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Mamta Mehta and Moshe Shike

vegetable intake and CRC risk may be weakened when adjusting for potential confounders such as physical activity, obesity, alcohol consumption, and smoking. 37 , 38 Because of the serious methodologic difficulties in studying the effects of fiber and the

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Elizabeth A. Rohan, Julie S. Townsend, Temeika L. Fairley, and Sherri L. Stewart

long-term care and follow-up. Clinical studies of cancer survivors have shown that comorbidities, such as obesity, and health behaviors, such as physical inactivity and heavy smoking, greatly influence overall quality of life and long-term survival of

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Neelima Denduluri, Debra A. Patt, Yunfei Wang, Menaka Bhor, Xiaoyan Li, Anne M. Favret, Phuong Khanh Morrow, Richard L. Barron, Lina Asmar, Shanmugapriya Saravanan, Yanli Li, Jacob Garcia, and Gary H. Lyman

eFigure 1 ). For most tumor types, the incidences of reduced RDI were higher in older patients (age ≥65 years), in obese patients (body surface area [BSA] >2 m 2 ), and in patients whose daily activities were restricted (ECOG performance status ≥1

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Michael D. DeVita, Andrew M. Evens, Steven T. Rosen, Paul A. Greenberger, and Adam M. Petrich

with relapsed sALCL Review the options for desensitization in patients with relapsed or refractory sALCL and hypersensitivity to brentuximab vedotin Case Report A 32-year-old woman with a medical history of super obesity (body mass index

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Marsha Reyngold, Joyce Niland, Anna ter Veer, Dana Milne, Tanios Bekaii-Saab, Steven J. Cohen, Lily Lai, Deborah Schrag, John M. Skibber, William Small Jr, Martin Weiser, Neal Wilkinson, and Karyn A. Goodman

factors associated with nonadherence to guidelines. An interesting finding in this study was the inverse association between BMI and RT omission. Despite concerns that obesity may contribute to higher rates of complications from pelvic RT and subsequent

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Joleen M. Hubbard and Axel Grothey

women from 1998 to 2009, largely attributed to be an effect of CRC screening. 3 Etiology The exact cause for this alarming trend in young adults is unclear, but has largely been attributed to dietary factors and the rising rate of obesity among

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Anusha Ponduri, David Z. Liao, Nicolas F. Schlecht, Gregory Rosenblatt, Michael B. Prystowsky, Rafi Kabarriti, Madhur Garg, Thomas J. Ow, Bradley A. Schiff, Richard V. Smith, and Vikas Mehta

obese (BMI >30 kg/m 2 ), and advanced age (≥70 years). Individualized reasons for S-PORT delay, including those related and unrelated to treatment, were also identified through chart review. Although we previously established a negative impact of

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The UNMC Eppley Cancer Center at The Nebraska Medical Center

An estimated 38,890 Americans will be diagnosed with kidney cancer and 12,840 will die of this disease in the United States in 2006. Renal cell carcinoma (RCC) constitutes approximately 2% of all malignancies, with a median age at diagnosis of 65 years. Smoking and obesity are among the risk factors for RCC development, and tumor grade, local extent of the tumor, presence of regional nodal metastases, and evidence of metastatic disease at presentation are the most important prognostic determinants of 5-year survival. These guidelines discuss evaluation, staging, treatment, and management after treatment.

For the most recent version of the guidelines, please visit NCCN.org

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William J. Ellis and Paul H. Lange

Robotic-assisted laparoscopic radical prostatectomy is now one of the most common ways to treat prostate cancer. Although it is undoubtedly an outstanding procedure, in many contexts the advantages of the laparoscopic approach are overstated. The authors believe that open radical prostatectomy will continue to have an important role. For example, an extensive lymphadenectomy is more easily accomplished with the open technique and may be important in staging and possibly curing patients at high risk for prostate cancer. Also, tactile sensation is a valuable asset in assessing the extent of local tumor, and this cannot yet be replicated with a robotic approach. Furthermore, obese patients, those with a history of extensive prior surgical procedures, and men with extremely large prostates may experience advantages with the open technique. Finally, the open approach has a significant advantage in terms of hospital costs.