expert opinion. The complete details of the development and update of the NCCN Guidelines are available on the NCCN website ( NCCN.org ). Initial Presentation Patients with DLBCL and BL may present with fever, chills, night sweats, unexplained
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Kimberly Davies, Matthew Barth, Saro Armenian, Anthony N. Audino, Phillip Barnette, Branko Cuglievan, Hilda Ding, James B. Ford, Paul J. Galardy, Rebecca Gardner, Rabi Hanna, Robert Hayashi, Alexandra E. Kovach, Andrea Judit Machnitz, Kelly W. Maloney, Lianna Marks, Kristin Page, Anne F. Reilly, Joanna L. Weinstein, Ana C. Xavier, Nicole R. McMillian, and Deborah A. Freedman-Cass
William G. Wierda, John C. Byrd, Jeremy S. Abramson, Seema Bhat, Greg Bociek, Danielle Brander, Jennifer Brown, Asher Chanan-Khan, Steve E. Coutre, Randall S. Davis, Christopher D. Fletcher, Brian Hill, Brad S. Kahl, Manali Kamdar, Lawrence D. Kaplan, Nadia Khan, Thomas J. Kipps, Jeffrey Lancet, Shuo Ma, Sami Malek, Claudio Mosse, Mazyar Shadman, Tanya Siddiqi, Deborah Stephens, Nina Wagner, Andrew D. Zelenetz, Mary A. Dwyer, and Hema Sundar
GCSFs might be considered in patients with severe neutropenic fever after chemotherapy. HBV Reactivation: HBV reactivation leading to fulminant hepatitis, hepatic failure, and death have been reported in patients receiving chemotherapy and
Jeffrey A. Gilreath, David D. Stenehjem, and George M. Rodgers
be given in 1 to 4 injections for children with iron-deficiency anemia. This method was appealing to clinicians because the reported incidence of reactions was on the order of only 1% and included symptoms such as fever, arthralgia, and
cancer survivors between time points and distress the areas of eating ( P <.04), fatigue ( P <.01), fevers ( P <.02), getting around ( P <.05), mouth sores ( P <.05), congestion ( P <.02), sleep ( P <.02), fears ( P =.05), nervousness ( P =.04), physical
Scott M. Lindhorst, Richard D. Lopez, and Ronald D. Sanders
woman presented with several weeks of progressive fatigue, bruising, and eventually the development of fevers. She had no prior medical problems and took no medications. Physical examination revealed only moderate splenomegaly, measuring 14 cm. On
Matthew Zibelman and Anthony J. Olszanski
, dysphagia, or dyspnea. He reported no significant weight loss, fevers, or chills, and had not noticed any other masses or unusual skin lesions. He did report mild fatigue. A brief trial of antibiotics was prescribed by a primary care physician but did not
Rajinder S. Grover, Kemp Kernstine, and Amrita Krishnan
56-year-old woman noted a slowly enlarging right parotid mass for approximately 2 months. She denied any fever, night sweats, decreased salivation, dry eyes, pain, or facial paresthesias. She had an intentional weight loss of about 19 pounds over the
Matthew Ulrickson, Fred Okuku, Victoria Walusansa, Oliver Press, Sam Kalungi, David Wu, Fred Kambugu, Corey Casper, and Jackson Orem
Mulago Hospital reporting a 7-year history of gradually increasing pruritus and diffuse, scaly skin lesions ( Figure 1A ). More recently he reported mild weight loss and anorexia, although he denied having drenching night-sweats or fevers. He denied any
Jarred Burkart, Dwight Owen, Manisha H. Shah, Sherif R. Z. Abdel-Misih, Sameek Roychowdhury, Robert Wesolowski, Sigurdis Haraldsdottir, Julie W. Reeser, Eric Samorodnitsky, Amy Smith, and Bhavana Konda
onset abdominal pain and fevers, and imaging results were concerning for abscess formation at the anastomotic site. He underwent exploratory laparotomy, ileocolostomy resection, and abdominal washout with wide drainage for ileocolostomy perforation
Chelsea C. Pinnix, Valerie Reed, and Bouthaina Dabaja
abdominal pain resolved after recent administration of a proton pump inhibitor. She denied gastrointestinal symptoms. She denied melena, nausea, vomiting, anorexia, unintentional weight loss, fevers, and night sweats. Her medical history was notable for HT