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John G. Huff

Although palpable and mammographic breast masses are common and frequently reflect underlying fibrocystic change, they must be distinguished from breast malignancy. Clinical characterization of these masses is often unreliable, and mammographic appearances alone cannot distinguish between those that are solid and those that are cystic. Sonography is an important adjunct to characterize these abnormalities further. Management of solid masses is well established, but overlap in appearance of cystic lesions has led to variability in reporting and management. With current high-resolution ultrasound, specific observations can accurately characterize most cystic masses, thereby facilitating management decisions.

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Amy Ly, Jill C. Ono, Kevin S. Hughes, Martha B. Pitman and Ronald Balassanian

the FNAB sample was routinely performed to ensure specimen adequacy. Cases were entered into the study if the masses were treated neoadjuvantly and/or were subsequently excised, and all breast mass–related care occurred at a single hospital. Patient

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Lauren Nye, Timothy K. Huyck and William J. Gradishar

delayed because neither patient nor physician suspects malignancy. This report presents a recent case of a young primigravid woman with a newly appreciated breast mass seen at Northwestern University Feinberg School of Medicine as a means of discussing

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Therese B. Bevers

breast mass found it by chance and not during BSE; however, virtually none of the reported studies distinguished the method of self-detection. In addition, many women report they do not practice BSE because they “don't know how to do it”. Clearly, the

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Peter B. Bach, Stephen B. Edge, Linda House, Jennifer Malin, James L. Mohler and Clifford Goodman

. Edge concurred, having recently seen a patient reject a biopsy for a breast mass because she did not have $250. Luckily, his institution subsequently found a way to get the woman her biopsy. Dr. Bach remarked, “In the wealthiest country in the world, we

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Noa Efrat Ben-Baruch, Ron Bose, Shyam M. Kavuri, Cynthia X. Ma and Matthew J. Ellis

treated with oophorectomy, letrozole, and zoledronic acid, and experienced an excellent clinical and radiologic response. In 2005, a new breast mass was found in the same breast and biopsy results revealed invasive ductal carcinoma that was hormone

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Natasha Hunter, Sarah Croessmann, Karen Cravero, Daniel Shinn, Paula J. Hurley and Ben Ho Park

risk versus benefit of ongoing maintenance therapy for patients with metastatic disease who experience extreme responses to treatment. Case Report A premenopausal woman aged 39 years presented in 2008 with a left-sided breast mass that was further

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Therese B. Bevers, Mark Helvie, Ermelinda Bonaccio, Kristine E. Calhoun, Mary B. Daly, William B. Farrar, Judy E. Garber, Richard Gray, Caprice C. Greenberg, Rachel Greenup, Nora M. Hansen, Randall E. Harris, Alexandra S. Heerdt, Teresa Helsten, Linda Hodgkiss, Tamarya L. Hoyt, John G. Huff, Lisa Jacobs, Constance Dobbins Lehman, Barbara Monsees, Bethany L. Niell, Catherine C. Parker, Mark Pearlman, Liane Philpotts, Laura B. Shepardson, Mary Lou Smith, Matthew Stein, Lusine Tumyan, Cheryl Williams, Mary Anne Bergman and Rashmi Kumar

highly suggestive of malignancy (BI-RADS 5). Fine-Needle Aspiration (FNA) Biopsy: An FNA biopsy involves use of a smaller bore needle to obtain cytologic samples from a breast mass. Advantages of FNA biopsy include its minimally invasive methodology

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Saranya Chumsri, Ethan S. Sokol, Aixa E. Soyano-Muller, Ricardo D. Parrondo, Gina A. Reynolds, Aziza Nassar and E. Aubrey Thompson

Case Presentation A white woman aged 66 years initially presented with a large fungating right breast mass with bleeding requiring blood transfusion. CT scan of the chest, abdomen, and pelvis showed a 14-cm mass in her right breast along with bulky

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Scott V. Bratman, Kathleen C. Horst, Robert W. Carlson and Daniel S. Kapp

middle-aged patient with Down syndrome presented to his physician with a palpable 5-cm mass in the upper-inner quadrant of the left breast. He was a non-smoker and had no known family history of cancer. A diagnostic mammogram showed a left-sided breast