther Bastiaannet, Johannes A. Govaert, Michel W. Wouters, and Perla J. Marang-van de Mheen

Background Although surgery has a crucial role in colorectal cancer (CRC) treatment, it is associated with considerable risks of postoperative complications and mortality 1 , 2 and a resultant increase in healthcare costs. 3 Severe complications

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Matthew P. Banegas, Linda C. Harlan, Bhupinder Mann, and K. Robin Yabroff

treated for localized disease, and nearly 30% will be diagnosed with metastatic disease. 2 While surgery remains the primary treatment for localized RCC, 3 treatment options for metastatic RCC have changed markedly in the past decade. Before 2005

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Leigh Selesner, Gabrielle Gauvin, Dorotea Mutabdzic, Eileen O’Halloran, Maxwell Kilcoyne, Kwan-Keat Ang, Jeffrey Farma, Elin Sigurdson, and Sanjay Reddy

Introduction: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CS/HIPEC) has led to improved survival in select patients with peritoneal surface malignancies. Predicting the volume of disease and any unresectable disease is

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Robert E. Glasgow, David H. Ilson, James A. Hayman, Hans Gerdes, Mary F. Mulcahy, and Jaffer A. Ajani

patients have distant metastatic disease, extraregional nodal disease, or T4b tumors (involvement of the heart, great vessels, trachea), or are unable to tolerate surgery or multimodality therapy because of insufficient functional status. Even with optimal

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Quan P. Ly and Aaron R. Sasson

. Histopathologic validation of lymph node staging with FDG-PET scan in cancer of the esophagus and gastroesophageal junction: a prospective study based on primary surgery with extensive lymphadenectomy . Ann Surg 2000 ; 232 : 743 – 752 . 9. Yun M Lim

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Joyce Y. Wong and Vernon K. Sondak

Acceptable Option for Invasive Melanoma? Mohs micrographic surgery, traditionally considered contraindicated for invasive melanomas, has been studied in melanoma in situ, particularly in cosmetically sensitive areas such as the head and neck. Using this

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Katya Losk, Ines Vaz-Luis, Kristen Camuso, Rafael Batista, Max Lloyd, Mustafa Tukenmez, Mehra Golshan, Nancy U. Lin, and Craig A. Bunnell

delays in adjuvant chemotherapy initiation greater than 49 to 90 days after surgery may be associated with inferior outcomes, particularly among patients with triple-negative breast cancer (TNBC), HER2-positive subtypes, and higher-stage tumors. 7 – 12 A

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Carlotta Palumbo, Francesco A. Mistretta, Sophie Knipper, Angela Pecoraro, Zhe Tian, Shahrokh F. Shariat, Fred Saad, Claudio Simeone, Alberto Briganti, Alessandro Antonelli, and Pierre I. Karakiewicz

probability of survival for x additional years, given y years of accumulated survival. EFS time points used in the CS models consisted of from 1 year up to 10 years after surgery. Second, separate multivariable Cox regression (MCR) models predicting CSM

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Siyana Kurteva, Robyn Tamblyn, and Ari Meguerditchian

of cancer patients having undergone surgery in Montreal (Quebec) to describe their post-discharge opioid use and identify potential patterns of unplanned health service use (ED visits, hospitalizations). Provincial health administrative claims were

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Paul F. Engstrom, Juan Pablo Arnoletti, Al B. Benson III, Jordan D. Berlin, J. Michael Berry, Yi-Jen Chen, Michael A. Choti, Harry S. Cooper, Raza A. Dilawari, Dayna S. Early, Peter C. Enzinger, Marwan G. Fakih, James Fleshman Jr., Charles Fuchs, Jean L. Grem, James A. Knol, Lucille A. Leong, Edward Lin, Mary F. Mulcahy, Eric Rohren, David P. Ryan, Leonard Saltz, David Shibata, John M. Skibber, William Small Jr., Constantinos Sofocleous, James Thomas, Alan P. Venook, and Christopher Willett

or presence of regional nodal metastasis. However, because initial therapy of anal cancer does not typically involve surgery, true lymph node status may not be determined accurately. Biopsy of inguinal nodes is recommended if tumor metastasis to these