/TPI (35 mg/m 2 twice daily) and oxaliplatin (85 mg/m 2 ) before undergoing concurrent chemoradiation (standard-of-care radiation dose of 5,040 cGy will be used at all participating study sites) with carboplatin (area under the curve, 2) and paclitaxel (50
Search Results
Highlights of the NCCN Oncology Research Program
Updates to Treatment of Recurrent Metastatic Head and Neck Cancers
Presented by: Cristina P. Rodriguez
10 found that pembrolizumab + BCA 101 (bifunctional EGFR monoclonal antibody with TGFβ modulator; N=20) resulted in a 44% ORR. Non–5-FU combinations with pembrolizumab are also emerging. The KEYNOTE-B10 trial combined carboplatin, paclitaxel, and
Highlights of the NCCN Oncology Research Program
,040 cGy will be used at all participating study sites) with carboplatin (area under the curve, 2) and paclitaxel (50 mg/m 2 ) for 6 weeks, followed by surgery. FTD/TPI will be self-administered (in tablet form) twice daily by study participants and
Highlights of the NCCN Oncology Research Program
will be used at all participating study sites) with carboplatin (area under the curve, 2) and paclitaxel (50 mg/m2) for 6 weeks, followed by surgery. FTD/TPI will be self-administered (in tablet form) twice daily by study participants and documented in
Use of PARP Inhibitors for Ovarian Cancer
Presented by: Deborah K. Armstrong
The study’s first arm was placebo + carboplatin/paclitaxel followed by placebo as maintenance. Arm 2 was veliparib + carboplatin/paclitaxel followed by placebo. Arm 3 was veliparib + carboplatin/paclitaxel followed by veliparib maintenance. An
Highlights of the NCCN Oncology Research Program
dose of 5,040 cGy will be used at all participating study sites) with carboplatin (area under the curve, 2) and paclitaxel (50 mg/m2) for 6 weeks, followed by surgery. FTD/TPI will be self-administered (in tablet form) twice daily by study participants
Highlights of the NCCN Oncology Research Program
/TPI (35 mg/m 2 twice daily) and oxaliplatin (85 mg/m 2 ) before undergoing concurrent chemoradiation (standard-of-care radiation dose of 5,040 cGy will be used at all participating study sites) with carboplatin (area under the curve 2) and paclitaxel (50
Metastatic Spiradenocarcinoma Managed With PD-1 Inhibition
Jeffrey J. Wargo, David R. Carr, Jose A. Plaza, and Claire F. Verschraegen
of PD-L1. The combination of carboplatin and paclitaxel was administered every 3 weeks for 4 cycles, but the disease progressed in the right lung. She was then referred to Ohio State University, and 200 mg of pembrolizumab was administered
Adjuvant Chemotherapy for Lung Cancer: Cisplatin Doublets Only?
Daniel Morgensztern and Ramaswamy Govindan
randomised controlled trial . Lancet Oncol 2006 ; 7 : 719 – 727 . 13. Strauss GM Herndon J Maddaus MA . Randomized clinical trial of adjuvant chemotherapy with paclitaxel and carboplatin following resection in stage IB non-small cell lung
Impact of Pain on Symptom Burden in Chemotherapy-Induced Peripheral Neurotoxicity
Fawaz Mayez Mahfouz, Tiffany Li, Hannah C. Timmins, Lisa G. Horvath, Michelle Harrison, Peter Grimison, Gavin Marx, David Goldstein, and Susanna B. Park
CIPN (NCI-CTCAE ≥2) and No Pain Versus With Pain Comparison of CIPN Subgroups Among Different Chemotherapy Types The 2 largest chemotherapy-type cohorts (paclitaxel and oxaliplatin) were selected for group comparisons. There were significant