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Revisiting Minimally Invasive Surgery in the Management of Early-Stage Cervical Cancer

Kathryn P. Pennington, Renata R. Urban, and Heidi J. Gray

Use of minimally invasive surgery (MIS) in the management of early-stage cervical cancer (ESCC), previously considered an acceptable alternative to open surgery, 1 was recently challenged by results of the Laparoscopic Approach to Cervical

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Neoadjuvant Immunotherapy Leads to Major Response and Low Recurrence in Localized Mismatch Repair–Deficient Colorectal Cancer

Bin-Yi Xiao, Xuan Zhang, Tai-Yuan Cao, Dan-Dan Li, Wu Jiang, Ling-Heng Kong, Jing-Hua Tang, Kai Han, Chen-Zhi Zhang, Wei-Jian Mei, Jian Xiao, Zhi-Zhong Pan, Yun-Feng Li, Xiao-Shi Zhang, and Pei-Rong Ding

tissue, as per the clinical routine of the participating centers. Treatment and Follow-Up The decisions to treat patients with PD-1 inhibitors instead of surgery were made by the primary surgeons of the participating centers, with the most common

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Combined Modality Therapy of Localized Gastric and Esophageal Cancers

Prajnan Das, Norio Fukami, and Jaffer A. Ajani

comparison with previous meta-analyses . Tumori 2002 ; 88 : 21 – 27 . 35. Macdonald JS Smalley SR Benedetti J . Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction . N Engl

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Molecular Targeting of Dermatofibrosarcoma Protuberans: A New Approach to a Surgical Disease

Grant A. McArthur

. Fiore M Miceli R Mussi C . Dermatofibrosarcoma protuberans treated at a single institution: a surgical disease with a high cure rate . J Clin Oncol 2005 ; 23 : 7669 – 7675 . 4. Chang CK Jacobs IA Salti GI . Outcomes of surgery for

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Minimally Invasive Surgery for Esophageal Cancer

Alfredo A. Santillan, Jeffrey M. Farma, Kenneth L. Meredith, Nilay R. Shah, and Scott T. Kelley

, 2007 . CA Cancer J Clin 2007 ; 57 : 43 – 66 . 3. Kelsen DP Ginsberg R Pajak TF . Chemotherapy followed by surgery compared with surgery alone for localized esophageal cancer . N Engl J Med 1998 ; 339 : 1979 – 1984 . 4

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Advances in Breast Surgery, 2002-2012

Stephen B. Edge

clinical trials. Early trials showed that extended surgery (“local therapy”) does not improve mortality over less aggressive surgery. Trials conducted in the 1970s and 1980s clearly showed that radical surgery involving removal of the breast provides no

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Subdivision of M1 Stage for De Novo Metastatic Breast Cancer to Better Predict Prognosis and Response to Primary Tumor Surgery

Caijin Lin, Jiayi Wu, Shuning Ding, Chihwan Goh, Lisa Andriani, Shuangshuang Lu, Kunwei Shen, and Li Zhu

– 11 De novo MBC is considered incurable but treatable. Generally, systemic therapy is viewed as the mainstay of treatment. 12 Primary tumor surgery is considered in selected patients, mostly in the palliative setting for those with impending

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Optimal Surveillance Strategies After Surgery for Renal Cell Carcinoma

Mark D. Tyson and Sam S. Chang

salvage therapies. 7 Although most recurrences present within the first couple of years after surgery and approximately half of all distant recurrences occur in the lung, late recurrences and nonpulmonary sites of metastatic disease are not uncommon. 5

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The Role of Cytoreductive/Debulking Surgery in Ovarian Cancer

Mark T. Wakabayashi, Paul S. Lin, and Amy A. Hakim

Edited by Kerrin G. Robinson

debulking surgery . J Surg Oncol 1991 ; 48 : 39 – 44 . 4. McGuire WP Hoskins WJ Brady MF . Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer . N Engl J Med 1996

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The Integration of Chemotherapy and Surgery for Bladder Cancer

Matthew D. Galsky, Harry W. Herr, and Dean F. Bajorin

: 3020 – 3028 . 4 Herr HW : Surgical factors in bladder cancer: more (nodes) + more (pathology) = less (mortality) . BJU Int 2003 ; 92 : 187 – 188 . 5 Herr HW : Extent of surgery and pathology evaluation has an impact on bladder