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Shailender Bhatia and John A. Thompson

as surgery or radiation therapy, may provide palliation of symptoms caused by local tumor growth, the cornerstone of treatment for metastatic melanoma is systemic therapy to address the clinical and subclinical sites of metastases. Chemotherapeutic

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Al B. Benson, Michael I. D’Angelica, Daniel E. Abbott, Daniel A. Anaya, Robert Anders, Chandrakanth Are, Melinda Bachini, Mitesh Borad, Daniel Brown, Adam Burgoyne, Prabhleen Chahal, Daniel T. Chang, Jordan Cloyd, Anne M. Covey, Evan S. Glazer, Lipika Goyal, William G. Hawkins, Renuka Iyer, Rojymon Jacob, R. Kate Kelley, Robin Kim, Matthew Levine, Manisha Palta, James O. Park, Steven Raman, Sanjay Reddy, Vaibhav Sahai, Tracey Schefter, Gagandeep Singh, Stacey Stein, Jean-Nicolas Vauthey, Alan P. Venook, Adam Yopp, Nicole R. McMillian, Cindy Hochstetler, and Susan D. Darlow

this disease, patients need careful consideration of treatment choice given the risk of potential toxicities from treatment and potential benefits. Surgery Partial hepatectomy is a potentially curative therapy for patients with a solitary tumor of

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Rajinder S. Grover, Kemp Kernstine, and Amrita Krishnan

performance status, and quick wound healing, which allowed her to receive chemotherapy within 4 weeks of the esophageal surgery. In an alternate scenario, if this patient had only undergone superficial parotidectomy, she would have been treated as stage IV

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Presenters: Crystal S. Denlinger, Kristina A. Matkowskyj, and Mary F. Mulcahy

newly diagnosed patients, postoperative therapy with nivolumab after preoperative chemoradiation and surgery in patients who have achieved R0 resections but have residual disease is a category 1 recommendation. For the first-line treatment of advanced

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Stephanie A. Morris, Dorothy Farrell, and Piotr Grodzinski

detect and diagnose early-stage cancers, identify metastases noninvasively, and guide tumor removal during surgery. For image-guided surgery, the use of targeted nanoparticles to identify lesions has been an active area of investigation. In general

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Elizabeth R. Kessler, Janet B. Kukreja, Christopher L. Geiger, and Stacy M. Fischer

validated tools ( Table 1 ). Multiple studies have found that the CGA is more sensitive than performance status in determining functional impairment and risks associated with chemotherapy or surgery. 5 The CGA can uncover age-related issues in up to 50% of

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Yue Chen, Zi-Qi Zheng, Fo-Ping Chen, Jian-Ye Yan, Xiao-Dan Huang, Feng Li, Ying Sun, and Guan-Qun Zhou

, accounting for 25% of malignant tumors in the major salivary glands and 50% in the minor glands. 2 The natural disease process is characterized by prolonged progression and multiple recurrences. 3 , 4 Surgery has been considered the most important treatment

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Karam Khaddour, Michael R. Chicoine, Jiayi Huang, Sonika Dahiya, and George Ansstas

squamous epithelial cells (original magnification, ×20). At his follow-up visit 5 months after the surgery, the patient continued to have persistent headaches and peripheral vision loss, but they were milder than the initial symptoms reported before surgery

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Pankaj Singhal and Shashikant Lele

Gynecologic Oncology Group study . J Clin Oncol 2003 ; 21 : 3194 – 3200 . 4. Hoskins WJ McGuire WP Brady MF . The effect of diameter of largest residual disease on survival after primary cytoreductive surgery in patients with suboptimal residual

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Patrick Ross Jr

“Photodynamic therapy (PDT) is not just a palliative treatment,” declared Patrick Ross, Jr, MD, PhD, Director, Division of Thoracic Surgery, The Ohio State University (OSU), Columbus, Ohio. “The real bang for the buck with PDT has got to be