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Michaela J. Higgins, James M. Rae, David A. Flockhart, Daniel F. Hayes, and Vered Stearns

This work was supported in part by a Pharmacogenetics Research Network Grant # U-01 GM61373 (DAF) and by the Fashion Footwear Charitable Foundation of New York/QVC Presents Shoes on Sale™ (DFH). References 1 Early Breast Cancer

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Lee S. Schwartzberg and Sarah L. Blair

patients, according to the Early Breast Cancer Trialists' Collaborative Group meta-analysis. 12 Furthermore, in the MA.17 study, an additional 5 years of letrozole after Figure 1. Decision-making for chemotherapy in elderly women. Abbreviations

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William Gradishar and Kilian E. Salerno

, infraclavicular region, internal mammary nodes, and any part of the axillary bed considered at risk. The recommendations largely rely on data from the Early Breast Cancer Trialists' Collaborative Group (EBCTCG) meta-analysis 13 and the 2 most recent trials

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Shaneli A. Fernando and Stephen B. Edge

chemotherapy: 20-year results of the British Columbia randomized trial . J Natl Cancer Inst 2005 ; 97 : 116 – 126 . 11. Favourable and unfavourable effects on long-term survival of radiotherapy for early breast cancer: an overview of the

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Benjamin O. Anderson

Organization ; 2005 . p . 2 . Available at http://www.who.int/cancer/eb1143/en/ . 5. Goldhirsch A Glick JH Gelber RD . Meeting highlights: international expert consensus on the primary therapy of early breast cancer 2005 . Ann Oncol 2005

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Della F. Makower, Christine Brezina Weldon, Julia R. Trosman, Kent Hoskins, Cathleen Schaeffer, Bruce D. Rapkin, Melissa A. Simon, Al B. Benson, and William J. Gradishar

felt not in control of care”, p=0.0166. Of patients who received care sequence plans, 90% (45/50) found plan very useful or useful. Conclusion: Our project showed that the 4R model is a promising patient self-management method providing early breast

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Alison K. Conlin and Andrew D. Seidman

Genentech Inc. References 1. Early Breast Cancer Trialists' Collaborative Group . Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials . Lancet 2005

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Betsy L. Althaus

Marolla P . Impact of five prophylactic filgrastim schedules on hematologic toxicity in early breast cancer patients treated with epirubicin and cyclophosphamide . J Clin Oncol 2005 ; 23 : 6908 – 6918 . 12. Djulbegovic B Frohlich A Bennett

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Benjamin O. Anderson and Robert W. Carlson

. Veronesi U Cascinelli N Mariani L . Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer . N Engl J Med 2002 ; 347 : 1227 – 1232 . 13. Nadkarni MS Gupta PB Parmar VV

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Katya Losk, Ines Vaz-Luis, Kristen Camuso, Rafael Batista, Max Lloyd, Mustafa Tukenmez, Mehra Golshan, Nancy U. Lin, and Craig A. Bunnell

Background Over the past 50 years, substantial reductions in early breast cancer mortality have been documented due to a combination of earlier detection and to advances in adjuvant treatment. 1 – 4 In particular, adjuvant chemotherapy has