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NCCN News

dedicated to empowering patients. By expanding the availability of this information, it will increase awareness in genetic testing, share tools for a more proactive approach to health, and provide greater access to genetic counseling and testing, ultimately

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Management of Patients With Nonmetastatic Prostate Cancer

Presented by: Julio M. Pow-Sang

/or potential risk of cancer in family members. If these criteria are met, germline multigene testing should include at least BRCA1 , BRCA2 , ATM , PALB2 , CHEK2 , MLH1 , MSH2 , MSH6 , and PMS2 . Posttest genetic counseling is strongly recommended if

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Keynote Session: Reducing Racial Disparities in Oncology—Recommendations for Implementing Guideline-Adherent Cancer Care

Presented by: Shonta Chambers, Elizabeth Harrington, Lisa A. Lacasse, Robert Winn, and moderated by Alyssa A. Schatz

-related genetic counseling and testing . J Genet Couns 2020 ; 29 : 518 – 529 . 32291871 8. Meghani SH , Byun E , Gallagher RM . Time to take stock: a meta-analysis and systematic review of analgesic treatment disparities for

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A Discrete Choice Experiment to Examine the Preferences of Patients With Cancer and Their Willingness to Pay for Different Types of Health Care Appointments

Shu Fen Wong, Richard Norman, Trisha Lynette Dunning, David Michael Ashley, Mustafa Khasraw, Theresa Margaret Hayes, Ian Collins, and Paula Kate Lorgelly

-stage breast cancer changed their preferences after a medical consultation. Choice-based techniques such as discrete choice experiments (DCE) 4 have been successfully used to evaluate genetic counseling for cancer, 5 screening programs, 6 and cancer

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NCCN News

example in a condition known as ‘mosaicism,’ in which the mutation is not present in all of the cells of the body). Because of this, the NCCN Guidelines continue to highlight the critical importance of genetic counseling for patients prior to undergoing

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NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2017

Mary B. Daly, Robert Pilarski, Michael Berry, Saundra S. Buys, Meagan Farmer, Susan Friedman, Judy E. Garber, Noah D. Kauff, Seema Khan, Catherine Klein, Wendy Kohlmann, Allison Kurian, Jennifer K. Litton, Lisa Madlensky, Sofia D. Merajver, Kenneth Offit, Tuya Pal, Gwen Reiser, Kristen Mahoney Shannon, Elizabeth Swisher, Shaveta Vinayak, Nicoleta C. Voian, Jeffrey N. Weitzel, Myra J. Wick, Georgia L. Wiesner, Mary Dwyer, and Susan Darlow

mother and/or father. 1 , 2 An individual suspected of being at risk for hereditary cancer should be offered genetic counseling. 3 , 4 The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Genetic/Familial High-Risk Assessment: Breast

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Cost-Effectiveness of Unselected Multigene Germline and Somatic Genetic Testing for Epithelial Ovarian Cancer

Ranjit Manchanda, Li Sun, Monika Sobocan, Isabel V. Rodriguez, Xia Wei, Ashwin Kalra, Samuel Oxley, Michail Sideris, Caitlin T. Fierheller, Robert D. Morgan, Dhivya Chandrasekaran, Kelly Rust, Pavlina Spiliopoulou, Rowan E. Miller, Shanthini M. Crusz, Michelle Lockley, Naveena Singh, Asma Faruqi, Laura Casey, Elly Brockbank, Saurabh Phadnis, Tina Mills-Baldock, Fatima El-Khouly, Lucy A. Jenkins, Andrew Wallace, Munaza Ahmed, Ajith Kumar, Elizabeth M. Swisher, Charlie Gourley, Barbara M. Norquist, D. Gareth Evans, and Rosa Legood

relatives that undergo genetic testing. Costs Costs are reported as 2019 prices. Both payer/societal-perspective analyses were undertaken. We included costs of germline testing, somatic testing, pretest and posttest genetic counseling, 51 , 52 BC and OC

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Chest Wall Leiomyosarcoma After Breast-Conservative Therapy for Early-Stage Breast Cancer in a Young Woman With Li-Fraumeni Syndrome

Eve Henry, Victor Villalobos, Lynn Million, Kristin C. Jensen, Robert West, Kristen Ganjoo, Alexandra Lebensohn, James M. Ford, and Melinda L. Telli

these NCCN Guidelines, visit NCCN.org ). 17 The NCCN Guidelines also recommend genetic counseling for patients who are considering p53 testing. 17 A multidisciplinary approach with professional geneticists, counselors, psychologists, and oncologists

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A Polycythemia Vera JAK2 Mutation Masquerading as a Duodenal Cancer Mutation

Justin Lee, Jennifer Axilbund, W. Brian Dalton, Daniel Laheru, Stanley Watkins, David Chu, Karen Cravero, Berry Button, Kelly Kyker-Snowman, Ian Waters, Christopher D. Gocke, Josh Lauring, and Ben Ho Park

definitively rule this out, because it would have implications for treatment and genetic counseling. Because blood could not be used in this instance as a source of germline DNA, we performed Sanger sequencing using DNA extracted from a buccal swab

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Meeting Patients Where They Are: Policy Platform for Telehealth and Cancer Care Delivery

Sheetal Kircher, Nicole Braccio, Kathleen Gallagher, Ruth Carlos, Lynne Wagner, Mary Lou Smith, Alan Balch, and Al B. Benson III

cancer care continuum, including navigation, chemotherapy toxicity management, genetic counseling, clinical trial enrollment, mental health services, survivorship care, and palliative care ( Figure 1 ). 6 – 8 Guidelines need to evolve to offer evidence