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Samuel L. Aitken, Jerod L. Nagel, Lilian Abbo, William Alegria, Jason N. Barreto, Sanjeet Dadwal, Alison G. Freifeld, Rupali Jain, Steven A. Pergam, Frank P. Tverdek, Susan K. Seo, and on behalf of the Antimicrobial Stewardship in Cancer Consortium ASCC

-specific, evidence-based guidelines and clinical pathways to standardize prescribing is not only feasible but necessary. Examples of highly used pathways in patients with cancer include the management of fever and neutropenia, antifungal prophylaxis and treatment

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Gary H. Lyman

R . Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer . N Engl J Med 1991 ; 325 : 164 – 170 . 18 Trillet-Lenoir V Green J Manegold C

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Derek Weycker, Xiaoyan Li, Rich Barron, Hongsheng Wu, P.K. Morrow, Hairong Xu, Maureen Reiner, Jacob Garcia, Shivani K. Mhatre, and Gary H. Lyman

Background Neutropenia is a common side effect of myelosuppressive chemotherapy that increases the risk of infection, which is typically signaled by fever. When neutropenic patients develop fever (ie, febrile neutropenia [FN]), the likelihood

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Gary H. Lyman and David C. Dale

( ELANE ). 21 , 22 Patients with cyclic neutropenia have oscillations in blood neutrophils usually at 3-week intervals, measured from nadir to nadir. During the period of most severe neutropenia, fever, severe mouth ulcers, pharyngitis, sinusitis, anal

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Jason D. Goldman, Amelia Gallaher, Rupali Jain, Zach Stednick, Manoj Menon, Michael J. Boeckh, Paul S. Pottinger, Stephen M. Schwartz, and Corey Casper

uncomplicated neutropenic fever, but differ regarding which antibiotics should be included in combination therapy for initial management of SS/SSh, reflecting sparse and conflicting data in patients with cancer and SS/SSh. We reasoned that intervening in the

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fevers, sweats, weight loss, and pneumonia. A surgical biopsy is often required to effectively diagnose a patient with mesothelioma according to Dr. Krug. PET scans can aid in staging as well, detecting unexpected metastases in 10 percent of cases

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M. Zach Koontz, Brendan M. Visser, and Pamela L. Kunz

emergency department with nausea, vomiting, fevers, tachycardia, and an elevated WBC count. CT showed new gas within the tumor, consistent with liquefaction necrosis. She was treated with antibiotics and discharged on continued imatinib. A contrast CT after

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Daniel G. Coit, John A. Thompson, Robert Andtbacka, Christopher J. Anker, Christopher K. Bichakjian, William E. Carson III, Gregory A. Daniels, Adil Daud, Dominick DiMaio, Martin D. Fleming, Rene Gonzalez, Valerie Guild, Allan C. Halpern, F. Stephen Hodi Jr, Mark C. Kelley, Nikhil I. Khushalani, Ragini R. Kudchadkar, Julie R. Lange, Mary C. Martini, Anthony J. Olszanski, Merrick I. Ross, April Salama, Susan M. Swetter, Kenneth K. Tanabe, Vijay Trisal, Marshall M. Urist, Nicole R. McMillian, and Maria Ho

or higher adverse events occurred in 53% of patients receiving dabrafenib, although grade 3 or 4 events were uncommon. The most frequent side effects were skin-related toxicity, fever, fatigue, arthralgia, and headache. Compared with vemurafenib

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Rebecca M. Shulman, David S. Weinberg, Eric A. Ross, Karen Ruth, Glenn F. Rall, Anthony J. Olszanski, James Helstrom, Michael J. Hall, Julia Judd, David Y.T. Chen, Robert G. Uzzo, Timothy P. Dougherty, Riley Williams, Daniel M. Geynisman, Carolyn Y. Fang, Richard I. Fisher, Marshall Strother, Erica Huelsmann, Sunil Adige, Peter D. Whooley, Kevin Zarrabi, Brinda Gupta, Pritish Iyer, Melissa McShane, Hilario Yankey, Charles T. Lee, Nina Burbure, Lauren E. Laderman, Julie Giurintano, Samuel Reiss, and Eric M. Horwitz

second vaccine dose. Vaccine recipients were asked to report whether they had experienced any of the following symptoms: tiredness, local pain or swelling at the injection site, joint pain, muscle pain, fever, chills, headache, nausea, or an allergic

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Pamala A. Pawloski, Cara L. McDermott, James H. Marshall, Vanita Pindolia, Catherine M. Lockhart, Catherine A. Panozzo, Jeffrey S. Brown, and Bernadette Eichelberger

identification of inpatient FN diagnoses during the first treatment cycle using ICD-9-CM codes in any position based on the following definitions: (1) narrow: a diagnosis of neutropenia (288.0x) and fever (780.6) on the same day; (2) intermediate: neutropenia