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NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2017

Mary B. Daly, Robert Pilarski, Michael Berry, Saundra S. Buys, Meagan Farmer, Susan Friedman, Judy E. Garber, Noah D. Kauff, Seema Khan, Catherine Klein, Wendy Kohlmann, Allison Kurian, Jennifer K. Litton, Lisa Madlensky, Sofia D. Merajver, Kenneth Offit, Tuya Pal, Gwen Reiser, Kristen Mahoney Shannon, Elizabeth Swisher, Shaveta Vinayak, Nicoleta C. Voian, Jeffrey N. Weitzel, Myra J. Wick, Georgia L. Wiesner, Mary Dwyer, and Susan Darlow

mother and/or father. 1 , 2 An individual suspected of being at risk for hereditary cancer should be offered genetic counseling. 3 , 4 The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Genetic/Familial High-Risk Assessment: Breast

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A Polycythemia Vera JAK2 Mutation Masquerading as a Duodenal Cancer Mutation

Justin Lee, Jennifer Axilbund, W. Brian Dalton, Daniel Laheru, Stanley Watkins, David Chu, Karen Cravero, Berry Button, Kelly Kyker-Snowman, Ian Waters, Christopher D. Gocke, Josh Lauring, and Ben Ho Park

definitively rule this out, because it would have implications for treatment and genetic counseling. Because blood could not be used in this instance as a source of germline DNA, we performed Sanger sequencing using DNA extracted from a buccal swab

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Barriers to Clinical Trial Participation as Perceived by Oncologists and Patients

Neal J. Meropol, Joanne S. Buzaglo, Jennifer Millard, Nevena Damjanov, Suzanne M. Miller, Caroline Ridgway, Eric A. Ross, John D. Sprandio, and Perry Watts

Fleisher L Roussi P . Facilitating informed decision making about breast cancer risk and genetic counseling among women calling the NCI's Cancer Information Service . J Health Commun 2005 ; 10 ( Suppl ): S119 – 136 . 21. Ellis PM . Attitudes

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New Therapies for Ovarian Cancer

David M. O’Malley

treatment should not be delayed for genetic counseling. For patients with recurrent or refractory disease, validated molecular testing should be performed in a CLIA-approved facility using the most recently obtained tissue. Testing for patients with

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Chest Wall Leiomyosarcoma After Breast-Conservative Therapy for Early-Stage Breast Cancer in a Young Woman With Li-Fraumeni Syndrome

Eve Henry, Victor Villalobos, Lynn Million, Kristin C. Jensen, Robert West, Kristen Ganjoo, Alexandra Lebensohn, James M. Ford, and Melinda L. Telli

these NCCN Guidelines, visit NCCN.org ). 17 The NCCN Guidelines also recommend genetic counseling for patients who are considering p53 testing. 17 A multidisciplinary approach with professional geneticists, counselors, psychologists, and oncologists

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Meeting Patients Where They Are: Policy Platform for Telehealth and Cancer Care Delivery

Sheetal Kircher, Nicole Braccio, Kathleen Gallagher, Ruth Carlos, Lynne Wagner, Mary Lou Smith, Alan Balch, and Al B. Benson III

cancer care continuum, including navigation, chemotherapy toxicity management, genetic counseling, clinical trial enrollment, mental health services, survivorship care, and palliative care ( Figure 1 ). 6 – 8 Guidelines need to evolve to offer evidence

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New Therapies for Ovarian Cancer

Deborah K. Armstrong

genetic counseling with “strong consideration” for genetic testing, she said. Due to their efficacy in ovarian cancer and some other malignancies, the use of PARP inhibitors has steadily grown since 2014, when olaparib was approved. At the time of Dr

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NCCN News

legislation that would remedy a longstanding Medicare gap, ensuring that beneficiaries at increased risk of cancer have access to standard-of-care genetic counseling, testing, screening, and risk-reducing interventions. This proposed law will enable coverage

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Abstracts From the NCCN 21st Annual Conference: Advancing the Standard of Cancer Care™

chemoprevention but opted out. Of the 306 patients, 48% (n=131) were eligible for genetic counseling, 27 genetic counseling appointments were scheduled but only 19 were kept, and genetic testing was conducted on 8% of patients (n=11), 7 of whom had negative

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When and How to Perform Genetic Testing for Inherited Colorectal Cancer Syndromes

Patrick M. Lynch

the Bayesian principles of Mendelian genetics involved in this process are straightforward, providing formal genetic counseling is nevertheless advisable in most instances, lest missteps in the testing process occur. 10 , 11 As suggested earlier, the